Toxicity Testing in the 21st Century: Bringing the Vision to Life von Andersen, Melvin E., Krewski, Daniel

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Ultrasensitive response motifs: basic amplifiers in molecular signalling networks von Zhang, Qiang, Bhattacharya, Sudin, Andersen, Melvin E.

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Toxicity testing in the 21 century: defining new risk assessment approaches based on perturbation of intracellular toxicity pathways von Bhattacharya, Sudin, Zhang, Qiang, Carmichael, Paul L, Boekelheide, Kim, Andersen, Melvin E

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Hepatocyte-specific Nrf2 deficiency mitigates high-fat diet-induced hepatic steatosis: Involvement of reduced PPARγ expression von Li, Lu, Fu, Jingqi, Liu, Dan, Sun, Jing, Hou, Yongyong, Chen, Chengjie, Shao, Junbo, Wang, Linlin, Wang, Xin, Zhao, Rui, Wang, Huihui, Andersen, Melvin E., Zhang, Qiang, Xu, Yuanyuan, Pi, Jingbo

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Adipose Deficiency of Nrf2 in ob/ob Mice Results in Severe Metabolic Syndrome von PENG XUE, YONGYONG HOU, QIANG ZHANG, ANDERSEN, Melvin E, JINGBO PI, YANYAN CHEN, BEI YANG, JINGQI FU, HONGZHI ZHENG, YARBOROUGH, Kathy, WOODS, Courtney G, DIANXIN LIU, YAMAMOTO, Masayuki

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A deterministic map of Waddington's epigenetic landscape for cell fate specification von Bhattacharya, Sudin, Zhang, Qiang, Andersen, Melvin E

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Adaptive Posttranslational Control in Cellular Stress Response Pathways and Its Relationship to Toxicity Testing and Safety Assessment von Zhang, Qiang, Bhattacharya, Sudin, Pi, Jingbo, Clewell, Rebecca A, Carmichael, Paul L, Andersen, Melvin E

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Integration of Dosimetry, Exposure, and High-Throughput Screening Data in Chemical Toxicity Assessment von Wetmore, Barbara A., Wambaugh, John F., Ferguson, Stephen S., Sochaski, Mark A., Rotroff, Daniel M., Freeman, Kimberly, Clewell, Harvey J., Dix, David J., Andersen, Melvin E., Houck, Keith A., Allen, Brittany, Judson, Richard S., Singh, Reetu, Kavlock, Robert J., Richard, Ann M., Thomas, Russell S.

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Adipocyte-specific deficiency of Nfe2l1 disrupts plasticity of white adipose tissues and metabolic homeostasis in mice von Hou, Yongyong, Liu, Zhiyuan, Zuo, Zhuo, Gao, Tianchang, Fu, Jingqi, Wang, Huihui, Xu, Yuanyuan, Liu, Dianxin, Yamamoto, Masayuki, Zhu, Beibei, Zhang, Yiguo, Andersen, Melvin E., Zhang, Qiang, Pi, Jingbo

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Temporal concordance between apical and transcriptional points of departure for chemical risk assessment von Thomas, Russell S, Wesselkamper, Scott C, Wang, Nina Ching Y, Zhao, Q Jay, Petersen, Dan D, Lambert, Jason C, Cote, Ila, Yang, Longlong, Healy, Eric, Black, Michael B, Clewell, 3rd, Harvey J, Allen, Bruce C, Andersen, Melvin E

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Reactive Oxygen Species as a Signal in Glucose-Stimulated Insulin Secretion von JINGBO PI, YUSHI BAI, COLLINS, Sheila, QIANG ZHANG, WONG, Victoria, FLOERING, Lisa M, DANIEL, Kiefer, FLEECE, Jeffrey M, DEENEY, Jude T, ANDERSEN, Melvin E, CORKEY, Barbara E

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ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function von Pi, Jingbo, Zhang, Qiang, Fu, Jingqi, Woods, Courtney G., Hou, Yongyong, Corkey, Barbara E., Collins, Sheila, Andersen, Melvin E.

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Co-culture of Hepatocytes and Kupffer Cells as an In Vitro Model of Inflammation and Drug-Induced Hepatotoxicity von Rose, Kelly A., Holman, Natalie S., Green, Angela M., Andersen, Melvin E., LeCluyse, Edward L.

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Genetic variability in a frozen batch of MCF-7 cells invisible in routine authentication affecting cell function von Kleensang, Andre, Vantangoli, Marguerite M., Odwin-DaCosta, Shelly, Andersen, Melvin E., Boekelheide, Kim, Bouhifd, Mounir, Fornace, Albert J., Li, Heng-Hong, Livi, Carolina B., Madnick, Samantha, Maertens, Alexandra, Rosenberg, Michael, Yager, James D., Zhao, Liang, Hartung, Thomas

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Long isoforms of NRF1 negatively regulate adipogenesis via suppression of PPARγ expression von Xue, Peng, Hou, Yongyong, Zuo, Zhuo, Wang, Zhendi, Ren, Suping, Dong, Jian, Fu, Jingqi, Wang, Huihui, Andersen, Melvin E., Zhang, Qiang, Xu, Yuanyuan, Pi, Jingbo

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Low-Level Arsenic Impairs Glucose-Stimulated Insulin Secretion in Pancreatic Beta Cells: Involvement of Cellular Adaptive Response to Oxidative Stress von Fu, Jingqi, Woods, Courtney G., Yehuda-Shnaidman, Einav, Zhang, Qiang, Wong, Victoria, Collins, Sheila, Sun, Guifan, Andersen, Melvin E., Pi, Jingbo

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Perfluoroalkyl Acids and Related Chemistries—Toxicokinetics and Modes of Action von Andersen, Melvin E., Butenhoff, John L., Chang, Shu-Ching, Farrar, David G., Kennedy, Gerald L., Lau, Christopher, Olsen, Geary W., Seed, Jennifer, Wallace, Kendall B.

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Dose response relationship in anti-stress gene regulatory networks von Zhang, Qiang, Andersen, Melvin E

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Adverse Outcome Pathways can drive non-animal approaches for safety assessment von Burden, Natalie, Sewell, Fiona, Andersen, Melvin E., Boobis, Alan, Chipman, J. Kevin, Cronin, Mark T. D., Hutchinson, Thomas H., Kimber, Ian, Whelan, Maurice

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Iodoacetic Acid Activates Nrf2-Mediated Antioxidant Response in Vitro and in Vivo von Wang, Shu, Zheng, Weiwei, Liu, Xiaolin, Xue, Peng, Jiang, Songhui, Lu, Daru, Zhang, Qiang, He, Gensheng, Pi, Jingbo, Andersen, Melvin E, Tan, Hui, Qu, Weidong

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