SELEX with modified nucleotides von Keefe, Anthony D, Cload, Sharon T

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Novel Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded Chemistry von Cuozzo, John W, Clark, Matthew A, Keefe, Anthony D, Kohlmann, Anna, Mulvihill, Mark, Ni, Haihong, Renzetti, Louis M, Resnicow, Daniel I, Ruebsam, Frank, Sigel, Eric A, Thomson, Heather A, Wang, Ce, Xie, Zhifeng, Zhang, Ying

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Machine Learning on DNA-Encoded Libraries: A New Paradigm for Hit Finding von McCloskey, Kevin, Sigel, Eric A, Kearnes, Steven, Xue, Ling, Tian, Xia, Moccia, Dennis, Gikunju, Diana, Bazzaz, Sana, Chan, Betty, Clark, Matthew A, Cuozzo, John W, Guié, Marie-Aude, Guilinger, John P, Huguet, Christelle, Hupp, Christopher D, Keefe, Anthony D, Mulhern, Christopher J, Zhang, Ying, Riley, Patrick

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Building oligonucleotide therapeutics using non-natural chemistries von Wilson, Charles, Keefe, Anthony D

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Bispecific Estrogen Receptor α Degraders Incorporating Novel Binders Identified Using DNA-Encoded Chemical Library Screening von Disch, Jeremy S, Duffy, Jennifer M, Lee, Esther C. Y, Gikunju, Diana, Chan, Betty, Levin, Benjamin, Monteiro, Michael I, Talcott, Sarah A, Lau, Anthony C, Zhou, Fei, Kozhushnyan, Anton, Westlund, Neil E, Mullins, Patrick B, Yu, Yan, von Rechenberg, Moritz, Zhang, Junyi, Arnautova, Yelena A, Liu, Yanbin, Zhang, Ying, McRiner, Andrew J, Keefe, Anthony D, Kohlmann, Anna, Clark, Matthew A, Cuozzo, John W, Huguet, Christelle, Arora, Shilpi

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Encoded Library Synthesis Using Chemical Ligation and the Discovery of sEH Inhibitors from a 334-Million Member Library von Litovchick, Alexander, Dumelin, Christoph E., Habeshian, Sevan, Gikunju, Diana, Guié, Marie-Aude, Centrella, Paolo, Zhang, Ying, Sigel, Eric A., Cuozzo, John W., Keefe, Anthony D., Clark, Matthew A.

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Novel Nucleic Acid Binding Small Molecules Discovered Using DNA-Encoded Chemistry von Litovchick, Alexander, Tian, Xia, Monteiro, Michael I, Kennedy, Kaitlyn M, Guié, Marie-Aude, Centrella, Paolo, Zhang, Ying, Clark, Matthew A, Keefe, Anthony D

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Functional proteins from a random-sequence library von Szostak, Jack W, Keefe, Anthony D

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Discovery of a Potent BTK Inhibitor with a Novel Binding Mode by Using Parallel Selections with a DNA‐Encoded Chemical Library von Cuozzo, John W., Centrella, Paolo A., Gikunju, Diana, Habeshian, Sevan, Hupp, Christopher D., Keefe, Anthony D., Sigel, Eric A., Soutter, Holly H., Thomson, Heather A., Zhang, Ying, Clark, Matthew A.

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Discovery of Nanomolar DCAF1 Small Molecule Ligands von Li, Alice Shi Ming, Kimani, Serah, Wilson, Brian, Noureldin, Mahmoud, González-Álvarez, Héctor, Mamai, Ahmed, Hoffer, Laurent, Guilinger, John P., Zhang, Ying, von Rechenberg, Moritz, Disch, Jeremy S., Mulhern, Christopher J., Slakman, Belinda L., Cuozzo, John W., Dong, Aiping, Poda, Gennady, Mohammed, Mohammed, Saraon, Punit, Mittal, Manish, Modh, Pratik, Rathod, Vaibhavi, Patel, Bhashant, Ackloo, Suzanne, Santhakumar, Vijayaratnam, Szewczyk, Magdalena M, Barsyte-Lovejoy, Dalia, Arrowsmith, Cheryl H., Marcellus, Richard, Guié, Marie-Aude, Keefe, Anthony D., Brown, Peter J., Halabelian, Levon, Al-awar, Rima, Vedadi, Masoud

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Discovery of Novel UDP‑N‑Acetylglucosamine Acyltransferase (LpxA) Inhibitors with Activity against Pseudomonas aeruginosa von Ryan, M. Dominic, Parkes, Alastair L, Corbett, David, Dickie, Anthony P, Southey, Michelle, Andersen, Ole A, Stein, Daniel B, Barbeau, Olivier R, Sanzone, Angelo, Thommes, Pia, Barker, John, Cain, Ricky, Compper, Christel, Dejob, Magali, Dorali, Alain, Etheridge, Donnya, Evans, Sian, Faulkner, Adele, Gadouleau, Elise, Gorman, Timothy, Haase, Denes, Holbrow-Wilshaw, Maisie, Krulle, Thomas, Li, Xianfu, Lumley, Christopher, Mertins, Barbara, Napier, Spencer, Odedra, Rajesh, Papadopoulos, Kostas, Roumpelakis, Vasileios, Spear, Kate, Trimby, Emily, Williams, Jennifer, Zahn, Michael, Keefe, Anthony D, Zhang, Ying, Soutter, Holly T, Centrella, Paolo A, Clark, Matthew A, Cuozzo, John W, Dumelin, Christoph E, Deng, Boer, Hunt, Avery, Sigel, Eric A, Troast, Dawn M, DeJonge, Boudewijn L. M

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Rational Design of Macrocyclic Noncovalent Inhibitors of SARS-CoV-2 M pro from a DNA-Encoded Chemical Library Screening Hit That Demonstrate Potent Inhibition against Pan-Coronavir... von Wang, Xu, Gotchev, Dimitar, Fan, Kristi Yi, Vega, Marvin M, Mani, Nagraj, McGovern-Gooch, Kayleigh, Cuconati, Andrea, Tercero, Breanna, Wang, Xiaohe, Carpino, Philip, Maskos, Klaus, Centrella, Paolo A, Schmitt, Andreas, Preuss, Franziska, Prasad, Archna, Chen, Chia-Yi, Clark, Matthew A, Guilinger, John P, Johnstone, Shawn, von König, Konstanze, Keefe, Anthony D, Liu, Jenny, Turcotte, Stéphane, Zhang, Ying, Konz Makino, Debora L, Lam, Angela M, Cole, Andrew G, Sofia, Michael J

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Development of Potent Mcl‑1 Inhibitors: Structural Investigations on Macrocycles Originating from a DNA-Encoded Chemical Library Screen von Hekking, Koen F. W., Maroto, Sergio, van Kekem, Kees, Haasjes, Frank S., Slootweg, Jack C., Oude Alink, Patrick G. B., Dirks, Ron, Sardana, Malvika, Bolster, Marjon G., Kuijpers, Brian, Smith, Dennis, Doodeman, Robin, Scheepstra, Marcel, Zech, Birgit, Mulvihill, Mark, Renzetti, Louis M., Babiss, Lee, Centrella, Paolo A., Clark, Matthew A., Cuozzo, John W., Guié, Marie-Aude, Sigel, Eric, Habeshian, Sevan, Hupp, Christopher D., Liu, Julie, Thomson, Heather A., Zhang, Ying, Keefe, Anthony D., Müller, Gerhard, Gremmen, Stijn

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Generating Selective Leads for Mer Kinase InhibitorsExample of a Comprehensive Lead-Generation Strategy von Nissink, J. Willem M, Bazzaz, Sana, Blackett, Carolyn, Clark, Matthew A, Collingwood, Olga, Disch, Jeremy S, Gikunju, Diana, Goldberg, Kristin, Guilinger, John P, Hardaker, Elizabeth, Hennessy, Edward J, Jetson, Rachael, Keefe, Anthony D, McCoull, William, McMurray, Lindsay, Olszewski, Allison, Overman, Ross, Pflug, Alexander, Preston, Marian, Rawlins, Philip B, Rivers, Emma, Schimpl, Marianne, Smith, Paul, Truman, Caroline, Underwood, Elizabeth, Warwicker, Juli, Winter-Holt, Jon, Woodcock, Simon, Zhang, Ying

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Discovery of Novel, Potent Inhibitors of Hydroxy Acid Oxidase 1 (HAO1) Using DNA-Encoded Chemical Library Screening von Lee, Esther C. Y, McRiner, Andrew J, Georgiadis, Katy E, Liu, Julie, Wang, Zooey, Ferguson, Andrew D, Levin, Benjamin, von Rechenberg, Moritz, Hupp, Christopher D, Monteiro, Michael I, Keefe, Anthony D, Olszewski, Allison, Eyermann, Charles J, Centrella, Paolo, Liu, Yanbin, Arora, Shilpi, Cuozzo, John W, Zhang, Ying, Clark, Matthew A, Huguet, Christelle, Kohlmann, Anna

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The Use of mRNA Display to Select High-Affinity Protein-Binding Peptides von Wilson, David S., Keefe, Anthony D., Szostak, Jack W.

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Identification and Evaluation of Reversible Covalent Binders to Cys55 of Bfl‑1 from a DNA-Encoded Chemical Library Screen von Lucas, Simon C. C., Blackwell, J. Henry, Börjesson, Ulf, Hargreaves, David, Milbradt, Alexander G., Ahmed, Samiyah, Bostock, Mark J., Guerot, Carine, Gohlke, Andrea, Kinzel, Olaf, Lamb, Michelle L., Selmi, Nidhal, Stubbs, Christopher J., Su, Nancy, Su, Qibin, Luo, Haiou, Xiong, Ting, Zuo, Xiaoqian, Bazzaz, Sana, Bienstock, Corey, Centrella, Paolo A., Denton, Kyle E., Gikunju, Diana, Guié, Marie-Aude, Guilinger, John P., Hupp, Christopher, Keefe, Anthony D., Satoh, Takashi, Zhang, Ying, Rivers, Emma L.

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Discovery of 2,4-1 H -Imidazole Carboxamides as Potent and Selective TAK1 Inhibitors von Veerman, Johan J N, Bruseker, Yorik B, Damen, Eddy, Heijne, Erik H, van Bruggen, Wendy, Hekking, Koen F W, Winkel, Rob, Hupp, Christopher D, Keefe, Anthony D, Liu, Julie, Thomson, Heather A, Zhang, Ying, Cuozzo, John W, McRiner, Andrew J, Mulvihill, Mark J, van Rijnsbergen, Peter, Zech, Birgit, Renzetti, Louis M, Babiss, Lee, Müller, Gerhard

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Corrigendum: Discovery of a Potent BTK Inhibitor with a Novel Binding Mode by Using Parallel Selections with a DNAEncoded Chemical Library von Cuozzo, John W., Centrella, Paolo A., Gikunju, Diana, Habeshian, Sevan, Hupp, Christopher D., Keefe, Anthony D., Sigel, Eric A., Soutter, Holly H., Thomson, Heather A., Zhang, Ying, Clark, Matthew A.

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Agonists and Antagonists of Protease-Activated Receptor 2 Discovered within a DNA-Encoded Chemical Library Using Mutational Stabilization of the Target von Brown, Dean G., Brown, Giles A., Centrella, Paolo, Certel, Kaan, Cooke, Robert M., Cuozzo, John W., Dekker, Niek, Dumelin, Christoph E., Ferguson, Andrew, Fiez-Vandal, Cédric, Geschwindner, Stefan, Guié, Marie-Aude, Habeshian, Sevan, Keefe, Anthony D., Schlenker, Oliver, Sigel, Eric A., Snijder, Arjan, Soutter, Holly T., Sundström, Linda, Troast, Dawn M., Wiggin, Giselle, Zhang, Jing, Zhang, Ying, Clark, Matthew A.

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