Structure, Function, and Therapeutic Use of IgM Antibodies von Keyt, Bruce A., Baliga, Ramesh, Sinclair, Angus M., Carroll, Stephen F., Peterson, Marvin S.

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Glycoengineering: The effect of glycosylation on the properties of therapeutic proteins von Sinclair, Angus M., Elliott, Steve

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The effect of erythropoietin on normal and neoplastic cells von Elliott, Steve, Sinclair, Angus M

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The Broad Anti-AML Activity of the CD33/CD3 BiTE Antibody Construct, AMG 330, Is Impacted by Disease Stage and Risk von Harrington, Kimberly H, Gudgeon, Chelsea J, Laszlo, George S, Newhall, Kathryn J, Sinclair, Angus M, Frankel, Stanley R, Kischel, Roman, Chen, Guang, Walter, Roland B

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Cellular determinants for preclinical activity of a novel CD33/CD3 bispecific T-cell engager (BiTE) antibody, AMG 330, against human AML von Laszlo, George S., Gudgeon, Chelsea J., Harrington, Kimberly H., Dell'Aringa, Justine, Newhall, Kathryn J., Means, Gary D., Sinclair, Angus M., Kischel, Roman, Frankel, Stanley R., Walter, Roland B.

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Multimeric Anti-DR5 IgM Agonist Antibody IGM-8444 Is a Potent Inducer of Cancer Cell Apoptosis and Synergizes with Chemotherapy and BCL-2 Inhibitor ABT-199 von Wang, Beatrice T, Kothambawala, Tasnim, Wang, Ling, Matthew, Thomas J, Calhoun, Susan E, Saini, Avneesh K, Kotturi, Maya F, Hernandez, Genevive, Humke, Eric W, Peterson, Marvin S, Sinclair, Angus M, Keyt, Bruce A

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Kidney-Specific Inactivation of the KIF3A Subunit of Kinesin-II Inhibits Renal Ciliogenesis and Produces Polycystic Kidney Disease von Lin, Fangming, Hiesberger, Thomas, Cordes, Kimberly, Sinclair, Angus M., Lawrence S. B. Goldstein, Somlo, Stefan, Igarashi, Peter

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Functional erythropoietin receptor is undetectable in endothelial, cardiac, neuronal, and renal cells von Sinclair, Angus M., Coxon, Angela, McCaffery, Ian, Kaufman, Stephen, Paweletz, Katherine, Liu, Liqin, Busse, Leigh, Swift, Susan, Elliott, Steven, Begley, C. Glenn

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Erythropoiesis stimulating agents : approaches to modulate activity von Sinclair, Angus M

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Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies von Raman, Swetha, Beilschmidt, Melissa, To, Minh, Lin, Kevin, Lui, Francine, Jmeian, Yazen, Ng, Mark, Fernandez, Minerva, Fu, Ying, Mascall, Keith, Duque, Alejandro, Wang, Xiaowei, Pan, Guohua, Angers, Stephane, Moffat, Jason, Sidhu, Sachdev S., Magram, Jeanne, Sinclair, Angus M., Fransson, Johan, Julien, Jean-Philippe

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Absence of functional EpoR expression in human tumor cell lines von Swift, Susan, Ellison, Aaron R., Kassner, Paul, McCaffery, Ian, Rossi, John, Sinclair, Angus M., Begley, C. Glenn, Elliott, Steven

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Anti-Epo receptor antibodies do not predict Epo receptor expression von Elliott, Steve, Busse, Leigh, Bass, Michael B., Lu, Hsieng, Sarosi, Ildiko, Sinclair, Angus M., Spahr, Chris, Um, Moonkyoung, Van, Gwyneth, Begley, C. Glenn

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Romiplostim promotes platelet recovery in a mouse model of multicycle chemotherapy-induced thrombocytopenia von McElroy, Patricia L, Wei, Ping, Buck, Keri, Sinclair, Angus M, Eschenberg, Michael, Sasu, Barbra, Molineux, Graham

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Expression and function of erythropoietin receptors in tumors : Implications for the use of erythropoiesis-stimulating agents in cancer patients von SINCLAIR, Angus M, TODD, Marque D, FORSYTHE, Kevin, KNOX, Susan J, ELLIOTT, Steve, BEGLEY, C. Glenn

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Connection Between B Lymphocyte and Osteoclast Differentiation Pathways von Manabe, Noriyo, Kawaguchi, Hiroshi, Chikuda, Hirotaka, Miyaura, Chisato, Inada, Masaki, Nagai, Ryozo, Nabeshima, Yo-ichi, Nakamura, Kozo, Sinclair, Angus M, Scheuermann, Richard H, Kuro-o, Makoto

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1078 Agonistic CD40 IgM antibodies enhance immune responses beyond that of IgGs von Tartey, Sarang, Narayanaswamy, Vignesh, Pandya, Deepal, Krishnoji Rao, Vidhya Bai, Perez, Elizabeth, Hinton, Paul, Ng, Dean, Muchhal, Umesh, Keyt, Bruce, Sinclair, Angus, Phee, Hyewon

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Characterization of Bispecific T-cell Engager (BiTE®) Antibodies with a High-Capacity T-cell Dependent Cellular Cytotoxicity (TDCC) Assay von Nazarian, Aaron A., Archibeque, Ivonne L., Nguyen, Yen H., Wang, Paul, Sinclair, Angus M., Powers, David A.

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1174 Costimulatory IgM T-cell engagers with enhanced and durable cytotoxicity von Li, Keyu, Xue, Jie, Pandya, Deepal, Yakkundi, Poonam, Li, Gene, Mai, Kristene, Hanna, Nardeen, Ye, Zhongde, Rosete, Rodnie, Wang, Jinqiu, Mao, Tina, Krishnoji Rao, Vidhya Bai, Perez, Elizabeth, Chudasama, Palak, Wang, Yue, Rahman, Sachi, Malik, Zee, Hinton, Paul, Bzymek, Krzysztof, Keyt, Bruce, Liu, Liqin, Sinclair, Angus, Muchhal, Umesh

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711 IGM-7354 is an anti-PD-L1 IgM antibody and IL-15 cytokine fusion that enhances NK and CD8+ T cell proliferation and tumor cytotoxicity plus potently reverses T cell exhaustion... von Giffon, Thierry, Desbois, Melanie, Ng, Dean, Yakkundi, Poonam, Manlusoc, Marigold, Oyasu, Miho, Rosete, Rodnie, Machado, Daniel, Calhoun, Susan, Kothambawala, Tasnim, Saini, Avneesh, Wang, Beatrice, Kotturi, Maya, Keyt, Bruce, Sinclair, Angus

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908 Humanized model for assessment of therapies targeting either lymphoid or myeloid compartment: enhanced evaluation of clinical relevancy & translatability von Renart-Depontieu, Florence, Martin, Gaëlle, Beuraud, Chloé, Yakkundi, Poonam, Sinclair, Angus, Denis, Morgane, Magadoux, Léa, Kress, Elsa, Dumontet, Charles, Bourre, Ludovic, Campbell, Dean, Doerner, Astrid, Isnard-Petit, Patricia, Fraichard, Alexandre, Cherifi, Yacine, Thiam, Kader

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