Cerebral cavernous malformations arise from endothelial gain of MEKK3–KLF2/4 signalling von Zhou, Zinan, Tang, Alan T., Wong, Weng-Yew, Bamezai, Sharika, Goddard, Lauren M., Shenkar, Robert, Zhou, Su, Yang, Jisheng, Wright, Alexander C., Foley, Matthew, Arthur, J. Simon C., Whitehead, Kevin J., Awad, Issam A., Li, Dean Y., Zheng, Xiangjian, Kahn, Mark L.

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Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains von Emmerich, Christoph H., Ordureau, Alban, Strickson, Sam, Arthur, J. Simon C., Pedrioli, Patrick G. A., Komander, David, Cohen, Philip

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The selectivity of protein kinase inhibitors: a further update von Bain, Jenny, Plater, Lorna, Elliott, Matt, Shpiro, Natalia, Hastie, C James, McLauchlan, Hilary, Klevernic, Iva, Arthur, J Simon C, Alessi, Dario R, Cohen, Philip

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Mitogen-activated protein kinases in innate immunity von Arthur, J. Simon C., Ley, Steven C.

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STAT3 activation by E6 is essential for the differentiation-dependent HPV18 life cycle von Morgan, Ethan L, Wasson, Christopher W, Hanson, Lucy, Kealy, David, Pentland, Ieisha, McGuire, Victoria, Scarpini, Cinzia, Coleman, Nicholas, Arthur, J Simon C, Parish, Joanna L, Roberts, Sally, Macdonald, Andrew

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The Cerebral Cavernous Malformation Pathway Controls Cardiac Development via Regulation of Endocardial MEKK3 Signaling and KLF Expression von Zhou, Zinan, Rawnsley, David R., Goddard, Lauren M., Pan, Wei, Cao, Xing-Jun, Jakus, Zoltan, Zheng, Hui, Yang, Jisheng, Arthur, J. Simon C., Whitehead, Kevin J., Li, Dean, Zhou, Bin, Garcia, Benjamin A., Zheng, Xiangjian, Kahn, Mark L.

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RAS–MAPK–MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1 von Park, Jeehye, Al-Ramahi, Ismael, Tan, Qiumin, Mollema, Nissa, Diaz-Garcia, Javier R., Gallego-Flores, Tatiana, Lu, Hsiang-Chih, Lagalwar, Sarita, Duvick, Lisa, Kang, Hyojin, Lee, Yoontae, Jafar-Nejad, Paymaan, Sayegh, Layal S., Richman, Ronald, Liu, Xiuyun, Gao, Yan, Shaw, Chad A., Arthur, J. Simon C., Orr, Harry T., Westbrook, Thomas F., Botas, Juan, Zoghbi, Huda Y.

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Quantitative proteomics reveals tissue-specific, infection-induced and species-specific neutrophil protein signatures von Sollberger, Gabriel, Brenes, Alejandro J., Warner, Jordan, Arthur, J. Simon C., Howden, Andrew J. M.

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Experience recruits MSK1 to expand the dynamic range of synapses and enhance cognition von Privitera, Lucia, Morè, Lorenzo, Cooper, Daniel D, Richardson, Philippa, Tsogka, Marianthi, Hebenstreit, Daniel, Arthur, J Simon C, Frenguelli, Bruno G

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Regulation of miRNA transcription in macrophages in response to Candida albicans von Monk, Claire E, Hutvagner, György, Arthur, J Simon C

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Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages von Clark, Kristopher, MacKenzie, Kirsty F, Petkevicius, Kasparas, Kristariyanto, Yosua, Zhang, Jiazhen, Choi, Hwan Geun, Peggie, Mark, Plater, Lorna, Pedrioli, Patrick G. A, McIver, Ed, Gray, Nathanael S, Arthur, J. Simon C, Cohen, Philip

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Polyubiquitin binding to ABIN1 is required to prevent autoimmunity von Nanda, Sambit K, Venigalla, Ram K C, Ordureau, Alban, Patterson-Kane, Janet C, Powell, David W, Toth, Rachel, Arthur, J Simon C, Cohen, Philip

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Regulation of the miR-212/132 locus by MSK1 and CREB in response to neurotrophins von Remenyi, Judit, Hunter, Christopher J, Cole, Christian, Ando, Hideaki, Impey, Soren, Monk, Claire E, Martin, Kirsty J, Barton, Geoffrey J, Hutvagner, Gyorgy, Arthur, J Simon C

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Dectin-1 regulates IL-10 production via a MSK1/2 and CREB dependent pathway and promotes the induction of regulatory macrophage markers von Elcombe, Suzanne E, Naqvi, Shaista, Van Den Bosch, Mirjam W M, MacKenzie, Kirsty F, Cianfanelli, Francesca, Brown, Gordon D, Arthur, J Simon C

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The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling von Ananieva, Olga, Iversen, Lars, Santos, Susana G, Johansen, Claus, Carr, Julia M, Darragh, Joanne, Park, Jin Mo, McIlrath, Joanne, Monk, Claire E, Arthur, J Simon C, Toth, Rachel, Wingate, Andrew

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The catalytic subunit of the system L1 amino acid transporter (slc7a5) facilitates nutrient signalling in mouse skeletal muscle von Poncet, Nadège, Mitchell, Fiona E, Ibrahim, Adel F M, McGuire, Victoria A, English, Grant, Arthur, J Simon C, Shi, Yun-Bo, Taylor, Peter M

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p38γ and p38δ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation von Risco, Ana, del Fresno, Carlos, Mambol, Agnes, Alsina-Beauchamp, Dayanira, MacKenzie, Kirsty F, Yang, Huei-Ting, Barber, Domingo F, Morcelle, Carmen, Arthur, J. Simon C, Ley, Steven C, Ardavin, Carlos, Cuenda, Ana

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Generation of a chemical genetic model for JAK3 von Remenyi, Judit, Naik, Rangeetha Jayaprakash, Wang, Jinhua, Razsolkov, Momchil, Verano, Alyssa, Cai, Quan, Tan, Li, Toth, Rachel, Raggett, Samantha, Baillie, Carla, Traynor, Ryan, Hastie, C. James, Gray, Nathanael S., Arthur, J. Simon C.

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The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways von Watts, Colin, Zaru, Rossana, Ronkina, Natalia, Gaestel, Matthias, Arthur, J Simon C

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Micro-CT Imaging Reveals Mekk3 Heterozygosity Prevents Cerebral Cavernous Malformations in Ccm2-Deficient Mice von Choi, Jaesung P, Foley, Matthew, Zhou, Zinan, Wong, Weng-Yew, Gokoolparsadh, Naveena, Arthur, J Simon C, Li, Dean Y, Zheng, Xiangjian

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