Discovery of Highly Selective and Potent HDAC3 Inhibitors Based on a 2‑Substituted Benzamide Zinc Binding Group von Liu, Jian, Yu, Younong, Kelly, Joseph, Sha, Deyou, Alhassan, Abdul-Basit, Yu, Wensheng, Maletic, Milana M, Duffy, Joseph L, Klein, Daniel J, Holloway, M. Katharine, Carroll, Steve, Howell, Bonnie J, Barnard, Richard J. O, Wolkenberg, Scott, Kozlowski, Joseph A

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Potent, non-covalent reversible BTK inhibitors with 8-amino-imidazo[1,5-a]pyrazine core featuring 3-position bicyclic ring substitutes von Liu, Jian, Guiadeen, Deodial, Krikorian, Arto, Gao, Xiaolei, Wang, James, Babu Boga, Sobhana, Alhassan, Abdul-Basit, Yu, Wensheng, Selyutin, Oleg, Yu, Younong, Anand, Rajan, Xu, Jiayi, Kelly, Joseph, Duffy, Joseph L., Liu, Shilan, Yang, Chundao, Wu, Hao, Cai, Jiaqiang, Bennett, Chad, Maloney, Kevin M., Tyagarajan, Sriram, Gao, Ying-Duo, Fischmann, Thierry O., Presland, Jeremy, Mansueto, My, Xu, Zangwei, Leccese, Erica, Zhang-Hoover, Jie, Knemeyer, Ian, Garlisi, Charles G., Stivers, Peter, Brandish, Philip E., Hicks, Alexandra, Kim, Ronald, Kozlowski, Joseph A.

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Discovery of 3(S)-thiomethyl pyrrolidine ERK inhibitors for oncology von Boga, Sobhana Babu, Alhassan, Abdul-Basit, Cooper, Alan B., Doll, Ronald, Shih, Neng-Yang, Shipps, Gerald, Deng, Yongqi, Zhu, Hugh, Nan, Yang, Sun, Robert, Zhu, Liang, Desai, Jagdish, Patel, Mehul, Muppalla, Kiran, Gao, Xiaolei, Wang, James, Yao, Xin, Kelly, Joseph, Gudipati, Subrahmanyam, Paliwal, Sunil, Tsui, Hon-Chung, Wang, Tong, Sherborne, Bradley, Xiao, Li, Hruza, Alan, Buevich, Alexei, Zhang, Li-Kang, Hesk, David, Samatar, Ahmed A., Carr, Donna, Long, Brian, Black, Stuart, Dayananth, Priya, Windsor, William, Kirschmeier, Paul, Bishop, Robert

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Discovery of novel BTK inhibitors with carboxylic acids von Gao, Xiaolei, Wang, James, Liu, Jian, Guiadeen, Deodial, Krikorian, Arto, Boga, Sobhana Babu, Alhassan, Abdul-Basit, Selyutin, Oleg, Yu, Wensheng, Yu, Younong, Anand, Rajan, Liu, Shilan, Yang, Chundao, Wu, Hao, Cai, Jiaqiang, Cooper, Alan, Zhu, Hugh, Maloney, Kevin, Gao, Ying-Duo, Fischmann, Thierry O., Presland, Jeremy, Mansueto, My, Xu, Zangwei, Leccese, Erica, Zhang-Hoover, Jie, Knemeyer, Ian, Garlisi, Charles G., Bays, Nathan, Stivers, Peter, Brandish, Philip E., Hicks, Alexandra, Kim, Ronald, Kozlowski, Joeseph A.

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Discovery of 3-morpholino-imidazole[1,5-a]pyrazine BTK inhibitors for rheumatoid arthritis von Boga, Sobhana Babu, Alhassan, Abdul-Basit, Liu, Jian, Guiadeen, Deodial, Krikorian, Arto, Gao, Xiaolei, Wang, James, Yu, Younong, Anand, Rajan, Liu, Shilan, Yang, Chundao, Wu, Hao, Cai, Jiaqiang, Zhu, Hugh, Desai, Jagdish, Maloney, Kevin, Gao, Ying-Duo, Fischmann, Thierry O., Presland, Jeremy, Mansueto, My, Xu, Zangwei, Leccese, Erica, Knemeyer, Ian, Garlisi, Charles G., Bays, Nathan, Stivers, Peter, Brandish, Philip E., Hicks, Alexandra, Cooper, Alan, Kim, Ronald M., Kozlowski, Joseph A.

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Discovery of 8‑Amino-imidazo[1,5‑a]pyrazines as Reversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis von Liu, Jian, Guiadeen, Deodial, Krikorian, Arto, Gao, Xiaolei, Wang, James, Boga, Sobhana Babu, Alhassan, Abdul-Basit, Yu, Younong, Vaccaro, Henry, Liu, Shilan, Yang, Chundao, Wu, Hao, Cooper, Alan, de Man, Jos, Kaptein, Allard, Maloney, Kevin, Hornak, Viktor, Gao, Ying-Duo, Fischmann, Thierry O, Raaijmakers, Hans, Vu-Pham, Diep, Presland, Jeremy, Mansueto, My, Xu, Zangwei, Leccese, Erica, Zhang-Hoover, Jie, Knemeyer, Ian, Garlisi, Charles G, Bays, Nathan, Stivers, Peter, Brandish, Philip E, Hicks, Alexandra, Kim, Ronald, Kozlowski, Joseph A

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[3+2] Cycloaddition-mediated synthesis of 3-methylsulfanyl-pyrrolidine-3-carboxylic acid methyl ester von Boga, Sobhana B., Alhassan, Abdul-Basit, Cooper, Alan B., Shih, Neng-Yang, Doll, Ronald J.

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4-Butyl-1-(2,3,4-tri-O-acetyl-β-l-fuco-pyranos-yl)-1H-1,2,3-triazole von Alhassan, Abdul-Basit, Norris, Peter, Zeller, Matthias

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1,2,3,4-Tetra- O -acetyl-α- L -fucopyranose von Alhassan, Abdul-Basit, Norris, Peter, Zeller, Matthias

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MK-8353: Discovery of an Orally Bioavailable Dual Mechanism ERK Inhibitor for Oncology von Boga, Sobhana Babu, Deng, Yongqi, Zhu, Liang, Nan, Yang, Cooper, Alan B., Shipps, Gerald W., Doll, Ronald, Shih, Neng-Yang, Zhu, Hugh, Sun, Robert, Wang, Tong, Paliwal, Sunil, Tsui, Hon-Chung, Gao, Xiaolei, Yao, Xin, Desai, Jagdish, Wang, James, Alhassan, Abdul Basit, Kelly, Joseph, Patel, Mehul, Muppalla, Kiran, Gudipati, Subrahmanyam, Zhang, Li-Kang, Buevich, Alexei, Hesk, David, Carr, Donna, Dayananth, Priya, Black, Stuart, Mei, Hong, Cox, Kathleen, Sherborne, Bradley, Hruza, Alan W., Xiao, Li, Jin, Weihong, Long, Brian, Liu, Gongjie, Taylor, Stacey A., Kirschmeier, Paul, Windsor, William T., Bishop, Robert, Samatar, Ahmed A.

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Structure-based drug design of clinical compound MK-8353, a novel inhibitor of ERK von Hruza, Alan, Boga, Sobhana Babu, Alhassan, Abdul-Basit, Cooper, Alan B., Doll, Ronald, Shih, Neng-Yang, Shipps, Gerald, Deng, Yongqi, Zhu, Hugh, Nan, Yang, Sun, Robert, Zhu, Liang, Desai, Jagdish, Patel, Mehul, Muppalla, Kiran, Gao, Xiaolei, Wang, James, Kelly, Joseph, Gudipati, Subrahmanyam, Paliwal, Sunil, Tsui, Hon-Chung, Wang, Tong, Sherborne, Bradley, Xiao, Li, Buevich, Alexei, Hesk, David, Samatar, Ahmed A., Carr, Donna, Long, Brian, Black, Stuart, Dayananth, Priya, Windsor, William, Kirschmeier, Paul, Bishop, Robert

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Carbohydrate mimetics for Staphylococcus aureus capsule von Fagan, Diana Lee, Vicarel, Monica L., Alhassan, Abdul‐Basit, Norris, Peter

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BTK INHIBITORS von BOGA, Sobhana Babu, YU, Younong, WU, Hao, ALHASSAN, Abdul-Basit, YANG, Chundao, LIU, Shilan, ANAND, Rajan, KOZLOWSKI, Joseph, A, YU, Wensheng, GUIADEEN, Deodialsingh, LIU, Jian

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BENZAMIDE IMIDAZOPYRAZINE BTK INHIBITORS von WANG, Dahai, WU, Hao, LIU, Shilan, WANG, Jyhshing, KOZLOWSKI, Joseph, A, GUIADEEN, Deodialsingh, LIU, Jian, BOGA, Sobhana Babu, CAI, Jiaqiang, ALHASSAN, Abdul-Basit, YANG, Chundao, YU, Wensheng, GAO, Xiaolei

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4-Butyl-1-(2,3,4-tri- O -acetyl-β- L -fucopyranosyl)-1 H -1,2,3-triazole von Alhassan, Abdul-Basit, Norris, Peter, Zeller, Matthias

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BTK inhibitors von Yu, Younong, Liu, Jian, Anand, Rajan, Guiadeen, Deodial Guy, Yu, Wensheng, Wu, Hao, Liu, Shilan, Alhassan, Abdul-Basit, Yang, Chundao, Kozlowski, Joseph A, Boga, Sobhana Babu

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NOVEL COMPOUNDS THAT ARE ERK INHIBITORS von Gao, , Xiaolei, Lo, , Sie-Mun, Alhassan, , Abdul-Basit, Yao, , Xin, Zhu, , Liang, Boga, , Sobhana Babu, Wang, , James J-S, Zhu, , Hugh, Y, Gudipati, , Subrahmanyam, Shipps, , Gerald, W., Jr, Kelly, , Joseph, M, Deng, , Yongqi, Cooper, , Alan, B, Desai, , Jagdish, A

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1,2,3,4‐Tetra‐O‐acetyl‐α‐l‐fucopyran­ose von Alhassan, Abdul‐Basit, Norris, Peter, Zeller, Matthias

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Benzamide imidazopyrazine Btk inhibitors von Liu, Jian, Yu, Wensheng, Wang, Jyhshing, Gao, Xiaolei, Alhassan, Abdul-Basit, Kozlowski, Joseph A, Guiadeen, Deodial Guy, Wang, Dahai, Wu, Hao, Cai, Jiaqiang, Liu, Shilan, Yang, Chundao, Boga, Sobhana Babu

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derivados de indazol policíclicos e seu uso como inibidores de erk para o tratamento de câncer von Hugh Zhu, Xiaolei Gao, James Wang, Jagdish Desai, Alan Cooper, Gerald W. Shipps, JR, Abdul-Basit Alhassan, Yongqi Deng, Liang Zhu, Hon-Chung Tsui, Neng-Yang Shih, Mehul Patel, Joseph Kelly, Sobhana Babu Boga, Yang Nan, Ronald Doll, Sunil Paliwal

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