Discovery of PF-00217830: Aryl piperazine napthyridinones as D₂ partial agonists for schizophrenia and bipolar disorder von Johnson, Douglas S, Choi, Chung, Fay, Lorraine K, Favor, David A, Repine, Joseph T, White, Andrew D, Akunne, Hyacinth C, Fitzgerald, Lawrence, Nicholls, Kim, Snyder, Bradley J, Whetzel, Steven Z, Zhang, Liming, Serpa, Kevin A

Volltext

Affinity for Dopamine D2, D3, and D4 Receptors of 2-Aminotetralins. Relevance of D2 Agonist Binding for Determination of Receptor Subtype Selectivity von van Vliet, L. Alexander, Tepper, Pieter G, Dijkstra, Durk, Damsma, Geert, Wikström, Håkan, Pugsley, Thomas A, Akunne, Hyacinth C, Heffner, Thomas G, Glase, Shelly A, Wise, Lawrence D

Volltext

A Series of 6- and 7-Piperazinyl- and -Piperidinylmethylbenzoxazinones with Dopamine D4 Antagonist Activity:  Discovery of a Potential Atypical Antipsychotic Agent von Belliotti, Thomas R, Wustrow, David J, Brink, Wouter A, Zoski, Kim T, Shih, Yu-Hsin, Whetzel, Steven Z, Georgic, Lynn M, Corbin, Ann E, Akunne, Hyacinth C, Heffner, Thomas G, Pugsley, Thomas A, Wise, Lawrence D

Volltext

Discovery of PF-00217830: Aryl piperazine napthyridinones as D 2 partial agonists for schizophrenia and bipolar disorder von Johnson, Douglas S., Choi, Chung, Fay, Lorraine K., Favor, David A., Repine, Joseph T., White, Andrew D., Akunne, Hyacinth C., Fitzgerald, Lawrence, Nicholls, Kim, Snyder, Bradley J., Whetzel, Steven Z., Zhang, Liming, Serpa, Kevin A.

Volltext

Aryl 1-But-3-ynyl-4-phenyl-1,2,3,6-tetrahydropyridines as Potential Antipsychotic Agents:  Synthesis and Structure−Activity Relationships von Glase, Shelly A, Akunne, Hyacinth C, Heffner, Thomas G, Jaen, Juan C, MacKenzie, Robert G, Meltzer, Leonard T, Pugsley, Thomas A, Smith, Sarah J, Wise, Lawrence D

Volltext

Design and Structure-Activity Relationships of C-Terminal Cyclic Neurotensin Fragment Analogs von Sefler, Andrea M, He, John X, Sawyer, Tomi K, Holub, Katherine E, Omecinsky, Diana O, Reily, Michael D, Thanabal, Venkataraman, Akunne, Hyacinth C, Cody, Wayne L

Volltext

3-Arylimino-2-indolones Are Potent and Selective Galanin GAL3 Receptor Antagonists von Konkel, Michael J, Lagu, Bharat, Boteju, Lakmal W, Jimenez, Hermogenes, Noble, Stewart, Walker, Mary W, Chandrasena, Gamini, Blackburn, Thomas P, Nikam, Sham S, Wright, Jon L, Kornberg, Brian E, Gregory, Tracy, Pugsley, Thomas A, Akunne, Hyacinth, Zoski, Kim, Wise, Lawrence D

Volltext

Discovery of PF-00217830: Aryl piperazine napthyridinones as D sub(2 partial agonists for schizophrenia and bipolar disorder) von Johnson, Douglas S, Choi, Chung, Fay, Lorraine K, Favor, David A, Repine, Joseph T, White, Andrew D, Akunne, Hyacinth C, Fitzgerald, Lawrence, Nicholls, Kim, Snyder, Bradley J, Whetzel, Steven Z, Zhang, Liming, Serpa, Kevin A

Volltext

Substituted [(4-Phenylpiperazinyl)- methyl]benzamides:  Selective Dopamine D 4 Agonists von Glase, Shelly A., Akunne, Hyacinth C., Georgic, Lynn M., Heffner, Thomas G., MacKenzie, Robert G., Manley, Peter J., Pugsley, Thomas A., Wise, Lawrence D.

Volltext

3-Arylimino-2-indolones Are Potent and Selective Galanin GAL 3 Receptor Antagonists von Konkel, Michael J., Lagu, Bharat, Boteju, Lakmal W., Jimenez, Hermogenes, Noble, Stewart, Walker, Mary W., Chandrasena, Gamini, Blackburn, Thomas P., Nikam, Sham S., Wright, Jon L., Kornberg, Brian E., Gregory, Tracy, Pugsley, Thomas A., Akunne, Hyacinth, Zoski, Kim, Wise, Lawrence D.

Volltext

3-arylimino-2-indolones are potent and selective galanin GAL3receptor antagonists von KONKEL, Michael J, LAGU, Bharat, KORNBERG, Brian E, GREGORY, Tracy, PUGSLEY, Thomas A, AKUNNE, Hyacinth, ZOSKI, Kim, WISE, Lawrence D, BOTEJU, Lakmal W, JIMENEZ, Hermogenes, NOBLE, Stewart, WALKER, Mary W, CHANDRASENA, Gamini, BLACKBURN, Thomas P, NIKAM, Sham S, WRIGHT, Jon L

Volltext

Substituted [(4-Phenylpiperazinyl)- methyl]benzamides:  Selective Dopamine D4 Agonists von Glase, Shelly A, Akunne, Hyacinth C, Georgic, Lynn M, Heffner, Thomas G, MacKenzie, Robert G, Manley, Peter J, Pugsley, Thomas A, Wise, Lawrence D

Volltext

Affinity for Dopamine D 2 , D 3 , and D 4 Receptors of 2-Aminotetralins. Relevance of D 2 Agonist Binding for Determination of Receptor Subtype Selectivity von van Vliet, L. Alexander, Tepper, Pieter G., Dijkstra, Durk, Damsma, Geert, Wikström, Håkan, Pugsley, Thomas A., Akunne, Hyacinth C., Heffner, Thomas G., Glase, Shelly A., Wise, Lawrence D.

Volltext

Pyrazolo[1,5-a]pyrimidine CRF-1 receptor antagonists von Wustrow, David J., Capiris, Thomas, Rubin, Ronald, Knobelsdorf, James A., Akunne, Hyacinth, Davis, M.Duff, MacKenzie, Robert, Pugsley, Thomas A., Zoski, Kim T., Heffner, Thomas G., Wise, Lawrence D.

Volltext

GBR12909 antagonizes the ability of cocaine to elevate extracellular levels of dopamine von Rothman, Richard B., Mele, Andrea, Reid, Audrey A., Akunne, Hyacinth C., Greig, Nigel, Thurkauf, Andrew, de Costa, Brian R., Rice, Kenner C., Pert, Agu

Volltext

The discovery of PD 89211 and related compounds: Selective dopamine D4 receptor antagonists von Pugsley, Thomas A, Shih, Yu Hsin, Whetzel, Steven Z, Zoski, Kim, Van Leeuwen, Don, Akunne, Hyacinth, Mackenzie, R, Heffner, Thomas G, Wustrow, David, Wise, Lawrence D

Volltext

Aminopyrimidines with High Affinity for Both Serotonin and Dopamine Receptors von Wustrow, David, Belliotti, Thomas, Glase, Shelly, Kesten, Suzanne Ross, Johnson, Don, Colbry, Norman, Rubin, Ronald, Blackburn, Anthony, Akunne, Hyacinth, Corbin, Ann, Davis, M. Duff, Georgic, Lynn, Whetzel, Steven, Zoski, Kim, Heffner, Thomas, Pugsley, Thomas, Wise, Lawrence

Volltext

Identification of a GBR12935 homolog, LR1111, which is over 4,000-fold selective for the dopamine transporter, relative to serotonin and norepinephrine transporters von Rothman, Richard B., Lewis, Bruce, Dersch, Chris, Xu, Heng, Radesca, Lillian, De Costa, Brian R., Rice, Kenner C., Kilburn, Robert B., Akunne, Hyacinth C., Pert, Agu

Volltext

Serotonin modulation of pain responsiveness in the aged rat von Akunne, Hyacinth C., Soliman, Karam F.A.

Volltext

Characterization of binding of [ 3H]PD 128907, A selective Dopamine D 3 receptor agonist ligand, to CHO-K1 cells von Akunne, Hyacinth C., Towers, Patrick, Ellis, Gareth J., Dijkstra, Durk, Wikström, Håkan, Heffner, Thomas G., Wise, Lawrence D., Pugsley, Thomas A.

Volltext