Multi-Angle Effector Function Analysis of Human Monoclonal IgG Glycovariants von Dashivets, Tetyana, Thomann, Marco, Rueger, Petra, Knaupp, Alexander, Buchner, Johannes, Schlothauer, Tilman

Volltext

Affinity Capillary Electrophoresis–Mass Spectrometry as a Tool to Unravel Proteoform-Specific Antibody–Receptor Interactions von Gstöttner, Christoph, Hook, Michaela, Christopeit, Tony, Knaupp, Alexander, Schlothauer, Tilman, Reusch, Dietmar, Haberger, Markus, Wuhrer, Manfred, Domínguez-Vega, Elena

Volltext

Heparin chromatography as an in vitro predictor for antibody clearance rate through pinocytosis von Kraft, Thomas E, Richter, Wolfgang F, Emrich, Thomas, Knaupp, Alexander, Schuster, Michaela, Wolfert, Andreas, Kettenberger, Hubert

Volltext

Oxidation in the complementarity-determining regions differentially influences the properties of therapeutic antibodies von Dashivets, Tetyana, Stracke, Jan, Dengl, Stefan, Knaupp, Alexander, Pollmann, Jan, Buchner, Johannes, Schlothauer, Tilman

Volltext

A novel approach to investigate the effect of methionine oxidation on pharmacokinetic properties of therapeutic antibodies von Stracke, Jan, Emrich, Thomas, Rueger, Petra, Schlothauer, Tilman, Kling, Lothar, Knaupp, Alexander, Hertenberger, Hubert, Wolfert, Andreas, Spick, Christian, Lau, Wilma, Drabner, Georg, Reiff, Ulrike, Koll, Hans, Papadimitriou, Apollon

Volltext

Affinity capillary electrophoresis – mass spectrometry permits direct binding assessment of IgG and FcγRIIa in a glycoform-resolved manner von Gstöttner, Christoph, Knaupp, Alexander, Vidarsson, Gestur, Reusch, Dietmar, Schlothauer, Tilman, Wuhrer, Manfred, Domínguez-Vega, Elena

Volltext

Function-structure approach reveals novel insights on the interplay of Immunoglobulin G 1 proteoforms and Fc gamma receptor IIa allotypes von Lippold, Steffen, Mistry, Karishma, Lenka, Sunidhi, Whang, Kevin, Liu, Peilu, Pitschi, Sebastian, Kuhne, Felix, Reusch, Dietmar, Cadang, Lance, Knaupp, Alexander, Izadi, Saeed, Dunkle, Alexis, Yang, Feng, Schlothauer, Tilman

Volltext

Fc gamma receptor IIIb binding of individual antibody proteoforms resolved by affinity chromatography-mass spectrometry von Lippold, Steffen, Knaupp, Alexander, de Ru, Arnoud H, Tjokrodirijo, Rayman T N, van Veelen, Peter A, van Puijenbroek, Erwin, de Taeye, Steven W, Reusch, Dietmar, Vidarsson, Gestur, Wuhrer, Manfred, Schlothauer, Tilman, Falck, David

Volltext

Extending the performance of FcRn and FcγRIIIa affinity liquid chromatography for protein biopharmaceuticals von Bouvarel, Thomas, Duivelshof, Bastiaan L., Camperi, Julien, Schlothauer, Tilman, Knaupp, Alexander, Stella, Cinzia, Guillarme, Davy

Volltext

CD3 Target Affinity Chromatography Mass Spectrometry as a New Tool for Function–Structure Characterization of T‑Cell Engaging Bispecific Antibody Proteoforms and Product-Related Va... von Lippold, Steffen, Hook, Michaela, Spick, Christian, Knaupp, Alexander, Whang, Kevin, Ruperti, Fabian, Cadang, Lance, Andersen, Nisana, Vogt, Annette, Grote, Michael, Reusch, Dietmar, Haberger, Markus, Yang, Feng, Schlothauer, Tilman

Volltext

Affinity capillary electrophoresis - mass spectrometry permits direct binding assessment of IgG and FcγRIIa in a glycoform-resolved manner von Gstöttner, Christoph, Knaupp, Alexander, Vidarsson, Gestur, Reusch, Dietmar, Schlothauer, Tilman, Wuhrer, Manfred, Domínguez-Vega, Elena

Volltext

Enhancing Selectivity of Protein Biopharmaceuticals in Ion Exchange Chromatography through Addition of Organic Modifiers von Duivelshof, Bastiaan Laurens, Bouvarel, Thomas, Pirner, Sebastian, Larraillet, Vincent, Knaupp, Alexander, Koll, Hans, D'Atri, Valentina, Guillarme, Davy

Volltext

Development of C1q Affinity Chromatography for the Study of C1q-IgG Interactions von Marshall, Michael J E, Knaupp, Alexander, Spick, Christian, Koese, Ilker, Maier, Maria, Cragg, Mark S, Cymer, Florian, Schlothauer, Tilman

Volltext

Evaluation of an FcRn affinity chromatographic method for IgG1-type antibodies and evaluation of IgG variants von Cymer, Florian, Schlothauer, Tilman, Knaupp, Alexander, Beck, Hermann

Volltext

Radiolabeled IgG antibodies: Impact of various labels on neonatal Fc receptor binding von Edelmann, Martin R., Kettenberger, Hubert, Knaupp, Alexander, Schlothauer, Tilman, Otteneder, Michael B.

Volltext

Multi-Angle Effector Function Analysis of Human Monoclonal IgG Glycovariants: e0143520 von Dashivets, Tetyana, Thomann, Marco, Rueger, Petra, Knaupp, Alexander, Buchner, Johannes, Schlothauer, Tilman

Volltext

ANTIBODIES BINDING TO CD3 AND FOLR1 von GEIGER, Martina, KNAUPP, Alexander, KLEIN, Christian, BRUENKER, Peter

Volltext bestellen

COMPLEMENT FACTOR BASED AFFINITY CHROMATOGRAPHY von LARIVIERE, Laurent, KNAUPP, Alexander, SCHLOTHAUER, Tilman, RUEGER, Petra, SEEBER, Stefan

Volltext bestellen

COMPLEMENT FACTOR BASED AFFINITY CHROMATOGRAPHY von LARIVIERE, Laurent, KNAUPP, Alexander, SCHLOTHAUER, Tilman, RUEGER, Petra, SEEBER, Stefan

Volltext bestellen

COMPLEMENT FACTOR BASED AFFINITY CHROMATOGRAPHY von LARIVIERE, Laurent, KNAUPP, Alexander, SCHLOTHAUER, Tilman, RUEGER, Petra, SEEBER, Stefan

Volltext bestellen