Functional profiling reveals critical role for miRNA in differentiation of human mesenchymal stem cells von Schoolmeesters, Angela, Eklund, Teresa, Leake, Devin, Vermeulen, Annaleen, Smith, Queta, Force Aldred, Shelley, Fedorov, Yuriy

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An abundance of bidirectional promoters in the human genome von Trinklein, Nathan D, Aldred, Shelley Force, Hartman, Sara J, Schroeder, Diane I, Otillar, Robert P, Myers, Richard M

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Multispecific Antibody Development Platform Based on Human Heavy Chain Antibodies von Clarke, Starlynn C, Ma, Biao, Trinklein, Nathan D, Schellenberger, Ute, Osborn, Michael J, Ouisse, Laure-Hélène, Boudreau, Andrew, Davison, Laura M, Harris, Katherine E, Ugamraj, Harshad S, Balasubramani, Aarti, Dang, Kevin H, Jorgensen, Brett, Ogana, Heather Anne N, Pham, Duy T, Pratap, Payal P, Sankaran, Preethi, Anegon, Ignacio, van Schooten, Wim C, Brüggemann, Marianne, Buelow, Roland, Force Aldred, Shelley

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Genome-wide discovery of drug-dependent human liver regulatory elements von Smith, Robin P, Eckalbar, Walter L, Morrissey, Kari M, Luizon, Marcelo R, Hoffmann, Thomas J, Sun, Xuefeng, Jones, Stacy L, Force Aldred, Shelley, Ramamoorthy, Anuradha, Desta, Zeruesenay, Liu, Yunlong, Skaar, Todd C, Trinklein, Nathan D, Giacomini, Kathleen M, Ahituv, Nadav

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Polymorphisms within the C-Reactive Protein (CRP) Promoter Region Are Associated with Plasma CRP Levels von Carlson, Christopher S., Aldred, Shelley Force, Lee, Philip K., Tracy, Russell P., Schwartz, Stephen M., Rieder, Mark, Liu, Kiang, Williams, O. Dale, Iribarren, Carlos, Lewis, E. Cora, Fornage, Myriam, Boerwinkle, Eric, Gross, Myron, Jaquish, Cashell, Nickerson, Deborah A., Myers, Richard M., Siscovick, David S., Reiner, Alexander P.

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Identification and functional analysis of human transcriptional promoters von Trinklein, Nathan D, Aldred, Shelley J Force, Saldanha, Alok J, Myers, Richard M

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Efficient tumor killing and minimal cytokine release with novel T-cell agonist bispecific antibodies von Trinklein, Nathan D, Pham, Duy, Schellenberger, Ute, Buelow, Ben, Boudreau, Andrew, Choudhry, Priya, Clarke, Starlynn C, Dang, Kevin, Harris, Katherine E, Iyer, Suhasini, Jorgensen, Brett, Pratap, Payal P, Rangaswamy, Udaya S, Ugamraj, Harshad S, Vafa, Omid, Wiita, Arun P, van Schooten, Wim, Buelow, Roland, Force Aldred, Shelley

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Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies von Harris, Katherine E, Aldred, Shelley Force, Davison, Laura M, Ogana, Heather Anne N, Boudreau, Andrew, Brüggemann, Marianne, Osborn, Michael, Ma, Biao, Buelow, Benjamin, Clarke, Starlynn C, Dang, Kevin H, Iyer, Suhasini, Jorgensen, Brett, Pham, Duy T, Pratap, Payal P, Rangaswamy, Udaya S, Schellenberger, Ute, van Schooten, Wim C, Ugamraj, Harshad S, Vafa, Omid, Buelow, Roland, Trinklein, Nathan D

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Two-tiered Approach Identifies a Network of Cancer and Liver Disease-related Genes Regulated by miR-122 von Boutz, Daniel R., Collins, Patrick J., Suresh, Uthra, Lu, Mingzhu, Ramírez, Cristina M., Fernández-Hernando, Carlos, Huang, Yufei, de Sousa Abreu, Raquel, Le, Shu-Yun, Shapiro, Bruce A., Liu, Angela M., Luk, John M., Force Aldred, Shelley, Trinklein, Nathan D., Marcotte, Edward M., Penalva, Luiz O.F.

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Integrated analysis of experimental data sets reveals many novel promoters in 1% of the human genome von Trinklein, Nathan D, Karaöz, Ulaş, Wu, Jiaqian, Halees, Anason, Force Aldred, Shelley, Collins, Patrick J, Zheng, Deyou, Zhang, Zhengdong D, Gerstein, Mark B, Snyder, Michael, Myers, Richard M, Weng, Zhiping

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High-throughput microRNA target screening: miR-122 case study von Collins, Patrick, Rose, Michael, Aldred, Shelley Force, Trinklein, Nathan

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Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project von Birney, Ewan, Stamatoyannopoulos, John A, Dutta, Anindya, Guigó, Roderic, Gingeras, Thomas R, Margulies, Elliott H, Weng, Zhiping, Snyder, Michael, Dermitzakis, Emmanouil T, Thurman, Robert E, Kuehn, Michael S, Taylor, Christopher M, Neph, Shane, Koch, Christoph M, Asthana, Saurabh, Malhotra, Ankit, Adzhubei, Ivan, Greenbaum, Jason A, Andrews, Robert M, Flicek, Paul, Boyle, Patrick J, Cao, Hua, Carter, Nigel P, Clelland, Gayle K, Davis, Sean, Day, Nathan, Dhami, Pawandeep, Dillon, Shane C, Dorschner, Michael O, Fiegler, Heike, Giresi, Paul G, Goldy, Jeff, Hawrylycz, Michael, Haydock, Andrew, Humbert, Richard, James, Keith D, Johnson, Brett E, Johnson, Ericka M, Frum, Tristan T, Rosenzweig, Elizabeth R, Karnani, Neerja, Lee, Kirsten, Lefebvre, Gregory C, Navas, Patrick A, Neri, Fidencio, Parker, Stephen C J, Sabo, Peter J, Sandstrom, Richard, Shafer, Anthony, Vetrie, David, Weaver, Molly, Wilcox, Sarah, Yu, Man, Collins, Francis S, Dekker, Job, Lieb, Jason D, Tullius, Thomas D, Crawford, Gregory E, Sunyaev, Shamil, Noble, William S, Dunham, Ian, Denoeud, France, Reymond, Alexandre, Kapranov, Philipp, Rozowsky, Joel, Zheng, Deyou, Castelo, Robert, Frankish, Adam, Harrow, Jennifer, Ghosh, Srinka, Sandelin, Albin, Hofacker, Ivo L, Baertsch, Robert, Keefe, Damian, Dike, Sujit, Cheng, Jill, Hirsch, Heather A, Sekinger, Edward A, Lagarde, Julien, Abril, Josep F, Shahab, Atif, Flamm, Christoph, Fried, Claudia, Hackermüller, Jörg, Hertel, Jana, Lindemeyer, Manja, Missal, Kristin, Tanzer, Andrea, Washietl, Stefan, Korbel, Jan, Emanuelsson, Olof, Pedersen, Jakob S, Holroyd, Nancy, Taylor, Ruth, Swarbreck, David, Matthews, Nicholas, Dickson, Mark C, Thomas, Daryl J, Weirauch, Matthew T, Gilbert, James

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Functional analysis of transcription factor binding sites in human promoters von Whitfield, Troy W, Wang, Jie, Collins, Patrick J, Partridge, E Christopher, Aldred, Shelley Force, Trinklein, Nathan D, Myers, Richard M, Weng, Zhiping

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When monoclonal antibodies are not monospecific: Hybridomas frequently express additional functional variable regions von Bradbury, Andrew R M, Trinklein, Nathan D, Thie, Holger, Wilkinson, Ian C, Tandon, Atul K, Anderson, Stephen, Bladen, Catherine L, Jones, Brittany, Aldred, Shelley Force, Bestagno, Marco, Burrone, Oscar, Maynard, Jennifer, Ferrara, Fortunato, Trimmer, James S, Görnemann, Janina, Glanville, Jacob, Wolf, Philipp, Frenzel, Andre, Wong, Julin, Koh, Xin Yu, Eng, Hui-Yan, Lane, David, Lefranc, Marie-Paule, Clark, Mike, Dübel, Stefan

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TNB-486, a Novel Fully Human Bispecific CD19 x CD3 Antibody That Kills CD19-Positive Tumor Cells with Minimal Cytokine Secretion von Malik, Harbani, Buelow, Ben, Rangaswamy, Udaya, Balasubramani, Aarti, Boudreau, Andrew, Dang, Kevin, Davison, Laura, Force Aldred, Shelley, Harris, Katherine Marie, Iyer, Suhasini, Jorgensen, Brett, Pham, Duy, Prabhakar, Kirthana, Schellenberger, Ute, Ugamraj, Harshad, Trinklein, Nathan, Van Schooten, Wim

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Abstract LB-090: Sequence-based discovery of fully human anti-CD3 and anti-PDL1 single domain antibodies using novel transgenic rats von Trinklein, Nathan, Force Aldred, Shelley, Schellenberger, Ute, Harris, Kat, Clarke, Starlynn, Dang, Kevin, Pham, Duy, Bruggemann, Marianne, vanSchooten, Wim

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Identifying targets of human micrornas with the LightSwitch Luciferase Assay System using 3'UTR-reporter constructs and a microRNA mimic in adherent cells von Aldred, Shelley Force, Collins, Patrick, Trinklein, Nathan

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Evaluation of monovalent versus biparatopic CD3xPSMA bispecific antibodies for t-cell mediated killing of prostate tumor cells with minimal cytokine release von Buelow, Ben, Clarke, Starlynn, Dang, Kevin, Li, Jacky, Rancan, Chiara, Li, Yuping, Sankaran, Preethi, Pham, Duy, Balasubramani, Aarti, Davison, Laura, Harris, Katherine, Jorgensen, Brett, Schellenberger, Ute, Trinklein, Nathan, Ugamraj, Harshad, Fong, Lawrence, Van Schooten, Wim, Force Aldred, Shelley

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A novel CD3xPSMA bispecific antibody for efficient T cell mediated killing of prostate tumor cells with minimal cytokine release von Clarke, Starlynn, Dang, Kevin, Li, Yuping, Sankaran, Preethi, Pham, Duy, Balasubramani, Aarti, Davison, Laura, Harris, Katherine, Jorgensen, Brett, Schellenberger, Ute, Trinklein, Nathan, Ugamraj, Harshad, Buelow, Roland, Van Schooten, Wim, Force Aldred, Shelley, Buelow, Ben

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Ex Vivo Assessment of Tnb-383B, a Bcma-Bispecific Antibody, Against Primary Tumor and Endogenous T Cells from Relapsing Multiple Myeloma Patients von Foureau, David M., Bhutani, Manisha, Robinson, Myra, Guo, Fei, Pham, Duy, Force Aldred, Shelley, Buelow, Ben, Rigby, Katherine, Tjaden, Elise, Leonidas, Marina, Atrash, Shebli, Ndiaye, Ami P, Symanowski, James, Voorhees, Peter M., Usmani, Saad Z.

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