Catching a resurgence: Increase in SARS-CoV-2 viral RNA identified in wastewater 48 h before COVID-19 clinical tests and 96 h before hospitalizations von D'Aoust, Patrick M., Graber, Tyson E., Mercier, Elisabeth, Montpetit, Danika, Alexandrov, Ilya, Neault, Nafisa, Baig, Aiman Tariq, Mayne, Janice, Zhang, Xu, Alain, Tommy, Servos, Mark R., Srikanthan, Nivetha, MacKenzie, Malcolm, Figeys, Daniel, Manuel, Douglas, Jüni, Peter, MacKenzie, Alex E., Delatolla, Robert

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mTORC1 Controls Mitochondrial Activity and Biogenesis through 4E-BP-Dependent Translational Regulation von Morita, Masahiro, Gravel, Simon-Pierre, Chénard, Valérie, Sikström, Kristina, Zheng, Liang, Alain, Tommy, Gandin, Valentina, Avizonis, Daina, Arguello, Meztli, Zakaria, Chadi, McLaughlan, Shannon, Nouet, Yann, Pause, Arnim, Pollak, Michael, Gottlieb, Eyal, Larsson, Ola, St-Pierre, Julie, Topisirovic, Ivan, Sonenberg, Nahum

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Transcriptional profiling of macrophages reveals distinct parasite stage-driven signatures during early infection by Leishmania donovani von Chaparro, Visnu, Graber, Tyson E., Alain, Tommy, Jaramillo, Maritza

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Ionizing Radiation and Translation Control: A Link to Radiation Hormesis? von Kabilan, Usha, Graber, Tyson E., Alain, Tommy, Klokov, Dmitry

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Distinct perturbation of the translatome by the antidiabetic drug metformin von Larsson, Ola, Morita, Masahiro, Topisirovic, Ivan, Alain, Tommy, Blouin, Marie-Jose, Pollak, Michael, Sonenberg, Nahum

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La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1) von Fonseca, Bruno D., Zakaria, Chadi, Jia, Jian-Jun, Graber, Tyson E., Svitkin, Yuri, Tahmasebi, Soroush, Healy, Danielle, Hoang, Huy-Dung, Jensen, Jacob M., Diao, Ilo T., Lussier, Alexandre, Dajadian, Christopher, Padmanabhan, Niranjan, Wang, Walter, Matta-Camacho, Edna, Hearnden, Jaclyn, Smith, Ewan M., Tsukumo, Yoshinori, Yanagiya, Akiko, Morita, Masahiro, Petroulakis, Emmanuel, González, Jose L., Hernández, Greco, Alain, Tommy, Damgaard, Christian K.

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Smac mimetics synergize with immune checkpoint inhibitors to promote tumour immunity against glioblastoma von Beug, Shawn T., Beauregard, Caroline E., Healy, Cristin, Sanda, Tarun, St-Jean, Martine, Chabot, Janelle, Walker, Danielle E., Mohan, Aditya, Earl, Nathalie, Lun, Xueqing, Senger, Donna L., Robbins, Stephen M., Staeheli, Peter, Forsyth, Peter A., Alain, Tommy, LaCasse, Eric C., Korneluk, Robert G.

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Translation control during prolonged mTORC1 inhibition mediated by 4E-BP3 von Tsukumo, Yoshinori, Alain, Tommy, Fonseca, Bruno D., Nadon, Robert, Sonenberg, Nahum

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La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs von Lahr, Roni M, Fonseca, Bruno D, Ciotti, Gabrielle E, Al-Ashtal, Hiba A, Jia, Jian-Jun, Niklaus, Marius R, Blagden, Sarah P, Alain, Tommy, Berman, Andrea J

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Translational Control of Entrainment and Synchrony of the Suprachiasmatic Circadian Clock by mTOR/4E-BP1 Signaling von Cao, Ruifeng, Robinson, Barry, Xu, Haiyan, Gkogkas, Christos, Khoutorsky, Arkady, Alain, Tommy, Yanagiya, Akiko, Nevarko, Tatiana, Liu, Andrew C., Amir, Shimon, Sonenberg, Nahum

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Oral reovirus reshapes the gut microbiome and enhances antitumor immunity in colon cancer von Lee, Won Suk, Lee, Seung Joon, Lee, Hye Jin, Yang, Hannah, Go, Eun-Jin, Gansukh, Enkhtaivan, Song, Ki-Hoon, Xiang, Xiao, Park, Dong Guk, Alain, Tommy, Chon, Hong Jae, Kim, Chan

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Cap-binding protein 4EHP effects translation silencing by microRNAs von Chapat, Clément, Jafarnejad, Seyed Mehdi, Matta-Camacho, Edna, Hesketh, Geoffrey G., Gelbart, Idit A., Attig, Jan, Gkogkas, Christos G., Alain, Tommy, Stern-Ginossar, Noam, Fabian, Marc R., Gingras, Anne-Claude, Duchaine, Thomas F., Sonenberg, Nahum

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eIF4E/4E-BP ratio predicts the efficacy of mTOR targeted therapies von Alain, Tommy, Morita, Masahiro, Fonseca, Bruno D, Yanagiya, Akiko, Siddiqui, Nadeem, Bhat, Mamatha, Zammit, Domenick, Marcus, Victoria, Metrakos, Peter, Voyer, Lucie-Anne, Gandin, Valentina, Liu, Yi, Topisirovic, Ivan, Sonenberg, Nahum

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LARP1 on TOP of ribosome production von Fonseca, Bruno D., Lahr, Roni M., Damgaard, Christian K., Alain, Tommy, Berman, Andrea J.

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Astrocytes and the tumor microenvironment inflammatory state dictate the killing of glioblastoma cells by Smac mimetic compounds von Malone, Kyle, Dugas, Melanie, Earl, Nathalie, Alain, Tommy, LaCasse, Eric C., Beug, Shawn T.

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Polysome fractionation and analysis of mammalian translatomes on a genome-wide scale von Gandin, Valentina, Sikström, Kristina, Alain, Tommy, Morita, Masahiro, McLaughlan, Shannon, Larsson, Ola, Topisirovic, Ivan

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Identification of Novel Regulators of Radiosensitivity Using High-Throughput Genetic Screening von Tamaddondoust, Rosette N, Wong, Alicia, Chandrashekhar, Megha, Azzam, Edouard I, Alain, Tommy, Wang, Yi

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Synthetic virology approaches to improve the safety and efficacy of oncolytic virus therapies von Azad, Taha, Rezaei, Reza, Singaravelu, Ragunath, Pelin, Adrian, Boulton, Stephen, Petryk, Julia, Onsu, Kemal Alper, Martin, Nikolas T., Hoskin, Victoria, Ghahremani, Mina, Marotel, Marie, Marius, Ricardo, He, Xiaohong, Crupi, Mathieu J. F., Hoang, Huy-Dung, Nik-Akhtar, Abolfazl, Ahmadi, Mahsa, Zamani, Nika Kooshki, Golshani, Ashkan, Alain, Tommy, Greer, Peter, Ardolino, Michele, Dickinson, Bryan C., Tai, Lee-Hwa, Ilkow, Carolina S., Bell, John C.

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A Novel 4EHP-GIGYF2 Translational Repressor Complex Is Essential for Mammalian Development von Morita, Masahiro, Ler, Lian Wee, Fabian, Marc R., Siddiqui, Nadeem, Mullin, Michael, Henderson, Valerie C., Alain, Tommy, Fonseca, Bruno D., Karashchuk, Galina, Bennett, Christopher F., Kabuta, Tomohiro, Higashi, Shinji, Larsson, Ola, Topisirovic, Ivan, Smith, Robert J., Gingras, Anne-Claude, Sonenberg, Nahum

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Translational profiling of macrophages infected with Leishmania donovani identifies mTOR- and eIF4A-sensitive immune-related transcripts von Chaparro, Visnu, Leroux, Louis-Philippe, Masvidal, Laia, Lorent, Julie, Graber, Tyson E., Zimmermann, Aude, Duque, Guillermo Arango, Descoteaux, Albert, Alain, Tommy, Larsson, Ola, Jaramillo, Maritza

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