Disease candidate gene identification and prioritization using protein interaction networks von Chen, Jing, Aronow, Bruce J, Jegga, Anil G

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Single-cell analysis of mixed-lineage states leading to a binary cell fate choice von Olsson, Andre, Venkatasubramanian, Meenakshi, Chaudhri, Viren K., Aronow, Bruce J., Salomonis, Nathan, Singh, Harinder, Grimes, H. Leighton

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The Pan-ErbB Negative Regulator Lrig1 Is an Intestinal Stem Cell Marker that Functions as a Tumor Suppressor von Powell, Anne E., Wang, Yang, Li, Yina, Poulin, Emily J., Means, Anna L., Washington, Mary K., Higginbotham, James N., Juchheim, Alwin, Prasad, Nripesh, Levy, Shawn E., Guo, Yan, Shyr, Yu, Aronow, Bruce J., Haigis, Kevin M., Franklin, Jeffrey L., Coffey, Robert J.

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A Shh-Foxf-Fgf18-Shh Molecular Circuit Regulating Palate Development von Xu, Jingyue, Liu, Han, Lan, Yu, Aronow, Bruce J, Kalinichenko, Vladimir V, Jiang, Rulang

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Genetic lineage tracing defines myofibroblast origin and function in the injured heart von Kanisicak, Onur, Khalil, Hadi, Ivey, Malina J., Karch, Jason, Maliken, Bryan D., Correll, Robert N., Brody, Matthew J., J. Lin, Suh-Chin, Aronow, Bruce J., Tallquist, Michelle D., Molkentin, Jeffery D.

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Improved human disease candidate gene prioritization using mouse phenotype von Chen, Jing, Xu, Huan, Aronow, Bruce J, Jegga, Anil G

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Blockade of Chronic Type I Interferon Signaling to Control Persistent LCMV Infection von Wilson, Elizabeth B., Yamada, Douglas H., Elsaesser, Heidi, Herskovitz, Jonathan, Deng, Jane, Cheng, Genhong, Aronow, Bruce J., Karp, Christopher L., Brooks, David G.

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A roadmap for the Human Developmental Cell Atlas von Haniffa, Muzlifah, Taylor, Deanne, Linnarsson, Sten, Aronow, Bruce J., Bader, Gary D., Barker, Roger A., Camara, Pablo G., Camp, J. Gray, Chédotal, Alain, Copp, Andrew, Etchevers, Heather C., Giacobini, Paolo, Göttgens, Berthold, Guo, Guoji, Hupalowska, Ania, James, Kylie R., Kirby, Emily, Kriegstein, Arnold, Lundeberg, Joakim, Marioni, John C., Meyer, Kerstin B., Niakan, Kathy K., Nilsson, Mats, Olabi, Bayanne, Pe’er, Dana, Regev, Aviv, Rood, Jennifer, Rozenblatt-Rosen, Orit, Satija, Rahul, Teichmann, Sarah A., Treutlein, Barbara, Vento-Tormo, Roser, Webb, Simone

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Computational drug repositioning through heterogeneous network clustering von Wu, Chao, Gudivada, Ranga C, Aronow, Bruce J, Jegga, Anil G

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A Thrombospondin-Dependent Pathway for a Protective ER Stress Response von Lynch, Jeffrey M., Maillet, Marjorie, Vanhoutte, Davy, Schloemer, Aryn, Sargent, Michelle A., Blair, N. Scott, Lynch, Kaari A., Okada, Tetsuya, Aronow, Bruce J., Osinska, Hanna, Prywes, Ron, Lorenz, John N., Mori, Kazutoshi, Lawler, Jack, Robbins, Jeffrey, Molkentin, Jeffery D.

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Expression Profiling of Fibroblasts in Chronic and Acute Disease Models Reveals Novel Pathways in Kidney Fibrosis von Higashi, Atsuko Y, Aronow, Bruce J, Dressler, Gregory R

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Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response von Haberman, Yael, Karns, Rebekah, Dexheimer, Phillip J., Schirmer, Melanie, Somekh, Judith, Jurickova, Ingrid, Braun, Tzipi, Novak, Elizabeth, Bauman, Laura, Collins, Margaret H., Mo, Angela, Rosen, Michael J., Bonkowski, Erin, Gotman, Nathan, Marquis, Alison, Nistel, Mason, Rufo, Paul A., Baker, Susan S., Sauer, Cary G., Markowitz, James, Pfefferkorn, Marian D., Rosh, Joel R., Boyle, Brendan M., Mack, David R., Baldassano, Robert N., Shah, Sapana, Leleiko, Neal S., Heyman, Melvin B., Grifiths, Anne M., Patel, Ashish S., Noe, Joshua D., Aronow, Bruce J., Kugathasan, Subra, Walters, Thomas D., Gibson, Greg, Thomas, Sonia Davis, Mollen, Kevin, Shen-Orr, Shai, Huttenhower, Curtis, Xavier, Ramnik J., Hyams, Jeffrey S., Denson, Lee A.

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Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling von Giles, Daniel A, Moreno-Fernandez, Maria E, Stankiewicz, Traci E, Graspeuntner, Simon, Cappelletti, Monica, Wu, David, Mukherjee, Rajib, Chan, Calvin C, Lawson, Matthew J, Klarquist, Jared, Sünderhauf, Annika, Softic, Samir, Kahn, C Ronald, Stemmer, Kerstin, Iwakura, Yoichiro, Aronow, Bruce J, Karns, Rebekah, Steinbrecher, Kris A, Karp, Christopher L, Sheridan, Rachel, Shanmukhappa, Shiva K, Reynaud, Damien, Haslam, David B, Sina, Christian, Rupp, Jan, Hogan, Simon P, Divanovic, Senad

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A mechanistic model and therapeutic interventions for COVID-19 involving a RAS-mediated bradykinin storm von Garvin, Michael R., Alvarez, Christiane, Miller, J. Izaak, Prates, Erica T., Walker, Angelica M., Amos, B. Kirtley, Mast, Alan E., Justice, Amy, Aronow, Bruce, Jacobson, Daniel

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Transdifferentiation of human fibroblasts to endothelial cells: role of innate immunity von Sayed, Nazish, Wong, Wing Tak, Ospino, Frank, Meng, Shu, Lee, Jieun, Jha, Arshi, Dexheimer, Phillip, Aronow, Bruce J, Cooke, John P

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Single-cell RNA sequencing identifies inflammatory tissue T cells in eosinophilic esophagitis von Wen, Ting, Aronow, Bruce J, Rochman, Yrina, Rochman, Mark, Kc, Kiran, Dexheimer, Phil J, Putnam, Philip, Mukkada, Vincent, Foote, Heather, Rehn, Kira, Darko, Sam, Douek, Daniel, Rothenberg, Marc E

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MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors von Jessen, Walter J, Miller, Shyra J, Jousma, Edwin, Wu, Jianqiang, Rizvi, Tilat A, Brundage, Meghan E, Eaves, David, Widemann, Brigitte, Kim, Mi-Ok, Dombi, Eva, Sabo, Jessica, Hardiman Dudley, Atira, Niwa-Kawakita, Michiko, Page, Grier P, Giovannini, Marco, Aronow, Bruce J, Cripe, Timothy P, Ratner, Nancy

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Intrinsic Age-Dependent Changes and Cell-Cell Contacts Regulate Nephron Progenitor Lifespan von Chen, Shuang, Brunskill, Eric W., Potter, S. Steven, Dexheimer, Phillip J., Salomonis, Nathan, Aronow, Bruce J., Hong, Christian I., Zhang, Tongli, Kopan, Raphael

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Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis von Weng, Qinjie, Wang, Jincheng, Wang, Jiajia, He, Danyang, Cheng, Zuolin, Zhang, Feng, Verma, Ravinder, Xu, Lingli, Dong, Xinran, Liao, Yunfei, He, Xuelian, Potter, Andrew, Zhang, Liguo, Zhao, Chuntao, Xin, Mei, Zhou, Qian, Aronow, Bruce J., Blackshear, Perry J., Rich, Jeremy N., He, Qiaojun, Zhou, Wenhao, Suvà, Mario L., Waclaw, Ronald R., Potter, S. Steven, Yu, Guoqiang, Lu, Q. Richard

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ToppCluster: a multiple gene list feature analyzer for comparative enrichment clustering and network-based dissection of biological systems von Kaimal, Vivek, Bardes, Eric E, Tabar, Scott C, Jegga, Anil G, Aronow, Bruce J

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