mTORC1 Controls Mitochondrial Activity and Biogenesis through 4E-BP-Dependent Translational Regulation von Morita, Masahiro, Gravel, Simon-Pierre, Chénard, Valérie, Sikström, Kristina, Zheng, Liang, Alain, Tommy, Gandin, Valentina, Avizonis, Daina, Arguello, Meztli, Zakaria, Chadi, McLaughlan, Shannon, Nouet, Yann, Pause, Arnim, Pollak, Michael, Gottlieb, Eyal, Larsson, Ola, St-Pierre, Julie, Topisirovic, Ivan, Sonenberg, Nahum

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A functional C-terminal TRAF3-binding site in MAVS participates in positive and negative regulation of the IFN antiviral response von Paz, Suzanne, Vilasco, Myriam, Werden, Steven J, Arguello, Meztli, Joseph-Pillai, Deshanthe, Zhao, Tiejun, Nguyen, Thi Lien-Anh, Sun, Qiang, Meurs, Eliane F, Lin, Rongtuan, Hiscott, John

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RIG-I-Mediated Antiviral Signaling Is Inhibited in HIV-1 Infection by a Protease-Mediated Sequestration of RIG-I von SOLIS, Mayra, NAKHAEI, Peyman, JALALIRAD, Mohammad, LACOSTE, Judith, DOUVILLE, Renée, ARGUELLO, Meztli, TIEJUN ZHAO, LAUGHREA, Michael, WAINBERG, Mark A, HISCOTT, John

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Translational control of ERK signaling through miRNA/4EHP-directed silencing von Jafarnejad, Seyed Mehdi, Chapat, Clément, Matta-Camacho, Edna, Gelbart, Idit Anna, Hesketh, Geoffrey G, Arguello, Meztli, Garzia, Aitor, Kim, Sung-Hoon, Attig, Jan, Shapiro, Maayan, Morita, Masahiro, Khoutorsky, Arkady, Alain, Tommy, Gkogkas, Christos G, Stern-Ginossar, Noam, Tuschl, Thomas, Gingras, Anne-Claude, Duchaine, Thomas F, Sonenberg, Nahum

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The 4E-BP-eIF4E axis promotes rapamycin-sensitive growth and proliferation in lymphocytes von So, Lomon, Lee, Jongdae, Palafox, Miguel, Mallya, Sharmila, Woxland, Chaz G, Arguello, Meztli, Truitt, Morgan L, Sonenberg, Nahum, Ruggero, Davide, Fruman, David A

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Systems analysis of a RIG-I agonist inducing broad spectrum inhibition of virus infectivity von Goulet, Marie-Line, Olagnier, David, Xu, Zhengyun, Paz, Suzanne, Belgnaoui, S Mehdi, Lafferty, Erin I, Janelle, Valérie, Arguello, Meztli, Paquet, Marilene, Ghneim, Khader, Richards, Stephanie, Smith, Andrew, Wilkinson, Peter, Cameron, Mark, Kalinke, Ulrich, Qureshi, Salman, Lamarre, Alain, Haddad, Elias K, Sekaly, Rafick Pierre, Peri, Suraj, Balachandran, Siddharth, Lin, Rongtuan, Hiscott, John

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Chemical targeting of the innate antiviral response by histone deacetylase inhibitors renders refractory cancers sensitive to viral oncolysis von Nguyên, Thi Lien-Anh, Abdelbary, Hesham, Arguello, Meztli, Breitbach, Caroline, Leveille, Simon, Diallo, Jean-Simon, Yasmeen, Amber, Bismar, Tarek A, Kirn, David, Falls, Theresa, Snoulten, Valerie E, Vanderhyden, Barbara C, Werier, Joel, Atkins, Harold, Vähä-Koskela, Markus J.V, Stojdl, David F, Bell, John C, Hiscott, John

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Polo-like Kinase 1 (PLK1) Regulates Interferon (IFN) Induction by MAVS von Vitour, Damien, Dabo, Stéphanie, Ahmadi Pour, Malek, Vilasco, Myriam, Vidalain, Pierre-Olivier, Jacob, Yves, Mezel-Lemoine, Mariana, Paz, Suzanne, Arguello, Meztli, Lin, Rongtuan, Tangy, Frédéric, Hiscott, John, Meurs, Eliane F.

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Ubiquitin-Regulated Recruitment of IκB Kinase ε to the MAVS Interferon Signaling Adapter von Paz, Suzanne, Vilasco, Myriam, Arguello, Meztli, Sun, Qiang, Lacoste, Judith, Nguyen, Thi Lien-Anh, Zhao, Tiejun, Shestakova, Elena A., Zaari, Scott, Bibeau-Poirier, Annie, Servant, Marc J., Lin, Rongtuan, Meurs, Eliane F., Hiscott, John

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HTLV-1 evades type I interferon antiviral signaling by inducing the suppressor of cytokine signaling 1 (SOCS1) von Olière, Stéphanie, Hernandez, Eduardo, Lézin, Agnès, Arguello, Meztli, Douville, Renée, Nguyen, Thi Lien-Anh, Olindo, Stéphane, Panelatti, Gérard, Kazanji, Mirdad, Wilkinson, Peter, Sékaly, Rafick-Pierre, Césaire, Raymond, Hiscott, John

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Ub surprised: viral ovarian tumor domain proteases remove ubiquitin and ISG15 conjugates von Arguello, Meztli D, Hiscott, John

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A CRM1-dependent Nuclear Export Pathway Is Involved in the Regulation of IRF-5 Subcellular Localization von Lin, Rongtuan, Yang, Long, Arguello, Meztli, Penafuerte, Claudia, Hiscott, John

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Vesicular Stomatitis Virus Oncolysis of T Lymphocytes Requires Cell Cycle Entry and Translation Initiation von OLIERE, Stephanie, ARGUELLO, Meztli, MESPLEDE, Thibault, TUMILASCI, Vanessa, NAKHAEI, Peyman, STOJDL, David, SONENBERG, Nahum, BELL, John, HISCOTT, John

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Disruption of the B-cell specific transcriptional program in HHV-8 associated primary effusion lymphoma cell lines von ARGUELLO, Meztli, SGARBANTI, Marco, HERNANDEZ, Eduardo, MAMANE, Yael, SHARMA, Sonia, SERVANT, Marc, RONGTUAN LIN, HISCOTT, John

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Correction: Systems Analysis of a RIG-I Agonist Inducing Broad Spectrum Inhibition of Virus Infectivity von Goulet, Marie-Line, Olagnier, David, Xu, Zhengyun, Paz, Suzanne, Belgnaoui, S Mehdi, Lafferty, Erin I, Janelle, Valérie, Arguello, Meztli, Paquet, Marilene, He, Zhong, Ghneim, Khader, Richards, Stephanie, Smith, Andrew, Wilkinson, Peter, Cameron, Mark, Kalinke, Ulrich, Qureshi, Salman, Lamarre, Alain, Haddad, Elias K, Sekaly, Rafick Pierre, Peri, Suraj, Balachandran, Siddharth, Lin, Rongtuan, Hiscott, John

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The NEMO adaptor bridges the nuclear factor-κB and interferon regulatory factor signaling pathways von Hiscott, John, Ballard, Dean W, Arguello, Meztli, Sun, Qiang, Zhao, Tiejun, Yang, Long, Lin, Rongtuan

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A requirement for NF-κB induction in the production of replication-competent HHV-8 virions von SGARBANTI, Marco, ARGUELLO, Meztli, TENOEVER, Benjamin R, BATTISTINI, Angela, RONGTUAN LIN, HISCOTT, John

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Abstract 45: BTM-3528 potently induces G1/G0 cell cycle arrest and is efficacious in preclinical models of diffuse large B-cell lymphoma von Kostura, Matthew, Levine, Jedd, Oza, Vibha, Cooper, Alan, Arguello, Meztli, White, Peter W., Ciblat, Stephane, Regina, Anthony, Bellavance, Edith, Brault, Martine, Siddiqui, Arshad, Luther, Michael

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Ubiquitin-Regulated Recruitment of IκB Kinase ɛ to the MAVS Interferon Signaling Adapter von Paz, Suzanne, Vilasco, Myriam, Arguello, Meztli, Sun, Qiang, Lacoste, Judith, Nguyen, Thi Lien-Anh, Zhao, Tiejun, Shestakova, Elena A., Zaari, Scott, Bibeau-Poirier, Annie, Servant, Marc J., Lin, Rongtuan, Meurs, Eliane F., Hiscott, John

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The eukaryotic translation initiation factor eIF4E is a direct transcriptional target of NF-κB and is aberrantly regulated in acute myeloid leukemia von Hariri, F, Arguello, M, Volpon, L, Culjkovic-Kraljacic, B, Nielsen, T H, Hiscott, J, Mann, K K, Borden, K L B

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