Gene Expression and Pharmacodynamic Changes in 1,760 Systemic Lupus Erythematosus Patients From Two Phase III Trials of BAFF Blockade With Tabalumab von Hoffman, Robert W., Merrill, Joan T., Alarcón‐Riquelme, Marta M. E., Petri, Michelle, Dow, Ernst R., Nantz, Eric, Nisenbaum, Laura K., Schroeder, Krista M., Komocsar, Wendy J., Perumal, Narayanan B., Linnik, Matthew D., Airey, David C., Liu, Yushi, Rocha, Guilherme V., Higgs, Richard E.

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Genetic analysis of the pathogenic molecular sub-phenotype interferon-alpha identifies multiple novel loci involved in systemic lupus erythematosus von Kariuki, S N, Ghodke-Puranik, Y, Dorschner, J M, Chrabot, B S, Kelly, J A, Tsao, B P, Kimberly, R P, Alarcón-Riquelme, M E, Jacob, C O, Criswell, L A, Sivils, K L, Langefeld, C D, Harley, J B, Skol, A D, Niewold, T B

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CymeR: cytometry analysis using KNIME, docker and R von Muchmore, B, Alarcón-Riquelme, M E

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MHC associations with clinical and autoantibody manifestations in European SLE von Morris, D L, Fernando, M M A, Taylor, K E, Chung, S A, Nititham, J, Alarcón-Riquelme, M E, Barcellos, L F, Behrens, T W, Cotsapas, C, Gaffney, P M, Graham, R R, Pons-Estel, B A, Gregersen, P K, Harley, J B, Hauser, S L, Hom, G, Langefeld, C D, Noble, J A, Rioux, J D, Seldin, M F, Vyse, T J, Criswell, L A

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STAT4 associates with systemic lupus erythematosus through two independent effects that correlate with gene expression and act additively with IRF5 to increase risk von Abelson, A-K, Delgado-Vega, A M, Kozyrev, S V, Sánchez, E, Velázquez-Cruz, R, Eriksson, N, Wojcik, J, Linga Reddy, M V P, Lima, G, D’Alfonso, S, Migliaresi, S, Baca, V, Orozco, L, Witte, T, Ortego-Centeno, N, Abderrahim, H, Pons-Estel, B A, Gutiérrez, C, Suárez, A, González-Escribano, M F, Martin, J, Alarcón-Riquelme, M E

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The dual effect of the lupus-associated polymorphism rs10516487 on BANK1 gene expression and protein localization von Kozyrev, S V, Bernal-Quirós, M, Alarcón-Riquelme, M E, Castillejo-López, C

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PO.1.2 Bank1 has a determinant role in the presence of age-associated b cells in autoimmunity von Gómez Hernández, G, Morell Hita, M, Alarcón Riquelme, M

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Polymorphisms within the ARNT2 and CX3CR1 Genes Are Associated with the Risk of Developing Invasive Aspergillosis von Lupiañez, C B, Martínez-Bueno, M, Sánchez-Maldonado, J M, Badiola, J, Cunha, C, Springer, J, Lackner, M, Segura-Catena, J, Canet, L M, Alcazar-Fuoli, L, López-Nevot, M A, Fianchi, L, Aguado, J M, Pagano, L, López-Fernández, E, Alarcón-Riquelme, M, Potenza, L, Gonçalves, S M, Luppi, M, Moratalla, L, Solano, C, Sampedro, A, González-Sierra, P, Cuenca-Estrella, M, Lagrou, K, Maertens, J A, Lass-Flörl, C, Einsele, H, Vazquez, L, Loeffler, J, Ríos-Tamayo, R, Carvalho, A, Jurado, M, Sainz, J

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GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region von Armstrong, D L, Zidovetzki, R, Alarcón-Riquelme, M E, Tsao, B P, Criswell, L A, Kimberly, R P, Harley, J B, Sivils, K L, Vyse, T J, Gaffney, P M, Langefeld, C D, Jacob, C O

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No evidence of association of the PDCD1 gene with Type 1 diabetes von Fawwaz, S., Nikamo, P., Törn, C., Landin-Olsson, M., Lernmark, Å., Alarcón-Riquelme, M., Kockum, I.

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The R620W C T polymorphism of the gene PTPN22 is associated with SLE independently of the association of PDCD1 von Reddy, M V Prasad Linga, Johansson, M, Sturfelt, G, Jönsen, A, Gunnarsson, I, Svenungsson, E, Rantapää-Dahlqvist, S, Alarcón-Riquelme, M E

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Association of UCP2 −866 G A polymorphism with chronic inflammatory diseases von Yu, X, Wieczorek, S, Franke, A, Yin, H, Pierer, M, Sina, C, Karlsen, T H, Boberg, K M, Bergquist, A, Kunz, M, Witte, T, Gross, W L, Epplen, J T, Alarcón-Riquelme, M E, Schreiber, S, Ibrahim, S M

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Corrigendum to ‘Distinct gene dysregulation patterns herald precision medicine potentiality in systemic lupus erythematosus’ [J. Autoimmun. 136 (April 2023) 103025] von Lindblom, Julius, Toro-Domínguez, Daniel, Carnero-Montoro, Elena, Beretta, Lorenzo, Borghi, Maria Orietta, Castillo, Jessica, Enman, Yvonne, Mohan, Chandra, Alarcón-Riquelme, Marta E., Barturen, Guillermo, Parodis, Ioannis

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Genetic association of miRNA-146a with systemic lupus erythematosus in Europeans through decreased expression of the gene von Löfgren, S E, Frostegård, J, Truedsson, L, Pons-Estel, B A, D'Alfonso, S, Witte, T, Lauwerys, B R, Endreffy, E, Kovács, L, Vasconcelos, C, Martins da Silva, B, Kozyrev, S V, Alarcón-Riquelme, M E

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Genetic aspects of rheumatic diseases von Steinsson, K., Alarcón-Riquelme, M. E.

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Genetic association of CD247 (CD3ζ) with SLE in a large-scale multiethnic study von Martins, M, Williams, A H, Comeau, M, Marion, M, Ziegler, J T, Freedman, B I, Merrill, J T, Glenn, S B, Kelly, J A, Sivils, K M, James, J A, Guthridge, J M, Alarcón-Riquelme, M E, Bae, S-C, Kim, J-H, Kim, D, Anaya, J-M, Boackle, S A, Criswell, L A, Kimberly, R P, Alarcón, G S, Brown, E E, Vilá, L M, Petri, M A, Ramsey-Goldman, R, Niewold, T B, Tsao, B P, Gilkeson, G S, Kamen, D L, Jacob, C O, Stevens, A M, Gaffney, P M, Harley, J B, Langefeld, C D, Fesel, C

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PO.1.5 Scoring personalized molecular portraits identify systemic lupus erythematosus subtypesand predict transcriptional drug responses, symptomatology and disease progression von Toro Dominguez, D, Martínez Bueno, M, López Domínguez, R, Martorell Marugan, J, Carnero Montoro, E, Barturen, G, Goldman, D, Petri, M, Carmona Saez, P, Alarcón-Riquelme, M

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PO.5.99 Drug repurposing for treating lupus nephritis based on transcriptome profiling and autoimmunity-related serological markers von Parodis, I, Lindblom, J, Toro-Domínguez, D, Carnero-Montoro, E, Borghi, MO, Castillo, J, Enman, Y, Repsilber, D, Mohan, C, Alarcón-Riquelme, M, Barturen, G

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PO.1.12 Transcriptome profiling and autoimmunity-related serological markers identify TP53 and C3aR as drug targets in neuropsychiatric systemic lupus erythematosus von Lindblom, J, Toro-Domínguez, D, Carnero-Montoro, E, Borghi, MO, Castillo, J, Iacobaeus, E, Enman, Y, Repsilber, D, Mohan, C, Alarcón-Riquelme, M, Barturen, G, Parodis, I

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Study of the role of functional variants of SLC22A4, RUNX1 and SUMO4 in systemic lupus erythematosus von Orozco, G, Sánchez, E, Gómez, L M, González-Gay, M A, López-Nevot, M A, Torres, B, Ortego-Centeno, N, Jiménez-Alonso, J, de Ramón, E, Sánchez Román, J, Anaya, J M, Sturfelt, G, Gunnarsson, I, Svennungsson, E, Alarcón-Riquelme, M, González-Escribano, M F, Martín, J

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