Shared dependence on the DNA-binding factor TOX for the development of lymphoid tissue–inducer cell and NK cell lineages von Aliahmad, Parinaz, de la Torre, Brian, Kaye, Jonathan

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Safety and immunogenicity of an optimized self-replicating RNA platform for low dose or single dose vaccine applications: a randomized, open label Phase I study in healthy voluntee... von Maine, Christian J., Miyake-Stoner, Shigeki J., Spasova, Darina S., Picarda, Gaelle, Chou, Annie C., Brand, Emily D., Olesiuk, Melanie D., Domingo, Christine C., Little, Hunter J., Goodman, Thomas T., Posy, Jacqueline L., Gonzalez, Jasmin, Bayone, Terrina L., Sparks, Jessica, Gary, Ebony N., Xiang, Zhi, Tursi, Nicholas J., Hojecki, Casey E., Ertl, Hildegund C. J., Weiner, David B., Casmil, Irafasha C., Blakney, Anna K., Essink, Brandon, Somodevilla, Guillermo, Wang, Nathaniel S., Geall, Andrew J., Goldberg, Zelanna, Aliahmad, Parinaz

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Development of all CD4 T lineages requires nuclear factor TOX von Aliahmad, Parinaz, Kaye, Jonathan

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TOX3 is expressed in mammary ER(+) epithelial cells and regulates ER target genes in luminal breast cancer von Seksenyan, Akop, Kadavallore, Asha, Walts, Ann E, de la Torre, Brian, Berel, Dror, Strom, Samuel P, Aliahmad, Parinaz, Funari, Vincent A, Kaye, Jonathan

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876 Self-replicating RNA therapeutics for off-the-shelf precision immunotherapy targeting acquired resistance mutations in low TMB tumors von Goldberg, Zelanna, Maine, Christian, Dailey, Gabrielle P, Domingo, Christine, Picarda, Gaelle, Little, Hunter, Chou, Annie, Sparks, Jessica, Spasova, Darina, Miyake-Stoner, Shigeki, Rabiola, Christopher A, Crosby, Erika J, Hartman, Zachary C, Lyerly, Herbert K, Wang, Nathaniel, Aliahmad, Parinaz

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The many roles of TOX in the immune system von Aliahmad, Parinaz, Seksenyan, Akop, Kaye, Jonathan

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The development of innate lymphoid cells requires TOX-dependent generation of a common innate lymphoid cell progenitor von Seehus, Corey R, Aliahmad, Parinaz, de la Torre, Brian, Iliev, Iliyan D, Spurka, Lindsay, Funari, Vincent A, Kaye, Jonathan

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Next generation self-replicating RNA vectors for vaccines and immunotherapies von Aliahmad, Parinaz, Miyake-Stoner, Shigeki J., Geall, Andrew J., Wang, Nathaniel S.

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TOX is required for development of the CD4 T cell lineage gene program von Aliahmad, Parinaz, Kadavallore, Asha, de la Torre, Brian, Kappes, Dietmar, Kaye, Jonathan

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Self-Replicating RNAs Drive Protective Anti-tumor T Cell Responses to Neoantigen Vaccine Targets in a Combinatorial Approach von Maine, Christian J., Richard, Guilhem, Spasova, Darina S., Miyake-Stoner, Shigeki J., Sparks, Jessica, Moise, Leonard, Sullivan, Ryan P., Garijo, Olivia, Choz, Melissa, Crouse, Jenna M., Aguilar, Allison, Olesiuk, Melanie D., Lyons, Katie, Salvador, Katrina, Blomgren, Melissa, DeHart, Jason L., Kamrud, Kurt I., Berdugo, Gad, De Groot, Anne S., Wang, Nathaniel S., Aliahmad, Parinaz

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CD8+ T cells mediate an NS3-based vaccine protection against Zika virus von Ngono, Annie Elong, Syed, Thasneem, Nguyen, Anh-Viet, Nava, Jose Regla, Susantono, Mercylia, Spasova, Darina, Aguilar, Allison, West, Melissa, Sparks, Jessica, Gonzalez, Andrew, Branche, Emilie, DeHart, Jason L., Kamrud, Kurt, Aliahmad, Parinaz, Wang, Nathaniel, Shresta, Sujan

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Nuclear factor TOX is required for lymph node organogenesis and NK cell development (138.29) von Aliahmad, Parinaz, Kaye, Jonathan

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Innate lymphoid cell development requires TOX-dependent generation of a common ILC progenitor (HEM5P.221) von Seehus, Corey, Aliahmad, Parinaz, de la Torre, Brian, Iliev, Iliyan, Spurka, Lindsay, Funari, Vincent, Kaye, Jonathan

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Differential Requirement for Nuclear Factor TOX in CD4 and CD8 T Cell Lineage Development in the Thymus von Aliahmad, Parinaz, Kaye, Jonathan

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CD8 + T cells mediate protection against Zika virus induced by an NS3-based vaccine von Elong Ngono, Annie, Syed, Thasneem, Nguyen, Anh-Viet, Regla-Nava, Jose Angel, Susantono, Mercylia, Spasova, Darina, Aguilar, Allison, West, Melissa, Sparks, Jessica, Gonzalez, Andrew, Branche, Emilie, DeHart, Jason L, Vega, Jerel Boyd, Karmali, Priya Prakash, Chivukula, Padmanabh, Kamrud, Kurt, Aliahmad, Parinaz, Wang, Nathaniel, Shresta, Sujan

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Innate lymphoid cell development requires TOX-dependent generation of a common ILC progenitor von Seehus, Corey R., Aliahmad, Parinaz, de la Torre, Brian, Iliev, Iliyan D., Spurka, Lindsay, Funari, Vincent A., Kaye, Jonathan

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Development of all CD4 T lineages requires nuclear factor TOX (82.2) von Aliahmad, Parinaz, Kaye, Jonathan

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Abstract 2732: A self-replicating RNA precision medicine approach to therapeutic protein delivery of narrow therapeutic index biomolecules von Goldberg, Zelanna, Maine, Christian, Dailey, Gabrielle P., Domingo, Christine, Picarda, Gaelle, Little, Hunter, Chou, Annie, Sparks, Jessica, Spasova, Darina, Miyake-Stoner, Shigeki, Rabiola, Christopher A., Crosby, Erika J., Hartman, Zachary C., Lyerly, Herbert K., Wang, Nathaniel, Aliahmad, Parinaz

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Abstract 6403: A self-replicating RNA precision medicine approach to overcoming resistance to endocrine therapy in ER+BC von Goldberg, Zelanna, Maine, Christian, Dailey, Gabrielle P., Domingo, Christine, Picarda, Gaelle, Little, Hunter, Chou, Annie, Sparks, Jessica, Spasova, Darina, Miyake-Stoner, Shigeki, Hartman, Zachary C., Rabiola, Christopher A., Crosby, Erika J., Lyerly, Herbert K., Wang, Nathaniel, Aliahmad, Parinaz

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The role of TOX in peripheral T cell subsets (P1121) von Aliahmad, Parinaz, Kadavallore, Asha, Seehus, Corey, de la Torre, Brian, Kaye, Jonathan

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