Generation of a novel CD30+ B cell subset producing GM‐CSF and its possible link to the pathogenesis of systemic sclerosis von Higashioka, K., Kikushige, Y., Ayano, M., Kimoto, Y., Mitoma, H., Kikukawa, M., Akahoshi, M., Arinobu, Y., Horiuchi, T., Akashi, K., Niiro, H.

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Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation von Iwasaki, Hiromi, Somoza, Chamorro, Shigematsu, Hirokazu, Duprez, Estelle A., Iwasaki-Arai, Junko, Mizuno, Shin-ichi, Arinobu, Yojiro, Geary, Kristin, Zhang, Pu, Dayaram, Tajhal, Fenyus, Maris L., Elf, Shannon, Chan, Susan, Kastner, Philippe, Huettner, Claudia S., Murray, Richard, Tenen, Daniel G., Akashi, Koichi

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Single pancreatic beta cells co-express multiple islet hormone genes in mice von Katsuta, H, Akashi, T, Katsuta, R, Nagaya, M, Kim, D, Arinobu, Y, Hara, M, Bonner-Weir, S, Sharma, A. J, Akashi, K, Weir, G. C

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OP0093 Comparison of CD34-Selected and Unmanipulated Autologous Hematopoietic Stem Cell Transplantation for Systemic Sclerosis: Four-Year Follow-Up Results von Tsukamoto, H., Ayano, M., Miyamoto, T., Niiro, H., Arinobu, Y., Akahoshi, M., Akashi, K.

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Ile50Val variant of IL4Rα upregulates IgE synthesis and associates with atopic asthma von Shirakawa, Taro, Mitsuyasu, Hiromichi, Izuhara, Kenji, Mao, Xiao-Quan, Gao, Pei-Song, Arinobu, Yojiro, Enomoto, Tadao, Kawai, Mitsuru, Sasaki, Sei, Dake, Yasuhiro, Hamasaki, Naotaka, Hopkin, Julian M

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Genetic variants of IL-13 signalling and human asthma and atopy von HEINZMANN, A, MAO, X.-Q, ROBERTS, M. H, SUGIMOTO, R, ARIMA, K, ARINOBU, Y, YU, B, KRUSE, S, ENOMOTO, T, DAKE, Y, KAWAI, M, SHIMAZU, S, AKAIWA, M, SASAKI, S, ADRA, C. N, KITAICHI, M, INOUE, H, YAMAUCHI, K, TOMICHI, N, KURIMOTO, F, HAMASAKI, N, HOPKIN, J. M, IZUHARA, K, KREOMER, R. T, SHIRAKAWA, T, DEICHMANN, K. A, GAO, P.-S, OHSHIMA, K, UMESHITA, R, ABE, Y, BRAUN, S, YAMASHITA, T

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FRI0406 Seven-year follow-up of autologous hematopoietic stem cell transplantation for severe systemic sclerosis von Tsukamoto, H., Horiuchi, T., Miyamoto, T., Niiro, H., Arinobu, Y., Akahoshi, M., Ayano, M., Tanaka, A., Ueda, N., Akashi, K.

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AB0201 Cell Surface Expression of DNAM-1 (CD226) on CD8+ T Cells is Increased in Patients with Systemic Sclerosis von Ayano, M., Tsukamoto, H., Tanaka, A., Nakano, S., Ueki, N., Ueda, S., Hisamoto, S., Ota, S.-I., Akahoshi, M., Arinobu, Y., Niiro, H., Horiuchi, T., Akashi, K.

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THU0063 Serum Progranulin Levels are Elevated in Dermatomyositis Patients with Acute Interstitial Lung Disease, Reflecting Severity and Prognosis von Tanaka, A., Tsukamoto, H., Ueda, N., Ayano, M., Ohta, S.-I., Ueki, N., Ueda, S., Hisamoto, S., Oryoji, D., Hirosaki, Y., Akahoshi, M., Arinobu, Y., Niiro, H., Horiuchi, T., Tada, Y., Akashi, K.

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THU0168 Serum progranulin levels are elevated in patients with systemic lupus erythematosus, reflecting disease activity von Tanaka, A., Tsukamoto, H., Mitoma, H., Ueda, N., Ayano, M., Ohta, S.-I., Inoue, Y., Arinobu, Y., Niiro, H., Horiuchi, T., Akashi, K.

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THU0238 Long-term follow-up of autologous hematopoietic stem cell transplantation for severe systemic sclerosis von Tsukamoto, H., Horiuchi, T., Miyamoto, T., Niiro, H., Arinobu, Y., Inoue, Y., Ayano, M., Tanaka, A., Ueda, N., Harada, M., Akashi, K.

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Activation of caspase-1 is mediated by stimulation of interferon genes and NLR family pyrin domain containing 3 in monocytes of active systemic lupus erythematosus von Inokuchi, Shoichiro, Mitoma, Hiroki, Kawano, Shotaro, Ayano, Masahiro, Kimoto, Yasutaka, Akahoshi, Mitsuteru, Arinobu, Yojiro, Akashi, Koichi, Horiuchi, Takahiko, Niiro, Hiroaki

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Developmental Checkpoints of the Basophil/Mast Cell Lineages in Adult Murine Hematopoiesis von Yojiro Arinobu, Iwasaki, Hiromi, Gurish, Michael F., Mizuno, Shin-ichi, Hirokazu Shigematsu, Hidetoshi Ozawa, Tenen, Daniel G., Austen, K. Frank, Akashi, Koichi

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Identification of eosinophil lineage-committed progenitors in the murine bone marrow von Iwasaki, Hiromi, Mizuno, Shin-ichi, Mayfield, Robin, Shigematsu, Hirokazu, Arinobu, Yojiro, Seed, Brian, Gurish, Michael F, Takatsu, Kiyoshi, Akashi, Koichi

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Variants of STAT6 (signal transducer and activator of transcription 6) in atopic asthma von GAO, P-S, MAO, X-Q, ROBERTS, M H, ARINOBU, Y, AKAIWA, M, ENOMOTO, T, DAKE, Y, KAWAI, M, SASAKI, S, HAMASAKI, N, IZUHARA, K, SHIRAKAWA, T, HOPKIN, J M

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Analysis of immune reconstitution after autologous CD34+ stem/progenitor cell transplantation for systemic sclerosis: predominant reconstitution of Th1 CD4+ T cells von TSUKAMOTO, Hiroshi, NAGAFUJI, Koji, TESHIMA, Takanori, HARADA, Mine, AKASHI, Koichi, HORIUCHI, Takahiko, MITOMA, Hiroki, NIIRO, Hiroaki, ARINOBU, Yojiro, INOUE, Yasushi, TO, Kentaro, MIYAMOTO, Toshihiro, IWASAKI, Hiromi

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CD4 T-cell autoreactivity to the mitochondrial autoantigen PDC-E2 in AMA-negative primary biliary cirrhosis von Shimoda, Shinji, Miyakawa, Hiroshi, Nakamura, Minoru, Ishibashi, Hiromi, Kikuchi, Kentaro, Kita, Hiroto, Niiro, Hiroaki, Arinobu, Youjirou, Ono, Nobuyuki, Mackay, Ian R, Gershwin, M. Eric, Akashi, Koichi

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AB0482 The cytotoxic effects of certolizumab pegol and golimumab mediated by transmembrane tumor necrosis factor α von Ueda, N., Tsukamoto, H., Mitoma, H., Ayano, M., Tanaka, A., Ohta, S.-I., Inoue, Y., Arinobu, Y., Niiro, H., Akashi, K., Horiuchi, T.

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AB0482 The cytotoxic effects of certolizumab pegol and golimumab mediated by transmembrane tumor necrosis factor [alpha] von Ueda, N, Tsukamoto, H, Mitoma, H, Ayano, M, Tanaka, A, Ohta, S-I, Inoue, Y, Arinobu, Y, Niiro, H, Akashi, K, Horiuchi, T

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Polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) in Japanese patients with systemic lupus erythematosus von Nakashima, H., Akahoshi, M., Tanaka, Y., Yamaoka, K., Ogami, E., Nagano, S., Arinobu, Y., Niiro, H., Otsuka, T., Niho, Y.

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