Passive Membrane Permeability of Macrocycles Can Be Controlled by Exocyclic Amide Bonds von Hickey, Jennifer L, Zaretsky, Serge, St. Denis, Megan A, Kumar Chakka, Sai, Morshed, M. Monzur, Scully, Conor C. G, Roughton, Andrew L, Yudin, Andrei K

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Structure–activity studies of a novel series of isoxazole-3-carboxamide derivatives as TRPV1 antagonists von Palin, Ronald, Abernethy, Lynn, Ansari, Nasrin, Cameron, Kenneth, Clarkson, Tom, Dempster, Maureen, Dunn, David, Easson, Anna-Marie, Edwards, Darren, Maclean, John, Everett, Katy, Feilden, Helen, Ho, Koc-Kan, Kultgen, Steve, Littlewood, Peter, McArthur, Duncan, McGregor, Deborah, McLuskey, Hazel, Neagu, Irina, Neale, Stuart, Nisbet, Lesley-Anne, Ohlmeyer, Michael, Pham, Quynhchi, Ratcliffe, Paul, Rong, Yajing, Roughton, Andrew, Sammons, Melanie, Swanson, Robert, Tracey, Heather, Walker, Glenn

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Triazine and pyrimidine based ROCK inhibitors with efficacy in spontaneous hypertensive rat model von Ho, Koc-Kan, Beasley, James R., Belanger, Laura, Black, Darcey, Chan, Jui-Hsiang, Dunn, David, Hu, Bing, Klon, Anthony, Kultgen, Steven G., Ohlmeyer, Michael, Parlato, Susan M., Ray, Peter C., Pham, Quynhchi, Rong, Yajing, Roughton, Andrew L., Walker, Tiffany L., Wright, Jane, Xu, Kai, Xu, Yan, Zhang, Limei, Webb, Maria

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Nonionic Analogs of RNA with Dimethylene Sulfone Bridges von Richert, Clemens, Roughton, Andrew L, Benner, Steven A

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Predicting cyclic peptide chemical shifts using quantum mechanical calculations von Zaretsky, Serge, Hickey, Jennifer L., St. Denis, Megan A., Scully, Conor C.G., Roughton, Andrew L., Tantillo, Dean J., Lodewyk, Michael W., Yudin, Andrei K.

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Crystal Structure of a Dimethylene Sulfone-Linked Ribodinucleotide Analog von Roughton, Andrew L, Portmann, Stefan, Benner, Steven A, Egli, Martin

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Identification of NAE Inhibitors Exhibiting Potent Activity in Leukemia Cells: Exploring the Structural Determinants of NAE Specificity von Lukkarila, Julie L., da Silva, Sara R., Ali, Mohsin, Shahani, Vijay M., Xu, G. Wei, Berman, Judd, Roughton, Andrew, Dhe-Paganon, Sirano, Schimmer, Aaron D., Gunning, Patrick T.

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Cyclization of protected N-acylhydroxyguanidine to 3-amino-1,2,4-oxadiazole von Côté, Jamie B., Roughton, Andrew, Nasielski, Joanna, Wilson, Jeff, You, Ji Chang, Berman, Judd M.

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Discovery of potent, soluble and orally active TRPV1 antagonists. Structure–activity relationships of a series of isoxazoles von Ratcliffe, Paul, Abernethy, Lynn, Ansari, Nasrin, Cameron, Ken, Clarkson, Tom, Dempster, Maureen, Dunn, David, Easson, Anna-Marie, Edwards, Darren, Everett, Katy, Feilden, Helen, Ho, Koc-Kan, Kultgen, Steve, Littlewood, Peter, Maclean, John, McArthur, Duncan, McGregor, Deborah, McLuskey, Hazel, Neagu, Irina, Nimz, Olaf, Nisbet, Lesley-Anne, Ohlmeyer, Michael, Palin, Ronnie, Pham, Quynhchi, Rong, Yajing, Roughton, Andrew, Sammons, Melanie, Swanson, Robert, Tracey, Heather, Walker, Glenn

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Efficient chiral crystallization and asymmetric synthesis via a solid-state di-.pi.-methane-type photorearrangement von Roughton, Andrew L, Muneer, Mohammad, Demuth, Martin, Klopp, Ingo, Krueger, Carl

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Imidazolylpyrimidine based CXCR2 chemokine receptor antagonists von Ho, Koc-Kan, Auld, Douglas S., Bohnstedt, Adolph C., Conti, Paolo, Dokter, Wim, Erickson, Shawn, Feng, Daming, Inglese, Jim, Kingsbury, Celia, Kultgen, Steven G., Liu, Rong-Qiang, Masterson, Christopher M., Ohlmeyer, Michael, Rong, Yajing, Rooseboom, Martijn, Roughton, Andrew, Samama, Philippe, Smit, Martin-Jan, Son, Ellen, van der Louw, Jaap, Vogel, Gerard, Webb, Maria, Wijkmans, Jac, You, Ming

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Stereocontrolled construction of 1,7-dimethyl A.B.C.[6.6.6] tricycles. Part I. Transannular Diels-Alder reactions of 14-membered macrocycles containing trans-dienophiles von Xu, Yao-Chang, Roughton, Andrew L, Plante, Raymond, Goldstein, Solo, Deslongchamps, Pierre

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Stereocontrolled construction of 1,7-dimethyl A.B.C.[6.6.6] tricycles. Part II. Transannular Diels-Alder reaction of 14-membered macrocycles containing cis-dienophiles von Xu, Yao-Chang, Roughton, Andrew L, Soucy, Pierre, Goldstein, Solo, Deslongchamps, Pierre

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COMPOSITIONS AND METHODS FOR INHIBITION OF EXPRESSION OF ANGIOTENSINOGEN (AGT) GENES von FANG, Zhou, ZHANG, Tianbu, MONTERO, Saul Martinez, ROUGHTON, Andrew L, LIN, Luping, PARATHATH, Sajesh, YANG, Jing

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Cyclic peptides multimers targeting α4β7 integrin von Vazquez, Manuel Perez, Chakka, Sai Kumar, Morshed, Mohammed Monzur, Roughton, Andrew, Hickey, Jennifer L, Patel, Narendrakumar B, Kafal, Adam Paul

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CYCLIC PEPTIDES MULTIMERS TARGETING ALPHA-4-BETA-7 INTEGRIN von KAFAL, Adam Paul, PATEL, Narendrakumar B, ROUGHTON, Andrew, MORSHED, Mohammed Monzur, HICKEY, Jennifer L, VAZQUEZ, Manuel Perez, CHAKKA, Sai Kumar

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COMPOUNDS TARGETING ALPHA4-BETA7 INTEGRIN von Vazquez, Manuel Perez, Chakka, Sai Kumar, Roughton, Andrew, Morshed, Monzur, Hickey, Jennifer, Patel, Narendrakumar, Kafal, Adam Paul

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Cyclic peptides multimers targeting α-4-β-7 integrin von Vazquez, Manuel Perez, Chakka, Sai Kumar, Morshed, Mohammed Monzur, Roughton, Andrew, Hickey, Jennifer L, Patel, Narendrakumar B, Kafal, Adam Paul

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COMPOUNDS TARGETING ALPHA4-BETA7 INTEGRIN von KAFAL, Adam Paul, ROUGHTON, Andrew, HICKEY, Jennifer, VAZQUEZ, Manuel Perez, CHAKKA, Sai Kumar, MORSHED, Monzur, PATEL, Narendrakumar

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Homodetic cyclic peptides targeting alpha-4-beta-7 integrin von Vazquez, Manuel Perez, Morshed, M. Monzur, Roughton, Andrew, Hickey, Jennifer L, Kafal, Adam Paul

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