Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancers by dNTP Starvation von Pfister, Sophia X., Markkanen, Enni, Jiang, Yanyan, Sarkar, Sovan, Woodcock, Mick, Orlando, Giulia, Mavrommati, Ioanna, Pai, Chen-Chun, Zalmas, Lykourgos-Panagiotis, Drobnitzky, Neele, Dianov, Grigory L., Verrill, Clare, Macaulay, Valentine M., Ying, Songmin, La Thangue, Nicholas B., D’Angiolella, Vincenzo, Ryan, Anderson J., Humphrey, Timothy C.

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Vandetanib in Patients With Locally Advanced or Metastatic Medullary Thyroid Cancer: A Randomized, Double-Blind Phase III Trial von WELLS, Samuel A, ROBINSON, Bruce G, READ, Jessica, LANGMUIR, Peter, RYAN, Anderson J, SCHLUMBERGER, Martin J, GAGEL, Robert F, DRALLE, Henning, FAGIN, James A, SANTORO, Massimo, BAUDIN, Eric, ELISEI, Rossella, JARZAB, Barbara, VASSELLI, James R

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Replication Stress and Chromatin Context Link ATM Activation to a Role in DNA Replication von Olcina, Monica M., Foskolou, Iosifina P., Anbalagan, Selvakumar, Senra, Joana M., Pires, Isabel M., Jiang, Yanyan, Ryan, Anderson J., Hammond, Ester M.

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Selective DNA-PKcs inhibition extends the therapeutic index of localized radiotherapy and chemotherapy von Willoughby, Catherine E, Jiang, Yanyan, Thomas, Huw D, Willmore, Elaine, Kyle, Suzanne, Wittner, Anita, Phillips, Nicole, Zhao, Yan, Tudhope, Susan J, Prendergast, Lisa, Junge, Gesa, Lourenco, Luiza Madia, Finlay, M Raymond V, Turner, Paul, Munck, Joanne M, Griffin, Roger J, Rennison, Tommy, Pickles, James, Cano, Celine, Newell, David R, Reeves, Helen L, Ryan, Anderson J, Wedge, Stephen R

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Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response von Zhang, Ping, Kitchen-Smith, Isaac, Xiong, Lingyun, Stracquadanio, Giovanni, Brown, Katherine, Richter, Philipp H, Wallace, Marsha D, Bond, Elisabeth, Sahgal, Natasha, Moore, Samantha, Nornes, Svanhild, De Val, Sarah, Surakhy, Mirvat, Sims, David, Wang, Xuting, Bell, Douglas A, Zeron-Medina, Jorge, Jiang, Yanyan, Ryan, Anderson J, Selfe, Joanna L, Shipley, Janet, Kar, Siddhartha, Pharoah, Paul D, Loveday, Chey, Jansen, Rick, Grochola, Lukasz F, Palles, Claire, Protheroe, Andrew, Millar, Val, Ebner, Daniel V, Pagadala, Meghana, Blagden, Sarah P, Maughan, Timothy S, Domingo, Enric, Tomlinson, Ian, Turnbull, Clare, Carter, Hannah, Bond, Gareth L

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Overcoming acquired resistance to HSP90 inhibition by targeting JAK-STAT signalling in triple-negative breast cancer von Mumin, Nuramalina H, Drobnitzky, Neele, Patel, Agata, Lourenco, Luiza Madia, Cahill, Fiona F, Jiang, Yanyan, Kong, Anthony, Ryan, Anderson J

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Cardio-Respiratory synchronized bSSFP MRI for high throughput in vivo lung tumour quantification von Gomes, Ana L, Kinchesh, Paul, Gilchrist, Stuart, Allen, Philip D, Lourenço, Luiza Madia, Ryan, Anderson J, Smart, Sean C

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Shock subtypes by left ventricular ejection fraction following out-of-hospital cardiac arrest von Anderson, Ryan J, Jinadasa, Sayuri P, Hsu, Leeyen, Ghafouri, Tiffany Bita, Tyagi, Sanjeev, Joshua, Jisha, Mueller, Ariel, Talmor, Daniel, Sell, Rebecca E, Beitler, Jeremy R

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Hypoxia Potentiates the Radiation-Sensitizing Effect of Olaparib in Human Non-Small Cell Lung Cancer Xenografts by Contextual Synthetic Lethality von Jiang, Yanyan, PhD, Verbiest, Tom, MSc, Devery, Aoife M., PhD, Bokobza, Sivan M., PhD, Weber, Anika M., PhD, Leszczynska, Katarzyna B., PhD, Hammond, Ester M., PhD, Ryan, Anderson J., PhD

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Diagnosis and Management of Pulmonary Hypertension in the Modern Era: Insights from the 6th World Symposium von Thomas, Christopher A., Anderson, Ryan J., Condon, David F., de Jesus Perez, Vinicio A.

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The cell-line-derived subcutaneous tumor model in preclinical cancer research von Stribbling, Stephen M., Ryan, Anderson J.

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Distinct Patterns of Cytokine and Angiogenic Factor Modulation and Markers of Benefit for Vandetanib and/or Chemotherapy in Patients With Non–Small-Cell Lung Cancer von HANRAHAN, Emer O, LIN, Heather Y, JOHNSON, Bruce E, HEYMACH, John V, KIM, Edward S, SHAOYU YAN, DU, Danny Z, MCKEE, Kathryn S, TRAN, Hai T, LEE, J. Jack, RYAN, Anderson J, LANGMUIR, Peter

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Baseline Vascular Endothelial Growth Factor Concentration as a Potential Predictive Marker of Benefit from Vandetanib in Non–Small Cell Lung Cancer von HANRAHAN, Emer O, RYAN, Anderson J, MANN, Helen, KENNEDY, Sarah J, LANGMUIR, Peter, NATALE, Ronald B, HERBST, Roy S, JOHNSON, Bruce E, HEYMACH, John V

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Beyond cancer cells: Targeting the tumor microenvironment with gene therapy and armed oncolytic virus von Wan, Peter Kok-Ting, Ryan, Anderson J., Seymour, Leonard W.

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Identification of anticancer drugs to radiosensitise BRAF -wild-type and mutant colorectal cancer von Carter, Rebecca, Cheraghchi-Bashi, Azadeh, Westhorpe, Adam, Yu, Sheng, Shanneik, Yasmin, Seraia, Elena, Ouaret, Djamila, Inoue, Yasuhiro, Koch, Catherine, Wilding, Jenny, Ebner, Daniel, Ryan, Anderson J, Buffa, Francesca M, Sharma, Ricky A

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Short-Course Treatment With Gefitinib Enhances Curative Potential of Radiation Therapy in a Mouse Model of Human Non-Small Cell Lung Cancer von Bokobza, Sivan M., PhD, Jiang, Yanyan, PhD, Weber, Anika M., MSc, Devery, Aoife M., PhD, Ryan, Anderson J., PhD

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Orthotopic and metastatic tumour models in preclinical cancer research von Stribbling, Stephen M., Beach, Callum, Ryan, Anderson J.

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The lifesaving effects of cardiac adhesions von Richardson, Adam L., Richardson, Olivia K., Guan, Rebecca L., Anderson, Ryan J., Van Meter, Tracy L.

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CONCORDE: A phase I platform study of novel agents in combination with conventional radiotherapy in non-small-cell lung cancer von Walls, Gerard M., Oughton, Jamie B., Chalmers, Anthony J., Brown, Sarah, Collinson, Fiona, Forster, Martin D., Franks, Kevin N., Gilbert, Alexandra, Hanna, Gerard G., Hannaway, Nicola, Harrow, Stephen, Haswell, Tom, Hiley, Crispin T., Hinsley, Samantha, Krebs, Matthew, Murden, Geraldine, Phillip, Rachel, Ryan, Anderson J., Salem, Ahmed, Sebag-Montefoire, David, Shaw, Paul, Twelves, Chris J., Walker, Katrina, Young, Robin J., Faivre-Finn, Corinne, Greystoke, Alastair

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The tyrosine kinase inhibitor ZD6474 blocks proliferation of RET mutant medullary thyroid carcinoma cells von Vitagliano, Donata, De Falco, Valentina, Tamburrino, Anna, Coluzzi, Sabrina, Troncone, Giancarlo, Chiappetta, Gennaro, Ciardiello, Fortunato, Tortora, Giampaolo, Fagin, James A, Ryan, Anderson J, Carlomagno, Francesca, Santoro, Massimo

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