Acute Myelogenous Leukemia-Induced Sympathetic Neuropathy Promotes Malignancy in an Altered Hematopoietic Stem Cell Niche von Hanoun, Maher, Zhang, Dachuan, Mizoguchi, Toshihide, Pinho, Sandra, Pierce, Halley, Kunisaki, Yuya, Lacombe, Julie, Armstrong, Scott A., Dührsen, Ulrich, Frenette, Paul S.

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Exploiting the Epigenome to Control Cancer-Promoting Gene-Expression Programs von Brien, Gerard L., Valerio, Daria G., Armstrong, Scott A.

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The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia von Stein, Eytan M., Garcia-Manero, Guillermo, Rizzieri, David A., Tibes, Raoul, Berdeja, Jesus G., Savona, Michael R., Jongen-Lavrenic, Mojca, Altman, Jessica K., Thomson, Blythe, Blakemore, Stephen J., Daigle, Scott R., Waters, Nigel J., Suttle, A. Benjamin, Clawson, Alicia, Pollock, Roy, Krivtsov, Andrei, Armstrong, Scott A., DiMartino, Jorge, Hedrick, Eric, Löwenberg, Bob, Tallman, Martin S.

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Targeting chromatin complexes in fusion protein-driven malignancies von Brien, Gerard L., Stegmaier, Kimberly, Armstrong, Scott A.

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Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands von Remillard, David, Buckley, Dennis L., Paulk, Joshiawa, Brien, Gerard L., Sonnett, Matthew, Seo, Hyuk‐Soo, Dastjerdi, Shiva, Wühr, Martin, Dhe‐Paganon, Sirano, Armstrong, Scott A., Bradner, James E.

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PI3K pathway regulates ER-dependent transcription in breast cancer through the epigenetic regulator KMT2D von Toska, Eneda, Osmanbeyoglu, Hatice U., Castel, Pau, Chan, Carmen, Hendrickson, Ronald C., Elkabets, Moshe, Dickler, Maura N., Scaltriti, Maurizio, Leslie, Christina S., Armstrong, Scott A., Baselga, José

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A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia von Krivtsov, Andrei V., Evans, Kathryn, Gadrey, Jayant Y., Eschle, Benjamin K., Hatton, Charlie, Uckelmann, Hannah J., Ross, Kenneth N., Perner, Florian, Olsen, Sarah N., Pritchard, Tara, McDermott, Lisa, Jones, Connor D., Jing, Duohui, Braytee, Ali, Chacon, Diego, Earley, Eric, McKeever, Brian M., Claremon, David, Gifford, Andrew J., Lee, Heather J., Teicher, Beverly A., Pimanda, John E., Beck, Dominik, Perry, Jennifer A., Smith, Malcolm A., McGeehan, Gerard M., Lock, Richard B., Armstrong, Scott A.

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A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription von Wang, Shu-Ping, Tang, Zhanyun, Chen, Chun-Wei, Shimada, Miho, Koche, Richard P., Wang, Lan-Hsin, Nakadai, Tomoyoshi, Chramiec, Alan, Krivtsov, Andrei V., Armstrong, Scott A., Roeder, Robert G.

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A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response von Hoshii, Takayuki, Cifani, Paolo, Feng, Zhaohui, Huang, Chun-Hao, Koche, Richard, Chen, Chun-Wei, Delaney, Christopher D., Lowe, Scott W., Kentsis, Alex, Armstrong, Scott A.

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The menin-MLL1 interaction is a molecular dependency in NUP98-rearranged AML von Heikamp, Emily B., Henrich, Jill A., Perner, Florian, Wong, Eric M., Hatton, Charles, Wen, Yanhe, Barwe, Sonali P., Gopalakrishnapillai, Anilkumar, Xu, Haiming, Uckelmann, Hannah J., Takao, Sumiko, Kazansky, Yaniv, Pikman, Yana, McGeehan, Gerard M., Kolb, Edward A., Kentsis, Alex, Armstrong, Scott A.

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Recent progress toward epigenetic therapies: the example of mixed lineage leukemia von Neff, Tobias, Armstrong, Scott A.

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Chromatin-modifying enzymes as modulators of reprogramming von Onder, Tamer T., Kara, Nergis, Cherry, Anne, Sinha, Amit U., Zhu, Nan, Bernt, Kathrin M., Cahan, Patrick, Mancarci, B. Ogan, Unternaehrer, Juli, Gupta, Piyush B., Lander, Eric S., Armstrong, Scott A., Daley, George Q.

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Hematopoietic Differentiation Is Required for Initiation of Acute Myeloid Leukemia von Ye, Min, Zhang, Hong, Yang, Henry, Koche, Richard, Staber, Philipp B., Cusan, Monica, Levantini, Elena, Welner, Robert S., Bach, Christian S., Zhang, Junyan, Krivtsov, Andrei V., Armstrong, Scott A., Tenen, Daniel G.

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Selective Killing of Mixed Lineage Leukemia Cells by a Potent Small-Molecule DOT1L Inhibitor von Daigle, Scott R., Olhava, Edward J., Therkelsen, Carly A., Majer, Christina R., Sneeringer, Christopher J., Song, Jeffrey, Johnston, L. Danielle, Scott, Margaret Porter, Smith, Jesse J., Xiao, Yonghong, Jin, Lei, Kuntz, Kevin W., Chesworth, Richard, Moyer, Mikel P., Bernt, Kathrin M., Tseng, Jen-Chieh, Kung, Andrew L., Armstrong, Scott A., Copeland, Robert A., Richon, Victoria M., Pollock, Roy M.

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Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members von Certo, Michael, Moore, Victoria Del Gaizo, Nishino, Mari, Wei, Guo, Korsmeyer, Stanley, Armstrong, Scott A., Letai, Anthony

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MEN1 mutations mediate clinical resistance to menin inhibition von Perner, Florian, Stein, Eytan M., Wenge, Daniela V., Singh, Sukrit, Kim, Jeonghyeon, Apazidis, Athina, Rahnamoun, Homa, Anand, Disha, Marinaccio, Christian, Hatton, Charlie, Wen, Yanhe, Stone, Richard M., Schaller, David, Mowla, Shoron, Xiao, Wenbin, Gamlen, Holly A., Stonestrom, Aaron J., Persaud, Sonali, Ener, Elizabeth, Cutler, Jevon A., Doench, John G., McGeehan, Gerard M., Volkamer, Andrea, Chodera, John D., Nowak, Radosław P., Fischer, Eric S., Levine, Ross L., Armstrong, Scott A., Cai, Sheng F.

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Drugging Chromatin in Cancer: Recent Advances and Novel Approaches von Cai, Sheng F., Chen, Chun-Wei, Armstrong, Scott A.

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HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis von Sun, Yuqing, Zhou, Bo, Mao, Fengbiao, Xu, Jing, Miao, Hongzhi, Zou, Zhenhua, Phuc Khoa, Le Tran, Jang, Younghoon, Cai, Sheng, Witkin, Matthew, Koche, Richard, Ge, Kai, Dressler, Gregory R., Levine, Ross L., Armstrong, Scott A., Dou, Yali, Hess, Jay L.

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AKT/FOXO Signaling Enforces Reversible Differentiation Blockade in Myeloid Leukemias von Sykes, Stephen M., Lane, Steven W., Bullinger, Lars, Kalaitzidis, Demetrios, Yusuf, Rushdia, Saez, Borja, Ferraro, Francesca, Mercier, Francois, Singh, Harshabad, Brumme, Kristina M., Acharya, Sanket S., Schöll, Claudia, Tothova, Zuzana, Attar, Eyal C., Fröhling, Stefan, DePinho, Ronald A., Armstrong, Scott A., Gilliland, D. Gary, Scadden, David T.

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CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma von Huang, Chun-Hao, Lujambio, Amaia, Zuber, Johannes, Tschaharganeh, Darjus F, Doran, Michael G, Evans, Michael J, Kitzing, Thomas, Zhu, Nan, de Stanchina, Elisa, Sawyers, Charles L, Armstrong, Scott A, Lewis, Jason S, Sherr, Charles J, Lowe, Scott W

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