Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mou... von Meilandt, William J, Ngu, Hai, Gogineni, Alvin, Lalehzadeh, Guita, Lee, Seung-Hye, Srinivasan, Karpagam, Imperio, Jose, Wu, Tiffany, Weber, Martin, Kruse, Agatha J, Stark, Kimberly L, Chan, Pamela, Kwong, Mandy, Modrusan, Zora, Friedman, Brad A, Elstrott, Justin, Foreman, Oded, Easton, Amy, Sheng, Morgan, Hansen, David V

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Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy von Wu, Tiffany, Dejanovic, Borislav, Gandham, Vineela D., Gogineni, Alvin, Edmonds, Rose, Schauer, Stephen, Srinivasan, Karpagam, Huntley, Melanie A., Wang, Yuanyuan, Wang, Tzu-Ming, Hedehus, Maj, Barck, Kai H., Stark, Maya, Ngu, Hai, Foreman, Oded, Meilandt, William J., Elstrott, Justin, Chang, Michael C., Hansen, David V., Carano, Richard A.D., Sheng, Morgan, Hanson, Jesse E.

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The CLEC-2–podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture von Astarita, Jillian L, Cremasco, Viviana, Fu, Jianxin, Darnell, Max C, Peck, James R, Nieves-Bonilla, Janice M, Song, Kai, Kondo, Yuji, Woodruff, Matthew C, Gogineni, Alvin, Onder, Lucas, Ludewig, Burkhard, Weimer, Robby M, Carroll, Michael C, Mooney, David J, Xia, Lijun, Turley, Shannon J

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Combined PD-L1/TGFβ blockade allows expansion and differentiation of stem cell-like CD8 T cells in immune excluded tumors von Castiglioni, Alessandra, Yang, Yagai, Williams, Katherine, Gogineni, Alvin, Lane, Ryan S., Wang, Amber W., Shyer, Justin A., Zhang, Zhe, Mittman, Stephanie, Gutierrez, Alan, Astarita, Jillian L., Thai, Minh, Hung, Jeffrey, Yang, Yeqing Angela, Pourmohamad, Tony, Himmels, Patricia, De Simone, Marco, Elstrott, Justin, Capietto, Aude-Hélène, Cubas, Rafael, Modrusan, Zora, Sandoval, Wendy, Ziai, James, Gould, Stephen E., Fu, Wenxian, Wang, Yulei, Koerber, James T., Sanjabi, Shomyseh, Mellman, Ira, Turley, Shannon J., Müller, Sören

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Enhancing the antitumor efficacy of a cell-surface death ligand by covalent membrane display von Nair, Pradeep M., Flores, Heather, Gogineni, Alvin, Marsters, Scot, Lawrence, David A., Kelley, Robert F., Ngu, Hai, Sagolla, Meredith, Komuves, Laszlo, Bourgon, Richard, Settleman, Jeffrey, Ashkenazi, Avi

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Inhibition of VEGF-C modulates distal lymphatic remodeling and secondary metastasis von Gogineni, Alvin, Caunt, Maresa, Crow, Ailey, Lee, Chingwei V, Fuh, Germaine, van Bruggen, Nicholas, Ye, Weilan, Weimer, Robby M

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Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration von Pozniak, Christine D, Sengupta Ghosh, Arundhati, Gogineni, Alvin, Hanson, Jesse E, Lee, Seung-Hye, Larson, Jessica L, Solanoy, Hilda, Bustos, Daisy, Li, Hong, Ngu, Hai, Jubb, Adrian M, Ayalon, Gai, Wu, Jiansheng, Scearce-Levie, Kimberly, Zhou, Qiang, Weimer, Robby M, Kirkpatrick, Donald S, Lewcock, Joseph W

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Proapoptotic Activation of Death Receptor 5 on Tumor Endothelial Cells Disrupts the Vasculature and Reduces Tumor Growth von Wilson, Nicholas S., Yang, Annie, Yang, Becky, Couto, Suzana, Stern, Howard, Gogineni, Alvin, Pitti, Robert, Marsters, Scot, Weimer, Robby M., Singh, Mallika, Ashkenazi, Avi

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486 Combined PD-L1/TGFβ blockade allows expansion and differentiation of stem cell-like CD8 T cells in immune excluded tumors von Williams, Katherine, Castiglioni, Alessandra, Yang, Yagai, Gogineni, Alvin, Astarita, Jillian, Elstrott, Justin, Modrusan, Zora, Mellman, Ira, Turley, Shannon, Muller, Soren

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Oncogenic BRAF is required for tumor growth and maintenance in melanoma models von HOEFLICH, Klaus P, GRAY, Daniel C, MURRAY, Lesley J, DAVIS, David P, SESHAGIRI, Somasekar, EBY, Michael T, TIEN, Janet Y, LEO WONG, BOWER, Janeko, GOGINENI, Alvin, JIPING ZHA, COLE, Mary J, STERN, Howard M

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Influences of Aortic Motion and Curvature on Vessel Expansion in Murine Experimental Aneurysms von Goergen, Craig J, Azuma, Junya, Barr, Kyla N, Magdefessel, Lars, Kallop, Dara Y, Gogineni, Alvin, Grewall, Amarjeet, Weimer, Robby M, Connolly, Andrew J, Dalman, Ronald L, Taylor, Charles A, Tsao, Philip S, Greve, Joan M

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Antibody-drug conjugates targeted to CD79 for the treatment of non-Hodgkin lymphoma von Polson, Andrew G., Yu, Shang-Fan, Elkins, Kristi, Zheng, Bing, Clark, Suzanna, Ingle, Gladys S., Slaga, Dionysos S., Giere, Lynne, Du, Changchun, Tan, Christine, Hongo, Jo-Anne, Gogineni, Alvin, Cole, Mary J., Vandlen, Richard, Stephan, Jean-Philippe, Young, Judy, Chang, Wesley, Scales, Suzie J., Ross, Sarajane, Eaton, Dan, Ebens, Allen

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Pegylated kunitz domain inhibitor suppresses hepsin-mediated invasive tumor growth and metastasis von Li, Wei, Wang, Bu-Er, Moran, Paul, Lipari, Terry, Ganesan, Rajkumar, Corpuz, Racquel, Ludlam, Mary J C, Gogineni, Alvin, Koeppen, Hartmut, Bunting, Stuart, Gao, Wei-Qiang, Kirchhofer, Daniel

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Neutrophil serine protease 4 is required for mast cell-dependent vascular leakage von AhYoung, Andrew P., Eckard, Sterling C., Gogineni, Alvin, Xi, Hongkang, Lin, S. Jack, Gerhardy, Stefan, Cox, Christian, Phung, Qui T., Hackney, Jason A., Katakam, Anand Kumar, Reichelt, Mike, Caplazi, Patrick, Manzanillo, Paolo, Zhang, Juan, Roose-Girma, Merone, Tam, Lucinda W., Newman, Robert J., Murthy, Aditya, Weimer, Robby M., Lill, Jennie R., Lee, Wyne P., Grimbaldeston, Michele, Kirchhofer, Daniel, van Lookeren Campagne, Menno

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An effector-reduced anti-β-amyloid (Aβ) antibody with unique aβ binding properties promotes neuroprotection and glial engulfment of Aβ von Adolfsson, Oskar, Pihlgren, Maria, Toni, Nicolas, Varisco, Yvan, Buccarello, Anna Lucia, Antoniello, Katia, Lohmann, Sophie, Piorkowska, Kasia, Gafner, Valerie, Atwal, Jasvinder K, Maloney, Janice, Chen, Mark, Gogineni, Alvin, Weimer, Robby M, Mortensen, Deborah L, Friesenhahn, Michel, Ho, Carole, Paul, Robert, Pfeifer, Andrea, Muhs, Andreas, Watts, Ryan J

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pHUSH: a single vector system for conditional gene expression von Gray, Daniel C, Hoeflich, Klaus P, Peng, Li, Gu, Zhenyu, Gogineni, Alvin, Murray, Lesley J, Eby, Mike, Kljavin, Noelyn, Seshagiri, Somasekar, Cole, Mary J, Davis, David P

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Disruption of IRE1α through its kinase domain attenuates multiple myeloma von Harnoss, Jonathan M., Le Thomas, Adrien, Shemorry, Anna, Marsters, Scot A., Lawrence, David A., Lu, Min, Chen, Yung-Chia Ariel, Qing, Jing, Totpal, Klara, Kan, David, Segal, Ehud, Merchant, Mark, Reichelt, Mike, Wallweber, Heidi Ackerly, Wang, Weiru, Clark, Kevin, Kaufman, Susan, Beresini, Maureen H., Laing, Steven T., Sandoval, Wendy, Lorenzo, Maria, Wu, Jiansheng, Ly, Justin, De Bruyn, Tom, Heidersbach, Amy, Haley, Benjamin, Gogineni, Alvin, Weimer, Robby M., Lee, Dong, Braun, Marie-Gabrielle, Rudolph, Joachim, VanWyngarden, Michael J., Sherbenou, Daniel W., Gomez-Bougie, Patricia, Amiot, Martine, Acosta-Alvear, Diego, Walter, Peter, Ashkenazi, Avi

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415 – Combined Blockade of Α4Β7 and ΑEΒ7 Integrins Leads to a Greater Reduction of Gut T Lymphocytes Over Either Pathway Alone von Dai, Bingbing, Ichikawa, Ryan, Keir, Mary, Yi, Tangsheng, Elstrott, Justin, Gogineni, Alvin

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Combined blockade of α4β7 and αEβ7 integrins leads to a greater reduction of gut proinflammatory T lymphocytes over either pathway alone von Dai, Bingbing, Hackney, Jason, Ichikawa, Ryan, Elstrott, Justin, Sun, Kai-Hui, Modrusan, Zora, Gogineni, Alvin, McBride, Jacqueline, Keir, Mary E, Yi, Tangsheng

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Reduced aversion to oral capsaicin following neurotoxic destruction of superficial medullary neurons expressing NK-1 receptors von Simons, Christopher T, Gogineni, Alvin G, Iodi Carstens, Mirela, Carstens, E

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