Targeting the Th17 pathway in psoriasis von Elloso, M Merle, Gomez-Angelats, Mireia, Fourie, Anne M

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The mode of action of IL-23 in experimental inflammatory arthritic pain and disease von Lee, Kevin M-C, Lupancu, Tanya, Chang, Leon, Manthey, Carl L, Zeeman, Martha, Fourie, Anne M, Hamilton, John A

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ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro von Golub, Suzanne B, Rogerson, Fraser M, Campbell, Ian K, East, Charlotte J, Lawlor, Kate E, Little, Christopher B, Fourie, Anne M, Fosang, Amanda J, Meeker, Clare T, Last, Karena, Stanton, Heather, Farmer, Pamela J

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Preclinical and clinical characterization of the RORγt inhibitor JNJ-61803534 von Xue, Xiaohua, De Leon-Tabaldo, Aimee, Luna-Roman, Rosa, Castro, Glenda, Albers, Michael, Schoetens, Freddy, DePrimo, Samuel, Devineni, Damayanthi, Wilde, Thomas, Goldberg, Steve, Kinzel, Olaf, Hoffmann, Thomas, Fourie, Anne M., Thurmond, Robin L.

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JNJ-77242113, a highly potent, selective peptide targeting the IL-23 receptor, provides robust IL-23 pathway inhibition upon oral dosing in rats and humans von Fourie, Anne M., Cheng, Xiaoli, Chang, Leon, Greving, Carrie, Li, Xinyi, Knight, Beverly, Polidori, David, Patrick, Aaron, Bains, Trpta, Steele, Ruth, Allen, Samantha J., Patch, Raymond J., Sun, Chengzao, Somani, Sandeep, Bhandari, Ashok, Liu, David, Huie, Keith, Li, Shu, Rodriguez, Michael A., Xue, Xiaohua, Kannan, Arun, Kosoglou, Teddy, Sherlock, Jonathan P., Towne, Jennifer, Holland, M. Claire, Modi, Nishit B.

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Author Correction: Preclinical and clinical characterization of the RORγt inhibitor JNJ-61803534 von Xue, Xiaohua, De Leon-Tabaldo, Aimee, Luna-Roman, Rosa, Castro, Glenda, Albers, Michael, Schoetens, Freddy, DePrimo, Samuel, Devineni, Damayanthi, Wilde, Thomas, Goldberg, Steve, Kinzel, Olaf, Hoffmann, Thomas, Fourie, Anne M., Thurmond, Robin L.

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Leukotriene B4 Receptors BLT1 and BLT2: Expression and Function in Human and Murine Mast Cells von Lundeen, Katherine A, Sun, Binggang, Karlsson, Lars, Fourie, Anne M

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Catalytic Activity of ADAM8, ADAM15, and MDC-L (ADAM28) on Synthetic Peptide Substrates and in Ectodomain Cleavage of CD23 von Fourie, Anne M., Coles, Fawn, Moreno, Veronica, Karlsson, Lars

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Single-cell RNA sequencing of psoriatic skin identifies pathogenic Tc17 cell subsets and reveals distinctions between CD8+ T cells in autoimmunity and cancer von Liu, Jared, Chang, Hsin-Wen, Huang, Zhi-Ming, Nakamura, Mio, Sekhon, Sahil, Ahn, Richard, Munoz-Sandoval, Priscila, Bhattarai, Shrishti, Beck, Kristen M., Sanchez, Isabelle M., Yang, Eric, Pauli, Mariela, Arron, Sarah T., Fung-Leung, Wai-Ping, Munoz, Ernesto, Liu, Xuejun, Bhutani, Tina, North, Jeffrey, Fourie, Anne M., Rosenblum, Michael D., Liao, Wilson

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IL-23 regulation of myeloid cell biology during inflammation von Lee, Kevin M.-C., Lupancu, Tanya, Chang, Leon, Manthey, Carl L., Zeeman, Martha, Fourie, Anne M., Hamilton, John A.

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Pharmacologic modulation of RORγt translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis von Xue, Xiaohua, Soroosh, Pejman, De Leon-Tabaldo, Aimee, Luna-Roman, Rosa, Sablad, Marciano, Rozenkrants, Natasha, Yu, Jingxue, Castro, Glenda, Banie, Homayon, Fung-Leung, Wai-Ping, Santamaria-Babi, Luis, Schlueter, Thomas, Albers, Michael, Leonard, Kristi, Budelsky, Alison L., Fourie, Anne M.

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Identification of benzofuran central cores for the inhibition of leukotriene A4 hydrolase von Eccles, Wendy, Blevitt, Jonathan M., Booker, Jamila N., Chrovian, Christa C., Crawford, Shelby, de Leon, Aimee Rose, Deng, Xiaohu, Fourie, Anne M., Grice, Cheryl A., Herman, Krystal, Karlsson, Lars, Kearney, Aaron M., Lee-Dutra, Alice, Liang, Jimmy, Luna, Rosa, Pippel, Dan, Rao, Navin, Riley, Jason P., Santillán, Alejandro, Savall, Brad, Tanis, Virginia M., Xue, Xiaohua, Young, Arlene L.

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Optimization and biological evaluation of thiazole-bis-amide inverse agonists of RORγt von Gege, Christian, Albers, Michael, Kinzel, Olaf, Kleymann, Gerald, Schlüter, Thomas, Steeneck, Christoph, Hoffmann, Thomas, Xue, Xiaohua, Cummings, Maxwell D., Spurlino, John, Milligan, Cynthia, Fourie, Anne M., Edwards, James P., Leonard, Kristi, Coe, Kevin, Scott, Brian, Pippel, Dan, Goldberg, Steven D.

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Discovery and optimization of new oxadiazole substituted thiazole RORγt inverse agonists through a bioisosteric amide replacement approach von Steeneck, Christoph, Gege, Christian, Kinzel, Olaf, Albers, Michael, Kleymann, Gerald, Schlüter, Thomas, Schulz, Andreas, Xue, Xiaohua, Cummings, Maxwell D., Fourie, Anne M., Leonard, Kristi A., Scott, Brian, Edwards, James P., Hoffmann, Thomas, Goldberg, Steven D.

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Identification and structure activity relationships of quinoline tertiary alcohol modulators of RORγt von Kummer, David A., Cummings, Maxwell D., Abad, Marta, Barbay, Joseph, Castro, Glenda, Wolin, Ronald, Kreutter, Kevin D., Maharoof, Umar, Milligan, Cynthia, Nishimura, Rachel, Pierce, Joan, Schalk-Hihi, Celine, Spurlino, John, Urbanski, Maud, Venkatesan, Hariharan, Wang, Aihua, Woods, Craig, Xue, Xiaohua, Edwards, James P., Fourie, Anne M., Leonard, Kristi

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6-Substituted quinolines as RORγt inverse agonists von Barbay, J. Kent, Cummings, Maxwell D., Abad, Marta, Castro, Glenda, Kreutter, Kevin D., Kummer, David A., Maharoof, Umar, Milligan, Cynthia, Nishimura, Rachel, Pierce, Joan, Schalk-Hihi, Celine, Spurlino, John, Tanis, Virginia M., Urbanski, Maud, Venkatesan, Hariharan, Wang, Aihua, Woods, Craig, Wolin, Ronald, Xue, Xiaohua, Edwards, James P., Fourie, Anne M., Leonard, Kristi

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3-Substituted Quinolines as RORγt Inverse Agonists von Tanis, Virginia M., Venkatesan, Hariharan, Cummings, Maxwell D., Albers, Michael, Kent Barbay, J., Herman, Krystal, Kummer, David A., Milligan, Cynthia, Nelen, Marina I., Nishimura, Rachel, Schlueter, Thomas, Scott, Brian, Spurlino, John, Wolin, Ronald, Woods, Craig, Xue, Xiaohua, Edwards, James P., Fourie, Anne M., Leonard, Kristi

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Leukotriene A(4) hydrolase inhibition attenuates allergic airway inflammation and hyperresponsiveness von Rao, Navin L, Riley, Jason P, Banie, Homayon, Xue, Xiaohua, Sun, Binggang, Crawford, Shelby, Lundeen, Katherine A, Yu, Fuqu, Karlsson, Lars, Fourie, Anne M, Dunford, Paul J

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Leukotriene A4 Hydrolase Inhibition Attenuates Allergic Airway Inflammation and Hyperresponsiveness von RAO, Navin L, RILEY, Jason P, DUNFORD, Paul J, BANIE, Homayon, XIAOHUA XUE, BINGGANG SUN, CRAWFORD, Shelby, LUNDEEN, Katherine A, FUQU YU, KARLSSON, Lars, FOURIE, Anne M

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Identification of benzofuran central cores for the inhibition of leukotriene A(4) hydrolase von Eccles, Wendy, Blevitt, Jonathan M, Booker, Jamila N, Chrovian, Christa C, Crawford, Shelby, de Leon, Aimee Rose, Deng, Xiaohu, Fourie, Anne M, Grice, Cheryl A, Herman, Krystal, Karlsson, Lars, Kearney, Aaron M, Lee-Dutra, Alice, Liang, Jimmy, Luna, Rosa, Pippel, Dan, Rao, Navin, Riley, Jason P, Santillán, Alejandro, Savall, Brad, Tanis, Virginia M, Xue, Xiaohua, Young, Arlene L

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