Genome-wide Analyses Identify KIF5A as a Novel ALS Gene von Kenna, Kevin P., Chia, Ruth, Dominov, Janice A., Nalls, Mike A., van Vugt, Joke J.F.A., Simone, Isabella, Caredda, Carla, Milia, Antonio, Floris, Gianluca, Caponnetto, Claudia, Mandich, Paola, Mora, Gabriele, Sideri, Riccardo, Penco, Silvana, Mandrioli, Jessica, Trojsi, Francesca, Ticca, Anna, Ortu, Enzo, Pugliatti, Maura, Benigni, Michele, Brunetti, Maura, Marrali, Giuseppe, Riva, Nilo, Conforti, Francesca L., Messina, Sonia, D’Alfonso, Sandra, Baloh, Robert H., Penny, Michelle, Moreno, Cristiane de Araujo Martins, Chung, Wendy K., Cirulli, Elizabeth T., Harris, Tim, Krueger, Brian J., Lasseigne, Brittany N., McKenna-Yasek, Diane, Myers, Richard M., Pulst, Stefan M., Raphael, Alya R., Rouleau, Guy A., Sapp, Peter C., Waite, Lindsay L., Wang, Quanli, Ostrow, Lyle W., Baas, Frank, Zaitlen, Noah, Hornstein, Eran, Patsopoulos, Nikolaos A., Kaye, Julia, Wyman, Stacia, LeNail, Alexander, Baxi, Emily, LeNail, Alex, Benatar, Michael, Hussain, Sumaira, Swenson, Andrea, Jackson, Carlayne, So, Yuen, Wuu, Joanne, Silani, Vincenzo, Fogh, Isabella, Cereda, Cristina, Ceroni, Mauro, Mazzini, Letizia, Maderna, Luca, Sorarù, Gianni, Bernard, Emilien, Laaksovirta, Hannu, McKenna-Yasek, Diane, Asress, Seneshaw, Al-Sarraj, Safa, Scholz, Sonja W., MacGowan, Daniel J.L., Kirby, Janine, Pioro, Erik P., Pamphlett, Roger, Dunckley, Travis L., Troncoso, Juan C., Moisse, Matthieu, Drory, Vivian E., Turner, Martin R., Blair, Ian P., de Carvalho, Mamede, Hide, Winston, Glass, Jonathan, Mill, Jonathan, Newhouse, Stephen, Pulit, Sara, Robberecht, Wim, Shaw, Pamela, van den Berg, Leonard, Williams, Kelly L., Zatz, Mayana, Rothstein, Jeffrey D., Simmons, Zachary, Van Damme, Philip, Sabatelli, Mario, Trojanowski, John Q., Brown, Robert H., Veldink, Jan H., Tienari, Pentti

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TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A von Brown, Anna-Leigh, Wilkins, Oscar G., Keuss, Matthew J., Hill, Sarah E., Zanovello, Matteo, Lee, Weaverly Colleen, Bampton, Alexander, Lee, Flora C. Y., Masino, Laura, Qi, Yue A., Bryce-Smith, Sam, Gatt, Ariana, Hallegger, Martina, Fagegaltier, Delphine, Phatnani, Hemali, Newcombe, Jia, Gustavsson, Emil K., Seddighi, Sahba, Reyes, Joel F., Coon, Steven L., Ramos, Daniel, Schiavo, Giampietro, Fisher, Elizabeth M. C., Raj, Towfique, Secrier, Maria, Lashley, Tammaryn, Ule, Jernej, Buratti, Emanuele, Humphrey, Jack, Ward, Michael E., Fratta, Pietro

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Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia von Tam, Oliver H., Rozhkov, Nikolay V., Shaw, Regina, Kim, Duyang, Hubbard, Isabel, Fennessey, Samantha, Propp, Nadia, Phatnani, Hemali, Kwan, Justin, Sareen, Dhruv, Broach, James R., Simmons, Zachary, Arcila-Londono, Ximena, Lee, Edward B., Van Deerlin, Vivianna M., Shneider, Neil A., Fraenkel, Ernest, Ostrow, Lyle W., Baas, Frank, Zaitlen, Noah, Berry, James D., Malaspina, Andrea, Fratta, Pietro, Cox, Gregory A., Thompson, Leslie M., Finkbeiner, Steve, Dardiotis, Efthimios, Miller, Timothy M., Chandran, Siddharthan, Pal, Suvankar, Hornstein, Eran, MacGowan, Daniel J., Heiman-Patterson, Terry, Hammell, Molly G., Patsopoulos, Nikolaos.A., Butovsky, Oleg, Dubnau, Joshua, Nath, Avindra, Bowser, Robert, Harms, Matt, Aronica, Eleonora, Poss, Mary, Phillips-Cremins, Jennifer, Crary, John, Atassi, Nazem, Lange, Dale J., Adams, Darius J., Stefanis, Leonidas, Gotkine, Marc, Baloh, Robert, Babu, Suma, Raj, Towfique, Paganoni, Sabrina, Shalem, Ophir, Smith, Colin, Zhang, Bin, Harris, Brent T., Fagegaltier, Delphine, Harris, Brent T., Ostrow, Lyle W., Phatnani, Hemali, Ravits, John, Dubnau, Josh, Gale Hammell, Molly

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Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia von Prudencio, Mercedes, Humphrey, Jack, Pickles, Sarah, Brown, Anna-Leigh, Hill, Sarah E, Kachergus, Jennifer M, Shi, J, Heckman, Michael G, Spiegel, Matthew R, Cook, Casey, Song, Yuping, Yue, Mei, Daughrity, Lillian M, Carlomagno, Yari, Jansen-West, Karen, de Castro, Cristhoper Fernandez, DeTure, Michael, Koga, Shunsuke, Wang, Ying-Chih, Sivakumar, Prasanth, Bodo, Cristian, Candalija, Ana, Talbot, Kevin, Selvaraj, Bhuvaneish T, Burr, Karen, Chandran, Siddharthan, Newcombe, Jia, Lashley, Tammaryn, Hubbard, Isabel, Catalano, Demetra, Kim, Duyang, Propp, Nadia, Fennessey, Samantha, Fagegaltier, Delphine, Phatnani, Hemali, Secrier, Maria, Fisher, Elizabeth Mc, Oskarsson, Björn, van Blitterswijk, Marka, Rademakers, Rosa, Graff-Radford, Neil R, Boeve, Bradley F, Knopman, David S, Petersen, Ronald C, Josephs, Keith A, Thompson, E Aubrey, Raj, Towfique, Ward, Michael, Dickson, Dennis W, Gendron, Tania F, Fratta, Pietro, Petrucelli, Leonard

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Effect of High‐Caloric Nutrition on Survival in Amyotrophic Lateral Sclerosis von Ludolph, Albert C., Dorst, Johannes, Dreyhaupt, Jens, Weishaupt, Jochen H., Kassubek, Jan, Weiland, Ulrike, Meyer, Thomas, Petri, Susanne, Hermann, Andreas, Emmer, Alexander, Grosskreutz, Julian, Grehl, Torsten, Zeller, Daniel, Boentert, Matthias, Schrank, Bertold, Prudlo, Johannes, Winkler, Andrea S., Gorbulev, Stanislav, Roselli, Francesco, Schuster, Joachim, Dupuis, Luc

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Cognitive-behavioral screening reveals prevalent impairment in a large multicenter ALS cohort von Murphy, Jennifer, Factor-Litvak, Pam, Goetz, Raymond, Lomen-Hoerth, Catherine, Nagy, Peter L, Hupf, Jonathan, Singleton, Jessica, Woolley, Susan, Andrews, Howard, Heitzman, Daragh, Bedlack, Richard S, Katz, Jonathan S, Barohn, Richard J, Sorenson, Eric J, Oskarsson, Björn, Fernandes Filho, J. Americo M, Kasarskis, Edward J, Mozaffar, Tahseen, Rollins, Yvonne D, Nations, Sharon P, Swenson, Andrea J, Koczon-Jaremko, Boguslawa A, Mitsumoto, Hiroshi

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Unexpected frequency of the pathogenic AR CAG repeat expansion in the general population von Zanovello, Matteo, Ibáñez, Kristina, Brown, Anna-Leigh, Sivakumar, Prasanth, Bombaci, Alessandro, Santos, Liana, van Vugt, Joke J F A, Narzisi, Giuseppe, Karra, Ramita, Scholz, Sonja W, Ding, Jinhui, Gibbs, J Raphael, Chiò, Adriano, Dalgard, Clifton, Weisburd, Ben, Hanna, Michael G, Greensmith, Linda, Phatnani, Hemali, Veldink, Jan H, Traynor, Bryan J, Polke, James, Houlden, Henry, Fratta, Pietro, Tucci, Arianna

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Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects von Workman, Michael J., Lim, Ryan G., Wu, Jie, Frank, Aaron, Ornelas, Loren, Panther, Lindsay, Galvez, Erick, Perez, Daniel, Meepe, Imara, Lei, Susan, Valencia, Viviana, Gomez, Emilda, Liu, Chunyan, Moran, Ruby, Pinedo, Louis, Tsitkov, Stanislav, Ho, Ritchie, Kaye, Julia A., Thompson, Terri, Rothstein, Jeffrey D., Finkbeiner, Steven, Fraenkel, Ernest, Sareen, Dhruv, Thompson, Leslie M., Svendsen, Clive N.

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Functional network dynamics revealed by EEG microstates reflect cognitive decline in amyotrophic lateral sclerosis von Metzger, Marjorie, Dukic, Stefan, McMackin, Roisin, Giglia, Eileen, Mitchell, Matthew, Bista, Saroj, Costello, Emmet, Peelo, Colm, Tadjine, Yasmine, Sirenko, Vladyslav, Plaitano, Serena, Coffey, Amina, McManus, Lara, Farnell Sharp, Adelais, Mehra, Prabhav, Heverin, Mark, Bede, Peter, Muthuraman, Muthuraman, Pender, Niall, Hardiman, Orla, Nasseroleslami, Bahman

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Predicting functional impairment trajectories in amyotrophic lateral sclerosis: a probabilistic, multifactorial model of disease progression von Tavazzi, Erica, Daberdaku, Sebastian, Zandonà, Alessandro, Vasta, Rosario, Nefussy, Beatrice, Lunetta, Christian, Mora, Gabriele, Mandrioli, Jessica, Grisan, Enrico, Tarlarini, Claudia, Calvo, Andrea, Moglia, Cristina, Drory, Vivian, Gotkine, Marc, Chiò, Adriano, Di Camillo, Barbara

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Integrative transcriptomic analysis of the amyotrophic lateral sclerosis spinal cord implicates glial activation and suggests new risk genes von Humphrey, Jack, Venkatesh, Sanan, Hasan, Rahat, Herb, Jake T., de Paiva Lopes, Katia, Küçükali, Fahri, Byrska-Bishop, Marta, Evani, Uday S., Narzisi, Giuseppe, Fagegaltier, Delphine, Sleegers, Kristel, Phatnani, Hemali, Knowles, David A., Fratta, Pietro, Raj, Towfique

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Temperature Management After Cardiac Arrest: An Advisory Statement by the Advanced Life Support Task Force of the International Liaison Committee on Resuscitation and the American... von Donnino, Michael W, Andersen, Lars W, Berg, Katherine M, Reynolds, Joshua C, Nolan, Jerry P, Morley, Peter T, Lang, Eddy, Cocchi, Michael N, Xanthos, Theodoros, Callaway, Clifton W, Soar, Jasmeet

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Electroencephalographic β-band oscillations in the sensorimotor network reflect motor symptom severity in amyotrophic lateral sclerosis von Dukic, Stefan, Fasano, Antonio, Coffey, Amina, Buxó, Teresa, McMackin, Roisin, Chipika, Rangariroyashe, Heverin, Mark, Bede, Peter, Muthuraman, Muthuraman, Lowery, Madeleine, Carson, Richard G, Hardiman, Orla, Nasseroleslami, Bahman

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Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis von Noyce, Alastair J., Hemani, Gibran, Mora, Gabriele, Bartolomei, Ilaria, Benigni, Michele, Borghero, Giuseppe, Brunetti, Maura, Calvo, Andrea, Cammarosano, Stefania, Cannas, Antonino, Caponnetto, Claudia, Casale, Federico, Cavallaro, Sebastiano, Chiò, Adriano, Colletti, Tiziana, Conforti, Francesca L., Conte, Amelia, Corrado, Lucia, Costantino, Emanuela, D'Alfonso, Sandra, Femiano, Cinzia, Ferrarese, Carlo, Fini, Nicola, Floris, Gianluca, Grassano, Maurizio, Lattante, Serena, Logroscino, Giancarlo, Loi, Daniela, Mancardi, Gianluigi, Mandich, Paola, Manera, Umberto, Marinou, Kalliopi, Marrali, Giuseppe, Marrosu, Maria Giovanna, Mazzini, Letizia, Melis, Maurizio, Messina, Sonia, Mora, Gabriele, Occhineri, Patrizia, Origone, Paola, Pani, Carla, Petrucci, Antonio, Pirisi, Angelo, Restagno, Gabriella, Ricci, Claudia, Riva, Nilo, Sabatelli, Mario, Santarelli, Marialuisa, Spataro, Rossella, Tanel, Raffaella, Tremolizzo, Lucio, Volanti, Paolo, Zollino, Marcella, Arepalli, Sampath, Bowser, Robert, Broach, James, Camu, William, Chia, Ruth, Chiò, Adriano, Ding, Jinhui, Dunckley, Travis L., Eicher, John D., Faghri, Faraz, Feldman, Eva, Fratta, Pietro, Geiger, Joshua T., Gerhard, Glenn, Hardy, John, Harms, Matthew B., Heiman‐Patterson, Terry D., Kamel, Freya, MacGowan, Daniel J.L., Maragakis, Nicholas J., Murphy, Natalie A., Myllykangas, Liisa, Nalls, Mike A., Nicolas, Aude, Orrell, Richard W., Pamphlett, Roger, Pickering‐Brown, Stuart, Pioro, Erik, Pliner, Hannah A., Pulst, Stefan M., Ravits, John M., Rothstein, Jeffrey D., Salvi, Erika, Sendtner, Michael, Simmons, Zachary, Stone, David C., Sulkava, Raimo, Troncoso, Juan C., Van Damme, Philip, Van Deerlin, Vivianna M., Van Den Bosch, Ludo, Zinman, Lorne, Tienari, Pentti J., Stone, David J., Nalls, Mike A., Singleton, Andrew B., Traynor, Bryan J.

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Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis von Dewan, Ramita, Keagle, Pamela, Bacikova, Dagmar, Soltis, Anthony R., Kost, Jason, Colombrita, Claudia, Lewis, Elizabeth A., Pensato, Viviana, Castellotti, Barbara, McLaughlin, Russell L., Comi, Giacomo P., Ceroni, Mauro, Gagliardi, Stella, van Blitterswijk, Marka, Corrado, Lucia, Sorarù, Gianni, Williams, Kelly L., Morrison, Karen E., Veldink, Jan H., Brown, Robert H., Ambrose, John C., Brittain, H., Elgar, Greg, Halai, Dina, Holman, James E., Jackson, Rob, Leong, Ivonne U.S., Maleady-Crowe, Fiona, Mason, Joanne, Riesgo-Ferreiro, Pablo, Rogers, Tim, Watters, Sarah A., Arepalli, Sampath, Chiò, Adriano, Dunckley, Travis L., Faghri, Faraz, Feldman, Eva, Floeter, Mary Kay, Gerhard, Glenn, Jansson, Lilja, Kirby, Janine, Mora, Gabriele, Nalls, Mike A., Pulst, Stefan M., Ravits, John M., Renton, Alan E., Robberecht, Wim, Robey, Ian, Dols-Icardo, Oriol, Illán-Gala, Ignacio, Lleó, Alberto, Khoshnood, Behzad, Sorbi, Sandro, Pastor, Pau, Bigio, Eileen H., Black, Sandra E., Brunetti, Maura, Canosa, Antonio, Gan-Or, Ziv, Goate, Alison, Hupalo, Daniel, Infante, Jon, Kaufmann, Horacio, Kim, Ronald C., Krüger, Rejko, Logroscino, Giancarlo, Love, Seth, Mao, Qinwen, Masliah, Eliezer, Pletnikova, Olga, Reynolds, Regina H., Scherzer, Clemens R., Serrano, Geidy E., Xiromerisiou, Georgia, Phatnani, Hemali, Kwan, Justin, Broach, James R., Arcila-Londono, Ximena, Malaspina, Andrea, Thompson, Leslie M., Dardiotis, Efthimios, Chandran, Siddharthan, Butovsky, Oleg, Dubnau, Joshua, Harms, Matt, Poss, Mary, Phillips-Cremins, Jennifer, Altschuler, Steven, Hu, Michele T.M., Leigh, P. Nigel, Massey, Luke A., Pavese, Nicola, Vaughan, Jenny, Rowe, James B., Ghidoni, Roberta, Ryten, Mina, Tanaka, Toshiko, Ferrucci, Luigi, Vonsattel, Jean Paul, Landers, John E.

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Genome-wide identification of the genetic basis of amyotrophic lateral sclerosis von Zhang, Sai, Cooper-Knock, Johnathan, Weimer, Annika K., Shi, Minyi, Moll, Tobias, Marshall, Jack N.G., Harvey, Calum, Nezhad, Helia Ghahremani, Franklin, John, Souza, Cleide dos Santos, Ning, Ke, Wang, Cheng, Li, Jingjing, Dilliott, Allison A., Farhan, Sali, Elhaik, Eran, Pasniceanu, Iris, Livesey, Matthew R., Eitan, Chen, Hornstein, Eran, Kenna, Kevin P., Blair, Ian, Wray, Naomi R., Kiernan, Matthew, Mitne Neto, Miguel, Chio, Adriano, Cauchi, Ruben, Robberecht, Wim, van Damme, Philip, Corcia, Philippe, Couratier, Philippe, Hardiman, Orla, McLaughin, Russell, Gotkine, Marc, Drory, Vivian, Ticozzi, Nicola, Silani, Vincenzo, Veldink, Jan H., van den Berg, Leonard H., de Carvalho, Mamede, Mora Pardina, Jesus S., Povedano, Monica, Andersen, Peter, Weber, Markus, Başak, Nazli A., Al-Chalabi, Ammar, Shaw, Chris, Shaw, Pamela J., Morrison, Karen E., Landers, John E., Glass, Jonathan D., Veldink, Jan H., Ferraiuolo, Laura, Shaw, Pamela J., Snyder, Michael P.

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Genetic variability in sporadic amyotrophic lateral sclerosis von Van Daele, Sien Hilde, Moisse, Matthieu, van Vugt, Joke J F A, Zwamborn, Ramona A J, van der Spek, Rick, van Rheenen, Wouter, Van Eijk, Kristel, Kenna, Kevin, Corcia, Philippe, Vourc'h, Patrick, Couratier, Philippe, Hardiman, Orla, McLaughin, Russell, Gotkine, Marc, Drory, Vivian, Ticozzi, Nicola, Silani, Vincenzo, Ratti, Antonia, de Carvalho, Mamede, Mora Pardina, Jesús S, Povedano, Monica, Andersen, Peter M, Weber, Markus, Başak, Nazli A, Shaw, Chris, Shaw, Pamela J, Morrison, Karen E, Landers, John E, Glass, Jonathan D, van Es, Michael A, van den Berg, Leonard H, Al-Chalabi, Ammar, Veldink, Jan, Van Damme, Philip

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Revised Airlie House consensus guidelines for design and implementation of ALS clinical trials von van den Berg, Leonard H, Sorenson, Eric, Gronseth, Gary, Macklin, Eric A, Andrews, Jinsy, Baloh, Robert H, Benatar, Michael, Berry, James D, Chio, Adriano, Corcia, Philippe, Genge, Angela, Gubitz, Amelie K, Lomen-Hoerth, Catherine, McDermott, Christopher J, Pioro, Erik P, Rosenfeld, Jeffrey, Silani, Vincenzo, Turner, Martin R, Weber, Markus, Brooks, Benjamin Rix, Miller, Robert G, Mitsumoto, Hiroshi

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Adaptive Platform Trials to Transform Amyotrophic Lateral Sclerosis Therapy Development von Chase, Marianne, Sherman, Alexander V., Shefner, Jeremy, Chibnik, Lori B., Vestrucci, Matteo, Cudkowicz, Merit E., Macklin, Eric, Saville, Ben, Detry, Michelle A., Chibnik, Lori, Bind, Marie Abele, Paganoni, Sabrina, Nicholson, Katie, Ajroud‐Driss, Senda, Kolb, Stephen, (Simpson) Greene, Ericka, Thonhoff, Jason, Shroff, Sheetal, Goutman, Stephen A., Feldman, Eva L., Amber Malcolm, N. P., Newman, Daniel S., Owegi, Margaret Ayo, Ghasemi, Mehdi, Fernandes, Joseph Americo M., Thaisetthawatkul, Pariwat, Rad, Nassim, Ilieva, Hristelina, Judith Guarnieri, N. P., Jacobsen, Bill, Bowser, Robert, Foster, Laura, Rosenfeld, Jeffrey, Bhuvaneswaran, Karthikeyan, Quinn, Colin, Julia Yasek, N. P., Fee, Dominic, Deboo, Anahita, Swenson, Andrea, Nance, Christopher, Vu, Tuan, Suresh, Niraja, Caress, Jim, Cartwright, Michael, McIlduff, Courtney, Stommel, Elijah, Glass, Jonathan, Young, Eufrosina, Wymer, James P., Granit, Volkan, Lewis, Richard, Maragakis, Nicholas J., Clawson, Lora, Uchil, Alpa, Riley, Kristen, Mosmiller, Betsy, Twydell, Paul, Goyal, Namita A., Jabari, Duaa, Kasarskis, Edward J., Shah, Jaimin, Bedlack, Richard, Li, Xiaoyan, Olney, Nicholas, Pattee, Gary L., Johnson, Kristin, Govindarajan, Raghav, Jones, Vovanti, Chase, Marianne, Sherman, Alex, Eydinov, Matthew, Korin, Alexander, Novak, Ilya, Sinani, Ervin, Katsovskiy, Igor, Whitworth, Isaac, Gladden, Catherine, Tustison, Eric, Jentoft, Katie, Lim, Sangwon, Changkuon, Genevive, Figueroa‐Szostek, Precious, Pothier, Lindsay, DiStefano, Sofia, Kennedy, Erin, Bailey, Abbey, Feulner, Jacob, Gomes, Jassira, DiMarzio, Marisa, Henrique, Jennifer, Grabert, Stacey, Garozzo, Tessa, Randall, Rebecca, Connolly, Mariah, De Santiago, Diana, Lavery, Courtney, Hamilton, Jenny, Small, Catherine, Bulat, Allison, McGarry, Andrew

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Project MinE: study design and pilot analyses of a large-scale whole-genome sequencing study in amyotrophic lateral sclerosis von Wouter Van Rheenen, Pulit, Sara L, Dekker, Annelot M, Ahmad Al Khleifat, Brands, William J, Iacoangeli, Alfredo, Kenna, Kevin P, Kavak, Ersen, Kooyman, Maarten, McLaughlin, Russell L, Middelkoop, Bas, Moisse, Matthieu, Schellevis, Raymond D, Shatunov, Aleksey, Sproviero, William, Tazelaar, Gijs H P, Rick A A Van der Spek, Perry T C Van Doormaal, Van Eijk, Kristel R, Joke Van Vugt, Basak, A Nazli, Blair, Ian P, Glass, Jonathan D, Hardiman, Orla, Hide, Winston, Landers, John E, Mora, Jesus S, Morrison, Karen E, Newhouse, Stephen, Robberecht, Wim, Shaw, Christopher E, Shaw, Pamela J, Philip Van Damme, Van Es, Michael A, Wray, Naomi R, Al-Chalabi, Ammar, Leonard H Van den Berg, Veldink, Jan H

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