Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts von Fry, David W, Harvey, Patricia J, Keller, Paul R, Elliott, William L, Meade, Maryanne, Trachet, Erin, Albassam, Mudher, Zheng, XianXian, Leopold, Wilbur R, Pryer, Nancy K, Toogood, Peter L

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Application of Imaging Techniques to Cases of Drug-Induced Crystal Nephropathy in Preclinical Studies von Lenz, Barbara, Brink, Andreas, Siam, Monira, De Paepe, Anne, Bassett, Simon, Eichinger-Chapelon, Anne, Maliver, Pierre, Neff, Rachel, Niederhauser, Urs, Steinhuber, Bernd, Zurbach, Raphael, Singer, Thomas, Funk, Christoph, Schuler, Franz, Albassam, Mudher, Schadt, Simone

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Quantitative Histological Assessment of Xenobiotic-Induced Liver Enzyme Induction and Pituitary-Thyroid Axis Stimulation in Rats Using Whole-Slide Automated Image Analysis von Garrido, Rosario, Zabka, Tanja S., Tao, Jianhua, Fielden, Mark, Fretland, Adrian, Albassam, Mudher

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Characterization of Xenobiotic-Induced Hepatocellular Enzyme Induction in Rats: Anticipated Thyroid Effects and Unique Pituitary Gland Findings von Zabka, Tanja S., Fielden, Mark R., Garrido, Rosario, Tao, Jianhua, Fretland, Adrian J., Fretland, Jennifer L., Albassam, Mudher A., Singer, Thomas, Kolaja, Kyle L.

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Spontaneous Cardiomyopathy in Cynomolgus Monkeys (Macaca Fascicularis) von Zabka, Tanja S., Irwin, Michael, Albassam, Mudher A.

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Susceptibility of rats to corneal lesions after injectable anesthesia von Turner, P.V, Albassam, M.A

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Comparative methods for multiplex analysis of cytokine protein expression in plasma of lipopolysaccharide-treated mice von Bobrowski, Walter F., McDuffie, J. Eric, Sobocinski, Gregg, Chupka, Jonathan, Olle, Eric, Bowman, Amy, Albassam, Mudher

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Drug-induced Obstructive and Retrograde Nephropathy Associated with α2u-globulin in Male Rats von Jacobsen, Björn, Freichel, Christian, Eichinger-Chapelon, Anne, Brink, Andreas, Hoflack, Jean-Christophe, Albassam, Mudher, Lenz, Barbara

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Current Challenges and Controversies in Drug-Induced Liver Injury von Corsini, Alberto, Ganey, Patricia, Ju, Cynthia, Kaplowitz, Neil, Pessayre, Dominique, Roth, Robert, Watkins, Paul B, Albassam, Mudher, Liu, Baolian, Stancic, Saray, Suter, Laura, Bortolini, Michele

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Current Challenges and Controversies in Drug-Induced Liver Injury von Corsini, Alberto, Ganey, Patricia, Ju, Cynthia, Kaplowitz, Neil, Pessayre, Dominique, Roth, Robert, Watkins, Paul B., Albassam, Mudher, Liu, Baolian, Stancic, Saray, Suter, Laura, Bortolini, Michele

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The Minipig is a Suitable Non-Rodent Model in the Safety Assessment of Single Stranded Oligonucleotides von Braendli-Baiocco, A, Festag, M, Dumong-Erichsen, K, Persson, R, Mihatsch, MJ, Fisker, N, Funk, J, Mohr, S, Constien, R, Ploix, C, Brady, K, Berrera, M, Altmann, B, Lenz, B, Albassam, M, Schmitt, G, Weiser, T, Schuler, F, Singer, T, Tessier, Y

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Immunogenicity, Inflammation, and Lipid Accumulation in Cynomolgus Monkeys Infused with a Lipidated Tetranectin-ApoA-I Fusion Protein von Regenass-Lechner, Franziska, Staack, Roland F, Mary, Jean-Luc, Richter, Wolfgang F, Winter, Michael, Jordan, Gregor, Justies, Nicole, Langenkamp, Anja, Garrido, Rosario, Albassam, Mudher, Singer, Thomas, Atzpodien, Elke-Astrid

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Subchronic Toxicity of Atorvastatin, a Hydroxymethylglutaryl-Coenzyme A Reductase Inhibitor, in Beagle Dogs von Walsh, Kathleen M., Albassam, Mudher A., Clarke, David E.

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Temporal Patterns of Novel Circulating Biomarkers in IL-2-mediated Vascular Injury in the Rat von Keirstead, Natalie D., Bertinetti-Lapatki, Cristina, Knapp, Denise, Albassam, Mudher, Hughes, Valerie, Hong, Feng, Roth, Adrian B., Mikaelian, Igor

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From the Cover: The Minipig is a Suitable Non-Rodent Model in the Safety Assessment of Single Stranded Oligonucleotides von Braendli-Baiocco, Annamaria, Festag, Matthias, Dumong Erichsen, Kamille, Persson, Robert, Mihatsch, Michael J, Fisker, Niels, Funk, Juergen, Mohr, Susanne, Constien, Rainer, Ploix, Corinne, Brady, Kevin, Berrera, Marco, Altmann, Bernd, Lenz, Barbara, Albassam, Mudher, Schmitt, Georg, Weiser, Thomas, Schuler, Franz, Singer, Thomas, Tessier, Yann

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Differentiating Spontaneous from Drug-Induced Vascular Injury in the Dog von Clemo, Frances A.S., Evering, Winston E., Snyder, Paul W., Albassam, Mudher A.

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Key components of the mode of action for hemangiosarcoma induction in pregabalin-treated mice: evidence of increased bicarbonate, dysregulated erythropoiesis, macrophage activation... von Criswell, Kay A, Wojcinski, Zbigniew, Pegg, David, Albassam, Mudher, Duddy, Steven, Olsen, Eric, Bailie, Marc, Foote, Stephen, Anderson, Timothy

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Coronary Arteriopathy in Monkeys Following Administration of CI-1020, an Endothelin A Receptor Antagonist von Albassam, Mudher A., Metz, Alan L., Gragtmans, Norbert J., King, Lena M., Macallum, Grace E., Hallak, Hussein, McGuire, Edward J.

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Authors’ Response to Letter to the Editor on “Image Cytometry Protocols” von Garrido, Rosario, Zabka, Tanja S., Tao, Jianhua, Fielden, Mark R., Fretland, Adrian J., Albassam, Mudher

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A STEPWISE METHOD FOR THE ISOLATION OF ENDOTHELIAL CELLS AND SMOOTH MUSCLE CELLS FROM INDIVIDUAL CANINE CORONARY ARTERIES von DAME, MICHAEL K, YU, XINWEN, GARRIDO, ROSARIO, BOBROWSKI, WALTER, ERIC MCDUFFIE, J, MURPHY, HEDWIG S, ALBASSAM, MUDHER, VARANI, JAMES

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