Phase I and II Study of the Safety, Virologic Effect, and Pharmacokinetics/Pharmacodynamics of Single-Dose 3-O-(3′,3′-Dimethylsuccinyl)Betulinic Acid (Bevirimat) against Human Immu... von Smith, Patrick F, Ogundele, Abayomi, Forrest, Alan, Wilton, John, Salzwedel, Karl, Doto, Judy, Allaway, Graham P, Martin, David E

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Susceptibility of Human Immunodeficiency Virus Type 1 to the Maturation Inhibitor Bevirimat Is Modulated by Baseline Polymorphisms in Gag Spacer Peptide 1 von VAN BAELEN, Kurt, SALZWEDEL, Karl, RONDELEZ, Evelien, VAN EYGEN, Veerle, DE VOS, Stephanie, VERHEYEN, Ann, STEEGEN, Kim, VERLINDEN, Yvan, ALLAWAY, Graham P, STUYVER, Lieven J

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Potent activity of the HIV-1 maturation inhibitor bevirimat in SCID-hu Thy/Liv mice von Stoddart, Cheryl A, Joshi, Pheroze, Sloan, Barbara, Bare, Jennifer C, Smith, Philip C, Allaway, Graham P, Wild, Carl T, Martin, David E

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Direct Evidence that C-Peptide Inhibitors of Human Immunodeficiency Virus Type 1 Entry Bind to the gp41 N-Helical Domain in Receptor-Activated Viral Envelope von Kilgore, Nicole R, Salzwedel, Karl, Reddick, Mary, Allaway, Graham P, Wild, Carl T

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CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5 von Trkola, Alexandra, Dragic, Tatjana, Arthos, James, Binley, James M, Olson, William C, Allaway, Graham P, Cheng-Mayer, Cecilia, Robinson, James, Maddon, Paul J, Moore, John P

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Anti-AIDS Agents. 78. Design, Synthesis, Metabolic Stability Assessment, and Antiviral Evaluation of Novel Betulinic Acid Derivatives as Potent Anti-Human Immunodeficiency Virus (H... von Qian, Keduo, Yu, Donglei, Chen, Chin-Ho, Huang, Li, Morris-Natschke, Susan L, Nitz, Theodore J, Salzwedel, Karl, Reddick, Mary, Allaway, Graham P, Lee, Kuo-Hsiung

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HIV-1 entry into CD4 + cells is mediated by the chemokine receptor CC-CKR-5 von Dragic, Tatjana, Litwin, Virginia, Allaway, Graham P, Martin, Scott R, Huang, Yaoxing, Nagashima, Kirsten A, Cayanan, Charmagne, Maddon, Paul J, Koup, Richard A, Moore, John P, Paxton, William A

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Bevirimat: A Novel Maturation Inhibitor for the Treatment of HIV-1 Infection von Martin, David E, Salzwedel, Karl, Allaway, Graham P

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AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor von Donzella, George A, Schols, Dominique, Lin, Steven W, Esté, José A, Nagashima, Kirsten A, Maddon, Paul J, Allaway, Graham P, Sakmar, Thomas P, Henson, Geoffrey, DeClercq, Erik, Moore, John P

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Elevated temperature triggers human respiratory syncytial virus F protein six-helix bundle formation von Yunus, Abdul S, Jackson, Trent P, Crisafi, Katherine, Burimski, Irina, Kilgore, Nicole R, Zoumplis, Dorian, Allaway, Graham P, Wild, Carl T, Salzwedel, Karl

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Determinants of activity of the HIV-1 maturation inhibitor PA-457 von Li, Feng, Zoumplis, Dorian, Matallana, Claudia, Kilgore, Nicole R., Reddick, Mary, Yunus, Abdul S., Adamson, Catherine S., Salzwedel, Karl, Martin, David E., Allaway, Graham P., Freed, Eric O., Wild, Carl T.

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Anti-AIDS agents 73: Structure–activity relationship study and asymmetric synthesis of 3- O-monomethylsuccinyl-betulinic acid derivatives von Qian, Keduo, Nakagawa-Goto, Kyoko, Yu, Donglei, Morris-Natschke, Susan L., Nitz, Theodore J., Kilgore, Nicole, Allaway, Graham P., Lee, Kuo-Hsiung

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Amino-Terminal Substitutions in the CCR5 Coreceptor Impair gp120 Binding and Human Immunodeficiency Virus Type 1 Entry von Dragic, T, Trkola, A, Lin, S W, Nagashima, K A, Kajumo, F, Zhao, L, Olson, W C, Wu, L, Mackay, C R, Allaway, G P, Sakmar, T P, Moore, J P, Maddon, P J

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The discovery of a class of novel HIV-1 maturation inhibitors and their potential in the therapy of HIV von Yu, Donglei, Wild, Carl T, Martin, David E, Morris-Natschke, Susan L, Chen, Chin-Ho, Allaway, Graham P, Lee, Kuo-Hsiung

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3- O-Glutaryl-dihydrobetulin and related monoacyl derivatives as potent anti-HIV agents von Kashiwada, Yoshiki, Sekiya, Michiko, Ikeshiro, Yasumasa, Fujioka, Toshihiro, Kilgore, Nicole R., Wild, Carl T., Allaway, Graham P., Lee, Kuo-Hsiung

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CD4-Immunoglobulin G2 Protects Hu-PBL-SCID Mice against Challenge by Primary Human Immunodeficiency Virus Type 1 Isolates von Gauduin, M C, Allaway, G P, Olson, W C, Weir, R, Maddon, P J, Koup, R A

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CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5 von Trkola, Alexandra, Dragic, Tatjana, Arthos, James, Binley, James M., Olson, William C., Allaway, Graham P., Cheng-Mayer, Cecilia, Robinson, James, Maddon, Paul J., Moore, John P.

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Development of Bevirimat (PA-457): first-in-class HIV maturation inhibitor von Allaway, Graham P

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Cross-clade neutralization of primary isolates of human immunodeficiency virus type 1 by human monoclonal antibodies and tetrameric CD4-IgG von Trkola, A, Pomales, A B, Yuan, H, Korber, B, Maddon, P J, Allaway, G P, Katinger, H, Barbas, 3rd, C F, Burton, D R, Ho, D D

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Expression and characterization of CD4-IgG2, a novel heterotetramer that neutralizes primary HIV type 1 isolates von ALLAWAY, G. P, DAVIS-BRUNO, K. L, MADDON, P. J, BEAUDRY, G. A, GARCIA, E. B, WONG, E. L, RYDER, A. M, HASEL, K. W, GAUDUIN, M.-C, KOUP, R. A, MCDOUGAL, J. S

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