Enasidenib induces acute myeloid leukemia cell differentiation to promote clinical response von Amatangelo, Michael D., Quek, Lynn, Shih, Alan, Stein, Eytan M., Roshal, Mikhail, David, Muriel D., Marteyn, Benoit, Farnoud, Noushin Rahnamay, de Botton, Stephane, Bernard, Olivier A., Wu, Bin, Yen, Katharine E., Tallman, Martin S., Papaemmanuil, Elli, Penard-Lacronique, Virginie, Thakurta, Anjan, Vyas, Paresh, Levine, Ross L.

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Three-dimensional culture sensitizes epithelial ovarian cancer cells to EZH2 methyltransferase inhibition von Amatangelo, Michael, Garipov, Azat, Li, Hua, Conejo-Garcia, Jose R., Speicher, David, Zhang, Rugang

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Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers von Bitler, Benjamin G, Aird, Katherine M, Garipov, Azat, Li, Hua, Amatangelo, Michael, Kossenkov, Andrew V, Schultz, David C, Liu, Qin, Shih, Ie-Ming, Conejo-Garcia, Jose R, Speicher, David W, Zhang, Rugang

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Developing next generation immunomodulatory drugs and their combinations in multiple myeloma von Thakurta, Anjan, Pierceall, William E., Amatangelo, Michael D., Flynt, Erin, Agarwal, Amit

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Preparation of Extracellular Matrices Produced by Cultured and Primary Fibroblasts von Franco‐Barraza, Janusz, Beacham, Dorothy A., Amatangelo, Michael D., Cukierman, Edna

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Immunomodulation in Pomalidomide, Dexamethasone, and Daratumumab-Treated Patients with Relapsed/Refractory Multiple Myeloma von Pierceall, William E, Amatangelo, Michael D, Bahlis, Nizar J, Siegel, David S, Rahman, Adeeb, Van Oekelen, Oliver, Neri, Paola, Young, Mary, Chung, Weiyuan, Serbina, Natalya, Parekh, Samir, Agarwal, Amit, Thakurta, Anjan

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c-Myc expression and MEK1-induced Erk2 nuclear localization are required for TGF-beta induced epithelial―mesenchymal transition and invasion in prostate cancer von AMATANGELO, Michael D, GOODYEAR, Shaun, VARMA, Devika, STEARNS, Mark E

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Stroma-Derived Three-Dimensional Matrices Are Necessary and Sufficient to Promote Desmoplastic Differentiation of Normal Fibroblasts von Amatangelo, Michael D., Bassi, Daniel E., Klein-Szanto, Andrés J.P., Cukierman, Edna

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Combination Therapy with Epigallocatechin-3-Gallate and Doxorubicin in Human Prostate Tumor Modeling Studies: Inhibition of Metastatic Tumor Growth in Severe Combined Immunodeficie... von STEARNS, Mark E, AMATANGELO, Michael D, VARMA, Devika, SELL, Chris, GOODYEAR, Shaun M

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Role of ribosomal protein RPS2 in controlling let-7a expression in human prostate cancer von Wang, Min, Hu, Youji, Amatangelo, Michael D, Stearns, Mark E

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P868: MEZIGDOMIDE (MEZI) PLUS DEXAMETHASONE (DEX) IN PATIENTS (PTS) WITH RELAPSED/REFRACTORY MULTIPLE MYELOMA (RRMM): RESULTS FROM THE DOSE‐EXPANSION PHASE OF THE CC‐92480‐MM‐001 T... von Bahlis, Nizar J, Trudel, Suzanne, Quach, Hang, Popat, Rakesh, Lonial, Sagar, Orlowski, Robert Z, Kim, Kihyun, Mateos, Maria‐Victoria, Pawlyn, Charlotte, Ramasamy, Karthik, Martinez‐Lopez, Joaquín, Casas‐Avilés, Ignacio, Spirli, Alessia, Gong, Jing, Amatangelo, Michael, Katz, Jessica, Maciag, Paulo, Peluso, Teresa, Richardson, Paul

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Preparation of Extracellular Matrices Produced by Cultured and Primary Fibroblasts von Beacham, Dorothy A., Amatangelo, Michael D., Cukierman, Edna

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Iberdomide (CC-220) is a potent cereblon E3 ligase modulator with antitumor and immunostimulatory activities in lenalidomide- and pomalidomide-resistant multiple myeloma cells with... von Bjorklund, Chad C., Kang, Jian, Amatangelo, Michael, Polonskaia, Ann, Katz, Mark, Chiu, Hsiling, Couto, Suzana, Wang, Maria, Ren, Yan, Ortiz, Maria, Towfic, Fadi, Flynt, J. Erin, Pierceall, William, Thakurta, Anjan

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Mezigdomide plus Dexamethasone in Relapsed and Refractory Multiple Myeloma von Richardson, Paul G., Trudel, Suzanne, Popat, Rakesh, Mateos, María-Victoria, Vangsted, Annette J., Ramasamy, Karthik, Martinez-Lopez, Joaquín, Quach, Hang, Orlowski, Robert Z., Arnao, Mario, Lonial, Sagar, Karanes, Chatchada, Pawlyn, Charlotte, Kim, Kihyun, Oriol, Albert, Berdeja, Jesus G., Rodríguez Otero, Paula, Casas-Avilés, Ignacio, Spirli, Alessia, Poon, Jennifer, Li, Shaoyi, Gong, Jing, Wong, Lilly, Lamba, Manisha, Pierce, Daniel W., Amatangelo, Michael, Peluso, Teresa, Maciag, Paulo, Katz, Jessica, Pourdehnad, Michael, Bahlis, Nizar J.

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Combination Therapy with Epigallocatechin-3-Gallate and Doxorubicin in Human Prostate Tumor Modeling Studies von Stearns, Mark E, Amatangelo, Michael D, Varma, Devika, Sell, Chris, Goodyear, Shaun M

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Clonal heterogeneity of acute myeloid leukemia treated with the IDH2 inhibitor enasidenib von Quek, Lynn, David, Muriel D., Kennedy, Alison, Metzner, Marlen, Amatangelo, Michael, Shih, Alan, Stoilova, Bilyana, Quivoron, Cyril, Heiblig, Maël, Willekens, Christophe, Saada, Véronique, Alsafadi, Samar, Vijayabaskar, M. S., Peniket, Andy, Bernard, Oliver A., Agresta, Sam, Yen, Katharine, MacBeth, Kyle, Stein, Eytan, Vassiliou, George S., Levine, Ross, De Botton, Stephane, Thakurta, Anjan, Penard-Lacronique, Virginie, Vyas, Paresh

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RRMM and Post-BCMA Treated Subjects from the CC-220-MM-001 Study Show Increased Genomic Aberrations Associated with High-Risk and Significant Dysfunction in CD4+ T-Cell Compartment... von Amatangelo, Michael, Flynt, Erin, Stong, Nicholas, Ortiz, Maria, Ray, Pradipta, Wang, Maria, van de Donk, Niels W.C.J., Lonial, Sagar, Raval, Aparna, Gandhi, Anita K.

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Iberdomide Enhances Dara Mediated Cytotoxicity through Upregulation of CDC Activity and Elevated NK Cell Mediated ADCC von Ma, Peilin, Sridharan, Vinidhra, Wollerman, Krista, Dutta, Debjani, Singh, Ram Kumar, Mukherjee, Sambuddo, Bjorklund, Chad C., Hagner, Patrick R, Amatangelo, Michael, Gandhi, Anita K.

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CC-92480 Enhances Cell-Autonomous Cytotoxicity through Blockade of G 2/M Transition When Combined with Bortezomib/Dexamethasone in Pre-Clinical Multiple Myeloma von Bjorklund, Chad C, Amatangelo, Michael, Kang, Jian, Chiu, Hsiling, Mukhopadhyay, Archana, Wollerman, Krista, Pourdehnad, Michael, Hagner, Patrick, Thakurta, Anjan

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P-335 Iberdomide Is Immune Stimulatory and Induces Deep Anti-Myeloma Activity Across Doses in Combination With Daratumumab in Patients With TNE NDMM From the CC-220-MM-001 Study von Amatangelo, Michael, Wang, Maria, Maciag, Paulo, Balari, Anna Sureda, van de Donk, Niels, Lonial, Sagar, Gandhi, Anita K., Martin, Nathan

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