Using the molecular classification of glioblastoma to inform personalized treatment von Olar, Adriana, Aldape, Kenneth D

Volltext

Big data in basic and translational cancer research von Jiang, Peng, Sinha, Sanju, Aldape, Kenneth, Hannenhalli, Sridhar, Sahinalp, Cenk, Ruppin, Eytan

Volltext

Insights From Molecular Profiling of Adult Glioma von Diamandis, Phedias, Aldape, Kenneth D

Volltext

Mosaic Amplification of Multiple Receptor Tyrosine Kinase Genes in Glioblastoma von Snuderl, Matija, Fazlollahi, Ladan, Le, Long P., Nitta, Mai, Zhelyazkova, Boryana H., Davidson, Christian J., Akhavanfard, Sara, Cahill, Daniel P., Aldape, Kenneth D., Betensky, Rebecca A., Louis, David N., Iafrate, A. John

Volltext

Glioblastoma: pathology, molecular mechanisms and markers von Aldape, Kenneth, Zadeh, Gelareh, Mansouri, Sheila, Reifenberger, Guido, von Deimling, Andreas

Volltext

cIMPACT‐NOW update 7: advancing the molecular classification of ependymal tumors von Ellison, David W., Aldape, Kenneth D., Capper, David, Fouladi, Maryam, Gilbert, Mark R., Gilbertson, Richard J., Hawkins, Cynthia, Merchant, Thomas E., Pajtler, Kristian, Venneti, Sriram, Louis, David N.

Volltext

DNA methylation profiling as a model for discovery and precision diagnostics in neuro-oncology von Pratt, Drew, Sahm, Felix, Aldape, Kenneth

Volltext

Phase I Study of DNX-2401 (Delta-24-RGD) Oncolytic Adenovirus: Replication and Immunotherapeutic Effects in Recurrent Malignant Glioma von Lang, Frederick F, Conrad, Charles, Gomez-Manzano, Candelaria, Yung, W K Alfred, Sawaya, Raymond, Weinberg, Jeffrey S, Prabhu, Sujit S, Rao, Ganesh, Fuller, Gregory N, Aldape, Kenneth D, Gumin, Joy, Vence, Luis M, Wistuba, Ignacio, Rodriguez-Canales, Jaime, Villalobos, Pamela A, Dirven, Clemens M F, Tejada, Sonia, Valle, Ricardo D, Alonso, Marta M, Ewald, Brett, Peterkin, Joanna J, Tufaro, Frank, Fueyo, Juan

Volltext

MGMT promoter methylation status testing to guide therapy for glioblastoma: refining the approach based on emerging evidence and current challenges von Mansouri, Alireza, Hachem, Laureen D, Mansouri, Sheila, Nassiri, Farshad, Laperriere, Normand J, Xia, Daniel, Lindeman, Neal I, Wen, Patrick Y, Chakravarti, Arnab, Mehta, Minesh P, Hegi, Monika E, Stupp, Roger, Aldape, Kenneth D, Zadeh, Gelareh

Volltext

Dose-Dense Temozolomide for Newly Diagnosed Glioblastoma: A Randomized Phase III Clinical Trial von GILBERT, Mark R, MEIHUA WANG, MAHAJAN, Anita, SCHULTZ, Christopher J, ERRIDGE, Sara, BAUMERT, Brigitta, HOPKINS, Kristen I, TZUK-SHINA, Tzahala, BROWN, Paul D, CHAKRAVARTI, Arnab, CURRAN, Walter J, MEHTA, Minesh P, ALDAPE, Kenneth D, STUPP, Roger, HEGI, Monika E, JAECKLE, Kurt A, ARMSTRONG, Terri S, WEFEL, Jeffrey S, MINHEE WON, BLUMENTHAL, Deborah T

Volltext

A Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma von Gilbert, Mark R, Dignam, James J, Armstrong, Terri S, Wefel, Jeffrey S, Blumenthal, Deborah T, Vogelbaum, Michael A, Colman, Howard, Chakravarti, Arnab, Pugh, Stephanie, Won, Minhee, Jeraj, Robert, Brown, Paul D, Jaeckle, Kurt A, Schiff, David, Stieber, Volker W, Brachman, David G, Werner-Wasik, Maria, Tremont-Lukats, Ivo W, Sulman, Erik P, Aldape, Kenneth D, Curran, Walter J, Mehta, Minesh P

Volltext

Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth von Zhang, Lin, Zhang, Siyuan, Yao, Jun, Lowery, Frank J., Zhang, Qingling, Huang, Wen-Chien, Li, Ping, Li, Min, Wang, Xiao, Zhang, Chenyu, Wang, Hai, Ellis, Kenneth, Cheerathodi, Mujeeburahiman, McCarty, Joseph H., Palmieri, Diane, Saunus, Jodi, Lakhani, Sunil, Huang, Suyun, Sahin, Aysegul A., Aldape, Kenneth D., Steeg, Patricia S., Yu, Dihua

Volltext

TERT Promoter Mutations and Risk of Recurrence in Meningioma von Sahm, Felix, Schrimpf, Daniel, Olar, Adriana, Koelsche, Christian, Reuss, David, Bissel, Juliane, Kratz, Annekathrin, Capper, David, Schefzyk, Sebastian, Hielscher, Thomas, Wang, Qianghu, Sulman, Erik P, Adeberg, Sebastian, Koch, Arend, Okuducu, Ali Fuat, Brehmer, Stefanie, Schittenhelm, Jens, Becker, Albert, Brokinkel, Benjamin, Schmidt, Melissa, Ull, Theresa, Gousias, Konstantinos, Kessler, Almuth Friederike, Lamszus, Katrin, Debus, Jürgen, Mawrin, Christian, Kim, Yoo-Jin, Simon, Matthias, Ketter, Ralf, Paulus, Werner, Aldape, Kenneth D, Herold-Mende, Christel, von Deimling, Andreas

Volltext

Estimation of cell lineages in tumors from spatial transcriptomics data von Ru, Beibei, Huang, Jinlin, Zhang, Yu, Aldape, Kenneth, Jiang, Peng

Volltext

The evolving role of molecular markers in the diagnosis and management of diffuse glioma von Huse, Jason T, Aldape, Kenneth D

Volltext

Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis von Li, Xinjian, Jiang, Yuhui, Meisenhelder, Jill, Yang, Weiwei, Hawke, David H., Zheng, Yanhua, Xia, Yan, Aldape, Kenneth, He, Jie, Hunter, Tony, Wang, Liwei, Lu, Zhimin

Volltext

Molecular classification and grading of meningioma von Nasrallah, MacLean P., Aldape, Kenneth D.

Volltext

IDH mutation status and role of WHO grade and mitotic index in overall survival in grade II–III diffuse gliomas von Olar, Adriana, Wani, Khalida M., Alfaro-Munoz, Kristin D., Heathcock, Lindsey E., van Thuijl, Hinke F., Gilbert, Mark R., Armstrong, Terri S., Sulman, Erik P., Cahill, Daniel P., Vera-Bolanos, Elizabeth, Yuan, Ying, Reijneveld, Jaap C., Ylstra, Bauke, Wesseling, Pieter, Aldape, Kenneth D.

Volltext

Detection and discrimination of intracranial tumors using plasma cell-free DNA methylomes von Nassiri, Farshad, Chakravarthy, Ankur, Feng, Shengrui, Shen, Shu Yi, Nejad, Romina, Zuccato, Jeffrey A., Voisin, Mathew R., Patil, Vikas, Horbinski, Craig, Aldape, Kenneth, Zadeh, Gelareh, De Carvalho, Daniel D.

Volltext

ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect von Yang, Weiwei, Zheng, Yanhua, Xia, Yan, Ji, Haitao, Chen, Xiaomin, Guo, Fang, Lyssiotis, Costas A., Aldape, Kenneth, Cantley, Lewis C., Lu, Zhimin

Volltext