Design of an in vitro biocatalytic cascade for the manufacture of islatravir von Huffman, Mark A, Fryszkowska, Anna, Alvizo, Oscar, Borra-Garske, Margie, Campos, Kevin R, Canada, Keith A, Devine, Paul N, Duan, Da, Forstater, Jacob H, Grosser, Shane T, Halsey, Holst M, Hughes, Gregory J, Jo, Junyong, Joyce, Leo A, Kolev, Joshua N, Liang, Jack, Maloney, Kevin M, Mann, Benjamin F, Marshall, Nicholas M, McLaughlin, Mark, Moore, Jeffrey C, Murphy, Grant S, Nawrat, Christopher C, Nazor, Jovana, Novick, Scott, Patel, Niki R, Rodriguez-Granillo, Agustina, Robaire, Sandra A, Sherer, Edward C, Truppo, Matthew D, Whittaker, Aaron M, Verma, Deeptak, Xiao, Li, Xu, Yingju, Yang, Hao

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Directed evolution of an ultrastable carbonic anhydrase for highly efficient carbon capture from flue gas von Alvizo, Oscar, Nguyen, Luan J., Savile, Christopher K., Bresson, Jamie A., Lakhapatri, Satish L., Solis, Earl O. P., Fox, Richard J., Broering, James M., Benoit, Michael R., Zimmerman, Sabrina A., Novick, Scott J., Liang, Jack, Lalonde, James J.

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Chemoenzymatic conversion of amides to enantioenriched alcohols in aqueous medium von Dander, Jacob E., Giroud, Maude, Racine, Sophie, Darzi, Evan R., Alvizo, Oscar, Entwistle, David, Garg, Neil K.

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Evaluating and optimizing computational protein design force fields using fixed composition-based negative design von Alvizo, Oscar, Mayo, Stephen L

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Computational protein design promises to revolutionize protein engineering von Alvizo, Oscar, Allen, Benjamin D, Mayo, Stephen L

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Engineering an Amine Transaminase for the Efficient Production of a Chiral Sacubitril Precursor von Novick, Scott J, Dellas, Nikki, Garcia, Ravi, Ching, Charlene, Bautista, Abigail, Homan, David, Alvizo, Oscar, Entwistle, David, Kleinbeck, Florian, Schlama, Thierry, Ruch, Thomas

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A kinase-cGAS cascade to synthesize a therapeutic STING activator von McIntosh, John A., Liu, Zhijian, Andresen, Brian M., Marzijarani, Nastaran Salehi, Moore, Jeffrey C., Marshall, Nicholas M., Borra-Garske, Margie, Obligacion, Jennifer V., Fier, Patrick S., Peng, Feng, Forstater, Jacob H., Winston, Matthew S., An, Chihui, Chang, Wonsuk, Lim, Jongwon, Huffman, Mark A., Miller, Steven P., Tsay, Fuh-Rong, Altman, Michael D., Lesburg, Charles A., Steinhuebel, Dietrich, Trotter, B. Wesley, Cumming, Jared N., Northrup, Alan, Bu, Xiaodong, Mann, Benjamin F., Biba, Mirlinda, Hiraga, Kaori, Murphy, Grant S., Kolev, Joshua N., Makarewicz, Amanda, Pan, Weilan, Farasat, Iman, Bade, Rachel S., Stone, Kevin, Duan, Da, Alvizo, Oscar, Adpressa, Donovan, Guetschow, Erik, Hoyt, Erik, Regalado, Erik L., Castro, Steve, Rivera, Nelo, Smith, Joseph P., Wang, Fengqiang, Crespo, Alejandro, Verma, Deeptak, Axnanda, Stephanus, Dance, Zachary E. X., Devine, Paul N., Tschaen, David, Canada, Keith A., Bulger, Paul G., Sherry, Benjamin D., Truppo, Matthew D., Ruck, Rebecca T., Campeau, Louis-Charles, Bennett, David Jonathan, Humphrey, Guy R., Campos, Kevin R., Maddess, Matthew L.

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BioLindlar Catalyst: Ene‐Reductase‐Promoted Selective Bioreduction of Cyanoalkynes to Give (Z)‐Cyanoalkenes von González‐Rodríguez, Jorge, González‐Granda, Sergio, Kumar, Hirdesh, Alvizo, Oscar, Escot, Lorena, Hailes, Helen C., Gotor‐Fernández, Vicente, Lavandera, Iván

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An engineered T7 RNA polymerase for efficient co-transcriptional capping with reduced dsRNA byproducts in mRNA synthesis von Miller, Mathew, Alvizo, Oscar, Baskerville, Scott, Chintala, Avinash, Chng, Chinping, Dassie, Justin, Dorigatti, Jonathan, Huisman, Gjalt, Jenne, Stephan, Kadam, Supriya, Leatherbury, Neil, Lutz, Stefan, Mayo, Melissa, Mukherjee, Arpan, Sero, Antoinette, Sundseth, Stuart, Penfield, Jonathan, Riggins, James, Zhang, Xiyun

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Enhancing the Imine Reductase Activity of a Promiscuous Glucose Dehydrogenase for Scalable Manufacturing of a Chiral Neprilysin Inhibitor Precursor von Yi, Xiang, Kleinbeck, Florian, Ching, Charlene, Boghospor, Lorita, Gomes, Sandy, Alvizo, Oscar, Allmendinger, Thomas, Fell, Jason, Subramanian, Nandhitha, Li, Michelle, Garcia, Ravi, Riggins, James, Entwistle, David, Richter, Yvonne, Gschwend, Daniel, Lauener, Liam, Peat, Thomas S., Lebhar, Hélène, Schlama, Thierry, Ruch, Thomas

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Development of a Biocatalytic Aerobic Oxidation for the Manufacturing Route to Islatravir von Shaw, Megan H., Fryszkowska, Anna, Alvizo, Oscar, Attadgie, Ilana, Borra-Garske, Margie, Devine, Paul N., Duan, Da, Grosser, Shane T., Forstater, Jacob H., Hughes, Gregory J., Maloney, Kevin M., Margelefsky, Eric L., Mattern, Keith A., Miller, Margaret T., Nawrat, Christopher C., Nazor, Jovana, Orth, Peter, Ouimet, Claire M., Robaire, Sandra A., Ruccolo, Serge, Schwalm, Erica L., Verma, Deeptak, Xiao, Li, Zhang, Victoria

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Synthesis of Vibegron Enabled by a Ketoreductase Rationally Designed for High pH Dynamic Kinetic Reduction von Xu, Feng, Kosjek, Birgit, Cabirol, Fabien L., Chen, Haibin, Desmond, Richard, Park, Jeonghan, Gohel, Anupam P., Collier, Steven J., Smith, Derek J., Liu, Zhuqing, Janey, Jacob M., Chung, John Y. L., Alvizo, Oscar

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A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins von Fryszkowska, Anna, An, Chihui, Alvizo, Oscar, Banerjee, Goutami, Canada, Keith A., Cao, Yang, DeMong, Duane, Devine, Paul N., Duan, Da, Elgart, David M., Farasat, Iman, Gauthier, Donald R., Guidry, Erin N., Jia, Xiujuan, Kong, Jongrock, Kruse, Nikki, Lexa, Katrina W., Makarov, Alexey A., Mann, Benjamin F., Milczek, Erika M., Mitchell, Vesna, Nazor, Jovana, Neri, Claudia, Orr, Robert K., Orth, Peter, Phillips, Eric M., Riggins, James N., Schafer, Wes A., Silverman, Steven M., Strulson, Christopher A., Subramanian, Nandhitha, Voladri, Rama, Yang, Hao, Yang, Jie, Yi, Xiang, Zhang, Xiyun, Zhong, Wendy

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Synthesis of the GPR40 Partial Agonist MK-8666 through a Kinetically Controlled Dynamic Enzymatic Ketone Reduction von Hyde, Alan M, Liu, Zhijian, Kosjek, Birgit, Tan, Lushi, Klapars, Artis, Ashley, Eric R, Zhong, Yong-Li, Alvizo, Oscar, Agard, Nicholas J, Liu, Guiquan, Gu, Xiuyan, Yasuda, Nobuyoshi, Limanto, John, Huffman, Mark A, Tschaen, David M

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BioLindlar Catalyst: Ene‐Reductase‐Promoted Selective Bioreduction of Cyanoalkynes to Give (Z)‐Cyanoalkenes von González‐Rodríguez, Jorge, González‐Granda, Sergio, Kumar, Hirdesh, Alvizo, Oscar, Escot, Lorena, Hailes, Helen C., Gotor‐Fernández, Vicente, Lavandera, Iván

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Structural, kinetic, and thermodynamic studies of specificity designed HIV‐1 protease von Alvizo, Oscar, Mittal, Seema, Mayo, Stephen L., Schiffer, Celia A.

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Synthesis of Vibegron Enabled by a Ketoreductase Rationally Designed for High pH Dynamic Kinetic Reduction von Xu, Feng, Kosjek, Birgit, Cabirol, Fabien L., Chen, Haibin, Desmond, Richard, Park, Jeonghan, Gohel, Anupam P., Collier, Steven J., Smith, Derek J., Liu, Zhuqing, Janey, Jacob M., Chung, John Y. L., Alvizo, Oscar

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CHEMICALLY MODIFIED CARBONIC ANHYDRASES USEFUL IN CARBON CAPTURE SYSTEMS von NOVICK, SCOTT, ALVIZO, OSCAR

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ENGINEERED THREONINE ALDOLASES AND AMINO ACID DECARBOXYLASES von ALVIZO, Oscar, SUBRAMANIAN, Nandhitha, SCHLAMA, Thierry, NOVICK, Scott, J

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ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION OF KETONE AND AMINE COMPOUNDS von Alvizo, Oscar, Mayo, Melissa Ann, Moore, Jeffrey C

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