Progress towards a public chemogenomic set for protein kinases and a call for contributions von Drewry, David H, Wells, Carrow I, Andrews, David M, Angell, Richard, Al-Ali, Hassan, Axtman, Alison D, Capuzzi, Stephen J, Elkins, Jonathan M, Ettmayer, Peter, Frederiksen, Mathias, Gileadi, Opher, Gray, Nathanael, Hooper, Alice, Knapp, Stefan, Laufer, Stefan, Luecking, Ulrich, Michaelides, Michael, Müller, Susanne, Muratov, Eugene, Denny, R Aldrin, Saikatendu, Kumar S, Treiber, Daniel K, Zuercher, William J, Willson, Timothy M

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Structure–activity relationships for the G-quadruplex-targeting experimental drug QN-302 and two analogues probed with comparative transcriptome profiling and molecular modeling von Ahmed, Ahmed Abdullah, Chen, Shuang, Roman-Escorza, Maria, Angell, Richard, Oxenford, Sally, McConville, Matthew, Barton, Naomi, Sunose, Mihiro, Neidle, Dan, Haider, Shozeb, Arshad, Tariq, Neidle, Stephen

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Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion von Cockerill, G. Stuart, Angell, Richard M, Bedernjak, Alexandre, Chuckowree, Irina, Fraser, Ian, Gascon-Simorte, Jose, Gilman, Morgan S. A, Good, James A. D, Harland, Rachel, Johnson, Sara M, Ludes-Meyers, John H, Littler, Edward, Lumley, James, Lunn, Graham, Mathews, Neil, McLellan, Jason S, Paradowski, Michael, Peeples, Mark E, Scott, Claire, Tait, Dereck, Taylor, Geraldine, Thom, Michelle, Thomas, Elaine, Villalonga Barber, Carol, Ward, Simon E, Watterson, Daniel, Williams, Gareth, Young, Paul, Powell, Kenneth

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The crystal structure of NS5A domain 1 from genotype 1a reveals new clues to the mechanism of action for dimeric HCV inhibitors von Lambert, Sebastian M., Langley, David R., Garnett, James A., Angell, Richard, Hedgethorne, Katy, Meanwell, Nicholas A., Matthews, Steve J.

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Regulation of metastasis suppressor NME1 by a key metabolic cofactor coenzyme A von Yu, Bess Yi Kun, Tossounian, Maria-Armineh, Hristov, Stefan Denchev, Lawrence, Ryan, Arora, Pallavi, Tsuchiya, Yugo, Peak-Chew, Sew Yeu, Filonenko, Valeriy, Oxenford, Sally, Angell, Richard, Gouge, Jerome, Skehel, Mark, Gout, Ivan

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Identification of Broad-Spectrum Antiviral Compounds by Targeting Viral Entry von Mazzon, Michela, Ortega-Prieto, Ana Maria, Imrie, Douglas, Luft, Christin, Hess, Lena, Czieso, Stephanie, Grove, Joe, Skelton, Jessica Katy, Farleigh, Laura, Bugert, Joachim J, Wright, Edward, Temperton, Nigel, Angell, Richard, Oxenford, Sally, Jacobs, Michael, Ketteler, Robin, Dorner, Marcus, Marsh, Mark

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Asymmetrically Substituted Quadruplex-Binding Naphthalene Diimide Showing Potent Activity in Pancreatic Cancer Models von Ahmed, Ahmed A, Angell, Richard, Oxenford, Sally, Worthington, Jenny, Williams, Nicole, Barton, Naomi, Fowler, Thomas G, O’Flynn, Daniel E, Sunose, Mihiro, McConville, Matthew, Vo, Tam, Wilson, W. David, Karim, Saadia A, Morton, Jennifer P, Neidle, Stephen

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Development and validation of RdRp Screen, a crystallization screen for viral RNA-dependent RNA polymerases von Riccio, Federica, Talapatra, Sandeep K, Oxenford, Sally, Angell, Richard, Mazzon, Michela, Kozielski, Frank

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Biphenyl amide p38 kinase inhibitors 4: DFG-in and DFG-out binding modes von Angell, Richard M., Angell, Tony D., Bamborough, Paul, Bamford, Mark J., Chung, Chun-wa, Cockerill, Stuart G., Flack, Stephen S., Jones, Katherine L., Laine, Dramane I., Longstaff, Timothy, Ludbrook, Steve, Pearson, Rosannah, Smith, Kathryn J., Smee, Penny A., Somers, Don O., Walker, Ann L.

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Development of a Fluorescence Intensity Assay for the Mitotic Serine/Threonine Protein Kinase Aurora-A von Slatter, Andrew F., Campbell, Spencer, Angell, Richard M.

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N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3 von Angell, Richard M., Atkinson, Francis L., Brown, Murray J., Chuang, Tsu Tshen, Christopher, John A., Cichy-Knight, Maria, Dunn, Allison K., Hightower, Kendra E., Malkakorpi, Susanna, Musgrave, James R., Neu, Margarete, Rowland, Paul, Shea, Robyn L., Smith, Jeffery L., Somers, Donald O., Thomas, Sonia A., Thompson, Gladstone, Wang, Ruolan

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Biphenyl amide p38 kinase inhibitors 1: Discovery and binding mode von Angell, Richard M., Bamborough, Paul, Cleasby, Anne, Cockerill, Stuart G., Jones, Katherine L., Mooney, Christopher J., Somers, Donald O., Walker, Ann L.

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Selective Plasma Hydrolysis of Glucocorticoid γ-Lactones and Cyclic Carbonates by the Enzyme Paraoxonase: An Ideal Plasma Inactivation Mechanism von Biggadike, Keith, Angell, Richard M, Burgess, Colin M, Farrell, Rosanne M, Hancock, Ashley P, Harker, Andy J, Irving, Wendy R, Ioannou, Chris, Procopiou, Panayiotis A, Shaw, Rupert E, Solanke, Yemisi E, Singh, Onkar M. P, Snowden, Michael A, Stubbs, Rob J, Walton, Sarah, Weston, Helen E

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Biphenyl amide p38 kinase inhibitors 2: Optimisation and SAR von Angell, Richard M., Angell, Tony D., Bamborough, Paul, Brown, David, Brown, Murray, Buckton, Jacky B., Cockerill, Stuart G., Edwards, Chris D., Jones, Katherine L., Longstaff, Tim, Smee, Penny A., Smith, Kathryn J., Somers, Don O., Walker, Ann L., Willson, Malcolm

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N-4-Pyrimidinyl-1H-indazol-4-amine inhibitors of Lck: Indazoles as phenol isosteres with improved pharmacokinetics von Bamborough, Paul, Angell, Richard M., Bhamra, Inder, Brown, David, Bull, James, Christopher, John A., Cooper, Anthony W.J., Fazal, Lynsey H., Giordano, Ilaria, Hind, Lucy, Patel, Vipulkumar K., Ranshaw, Lisa E., Sims, Martin J., Skone, Philip A., Smith, Kathryn J., Vickerstaff, Emma, Washington, Melanie

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Catalog of the Isidore Witmark collection of autographed books and musical scores in the Columbia University Libraries von Columbia University. Libraries

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[YIA] Regulation of metastasis suppressor NME1 by a key metabolic cofactor coenzyme A von Kun Yu, Bess Yi, Tossounian, Maria-Armineh, Hristov, Stefan Denchev, Arora, Pallavi, Tsuchiyaugo, Yugo, Peak-Chew, Sew Yeu, Oxenford, Sally, Angell, Richard, Gouge, Jerome, Skehel, Mark, Gout, Ivan

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A small-molecule PI3Kα activator for cardioprotection and neuroregeneration von Gong, Grace Q., Bilanges, Benoit, Allsop, Ben, Masson, Glenn R., Roberton, Victoria, Askwith, Trevor, Oxenford, Sally, Madsen, Ralitsa R., Conduit, Sarah E., Bellini, Dom, Fitzek, Martina, Collier, Matt, Najam, Osman, He, Zhenhe, Wahab, Ben, McLaughlin, Stephen H., Chan, A. W. Edith, Feierberg, Isabella, Madin, Andrew, Morelli, Daniele, Bhamra, Amandeep, Vinciauskaite, Vanesa, Anderson, Karen E., Surinova, Silvia, Pinotsis, Nikos, Lopez-Guadamillas, Elena, Wilcox, Matthew, Hooper, Alice, Patel, Chandni, Whitehead, Maria A., Bunney, Tom D., Stephens, Len R., Hawkins, Phillip T., Katan, Matilda, Yellon, Derek M., Davidson, Sean M., Smith, David M., Phillips, James B., Angell, Richard, Williams, Roger L., Vanhaesebroeck, Bart

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Abstract 4069: The potent quadruplex-binding compound SOP1812 shows anti-tumor activity in patient-derived in vivo models of pancreatic cancer von Neidle, Stephen, Ahmed, Ahmed, Angell, Richard, Oxenford, Sally

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Regulation of metastasis suppressor NME1 by a key metabolic cofactor coenzyme A von Kun Yu, Bess Yi, Tossounian, Maria-Armineh, Hristov, Stefan Denchev, Lawrence, Ryan, Arora, Pallavi, Tsuchiya, Yugo, Peak-Chew, Sew Yeu, Oxenford, Sally, Angell, Richard, Gouge, Jerome, Skehel, Mark, Gout, Ivan

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