Preclinical studies of RA475, a guanidine-substituted spirocyclic candidate RPN13/ADRM1 inhibitor for treatment of ovarian cancer von Anchoori, Ravi K, Tseng, Ssu-Hsueh, Tsai, Hua-Ling, Palande, Vikrant, Rudek, Michelle A, Roden, Richard B S

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Development and anticancer properties of Up284, a spirocyclic candidate ADRM1/RPN13 inhibitor von Anchoori, Ravi K, Anchoori, Vidyasagar, Lam, Brandon, Tseng, Ssu-Hsueh, Das, Samarjit, Velasquez, Fernanda Carrizo, Karanam, Balasubramanyam, Poddatoori, Deepika, Patnam, Ramesh, Rudek, Michelle A, Chang, Yung-Nien, Roden, Richard B S

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Chirality and asymmetry increase the potency of candidate ADRM1/RPN13 inhibitors von Anchoori, Ravi K, George, Logan, Tseng, Ssu-Hsueh, Lam, Brandon, Polkampally, Srinidhi, Amiano, Anjali D, Foran, Palmer, Tsingine, Hannah, Samanapally, Harideep, Carrizo Velasquez, Fernanda, Das, Samarjit, Xing, Deyin, Bin Salam, Ahmad, Karanam, Balasubramanyam, Hung, Chien-Fu, Roden, Richard B S

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The Proteasome Ubiquitin Receptor hRpn13 and Its Interacting Deubiquitinating Enzyme Uch37 Are Required for Proper Cell Cycle Progression von Randles, Leah, Anchoori, Ravi K., Roden, Richard B.S., Walters, Kylie J.

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Structure-function analyses of candidate small molecule RPN13 inhibitors with antitumor properties von Anchoori, Ravi K, Tan, Marietta, Tseng, Ssu-Hsueh, Peng, Shiwen, Soong, Ruey-Shyang, Algethami, Aliyah, Foran, Palmer, Das, Samarjit, Wang, Chenguang, Wang, Tian-Li, Liang, Hong, Hung, Chien-Fu, Roden, Richard B S

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mTORC1 feedback to AKT modulates lysosomal biogenesis through MiT/TFE regulation von Asrani, Kaushal, Murali, Sanjana, Lam, Brandon, Na, Chan-Hyun, Phatak, Pornima, Sood, Akshay, Kaur, Harsimar, Khan, Zoya, Noë, Michaël, Anchoori, Ravi K, Talbot, Jr, C Conover, Smith, Barbara, Skaro, Michael, Lotan, Tamara L

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Bis-benzylidine Piperidone RA190 treatment of hepatocellular carcinoma via binding RPN13 and inhibiting NF-κB signaling von Soong, Ruey-Shyang, Anchoori, Ravi K, Roden, Richard B S, Cho, Rou-Ling, Chen, Yi-Chan, Tseng, Sheng-Chieh, Huang, Yun-Li, Liao, Po-Cheng, Shyu, Yu-Chiau

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Stressing the ubiquitin-proteasome system without 20S proteolytic inhibition selectively kills cervical cancer cells von Anchoori, Ravi K, Khan, Saeed R, Sueblinvong, Thanasak, Felthauser, Alicia, Iizuka, Yoshie, Gavioli, Riccardo, Destro, Federica, Isaksson Vogel, Rachel, Peng, Shiwen, Roden, Richard B S, Bazzaro, Martina

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Small-Molecule RA-9 Inhibits Proteasome-Associated DUBs and Ovarian Cancer In Vitro and In Vivo via Exacerbating Unfolded Protein Responses von COUGHLIN, Kathleen, ANCHOORI, Ravi, LIZUKA, Yoshie, MEINTS, Joyce, MACNEILL, Lauren, VOGEL, Rachel Isaksson, ORLOWSKI, Robert Z, LEE, Michael K, RODEN, Richard B. S, BAZZARO, Martina

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A bis-Benzylidine Piperidone Targeting Proteasome Ubiquitin Receptor RPN13/ADRM1 as a Therapy for Cancer von Anchoori, Ravi K., Karanam, Balasubramanyam, Peng, Shiwen, Wang, Joshua W., Jiang, Rosie, Tanno, Toshihiko, Orlowski, Robert Z., Matsui, William, Zhao, Ming, Rudek, Michelle A., Hung, Chien-fu, Chen, Xiang, Walters, Kylie J., Roden, Richard B.S.

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α,β-Unsaturated Carbonyl System of Chalcone-Based Derivatives Is Responsible for Broad Inhibition of Proteasomal Activity and Preferential Killing of Human Papilloma Virus (HPV) Po... von Bazzaro, Martina, Anchoori, Ravi K, Mudiam, Mohana Krishna R, Issaenko, Olga, Kumar, Srinivas, Karanam, Balasubramanyam, Lin, Zhenhua, Isaksson Vogel, Rachel, Gavioli, Riccardo, Destro, Federica, Ferretti, Valeria, Roden, Richard B. S, Khan, Saeed R

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Simultaneous inhibition of deubiquitinating enzymes (DUBs) and autophagy synergistically kills breast cancer cells von Vogel, Rachel Isaksson, Coughlin, Kathleen, Scotti, Alessandra, Iizuka, Yoshie, Anchoori, Ravi, Roden, Richard B S, Marastoni, Mauro, Bazzaro, Martina

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Covalent Rpn13-Binding Inhibitors for the Treatment of Ovarian Cancer von Anchoori, Ravi K, Jiang, Rosie, Peng, Shiwen, Soong, Ruey-shyang, Algethami, Aliyah, Rudek, Michelle A, Anders, Nicole, Hung, Chien-Fu, Chen, Xiang, Lu, Xiuxiu, Kayode, Olumide, Dyba, Marzena, Walters, Kylie J, Roden, Richard B. S

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ADRM1-amplified metastasis gene in gastric cancer von Fejzo, Marlena S., Anderson, Lee, Chen, Hsiao-Wang, Anghel, Adrian, Zhuo, Jiaying, Anchoori, Ravi, Roden, Richard, Slamon, Dennis J.

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Early and consistent overexpression of ADRM1 in ovarian high-grade serous carcinoma von Jiang, Rosie T, Yemelyanova, Anna, Xing, Deyin, Anchoori, Ravi K, Hamazaki, Jun, Murata, Shigeo, Seidman, Jeffrey D, Wang, Tian-Li, Roden, Richard B S

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Potent genistein derivatives as inhibitors of estrogen receptor alpha-positive breast cancer von Marik, Radharani, Allu, Madhan, Anchoori, Ravi, Stearns, Vered, Umbricht, Christopher B., Khan, Saeed

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Targeted inhibition of hedgehog signaling by cyclopamine prodrugs for advanced prostate cancer von Kumar, Srinivas K., Roy, Indrajit, Anchoori, Ravi K., Fazli, Sarah, Maitra, Anirban, Beachy, Philip A., Khan, Saeed R.

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RPN13/ADRM1 inhibitor reverses immunosuppression by myeloid-derived suppressor cells von Soong, Ruey-Shyang, Anchoori, Ravi K, Yang, Benjamin, Yang, Andrew, Tseng, Ssu-Hsueh, He, Liangmei, Tsai, Ya-Chea, Roden, Richard B S, Hung, Chien-Fu

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RPN13/ADRM1 inhibitor reverses immunosuppression by myeloid-derived suppressor cells von Soong, Ruey-Shyang, Anchoori, Ravi K., Yang, Benjamin, Yang, Andrew, Tseng, Ssu-Hsueh, He, Liangmei, Tsai, Ya-Chea, Roden, Richard B.S., Hung, Chien-Fu

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Fenugreek: A naturally occurring edible spice as an anticancer agent von Shabbeer, Shabana, Sobolewski, Michelle, Anchoori, Ravi Kumar, Kachhap, Sushant, Hidalgo, Manuel, Jimeno, Antonio, Davidson, Nancy E, Carducci, Michael, Khan, Saeed R

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