In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice von El Refaey, Mona, Xu, Li, Gao, Yandi, Canan, Benjamin D, Adesanya, T.M Ayodele, Warner, Sarah C, Akagi, Keiko, Symer, David E, Mohler, Peter J, Ma, Jianjie, Janssen, Paul M.L, Han, Renzhi

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Human papillomavirus and the landscape of secondary genetic alterations in oral cancers von Gillison, Maura L, Akagi, Keiko, Xiao, Weihong, Jiang, Bo, Pickard, Robert K L, Li, Jingfeng, Swanson, Benjamin J, Agrawal, Amit D, Zucker, Mark, Stache-Crain, Birgit, Emde, Anne-Katrin, Geiger, Heather M, Robine, Nicolas, Coombes, Kevin R, Symer, David E

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Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability von Akagi, Keiko, Li, Jingfeng, Broutian, Tatevik R, Padilla-Nash, Hesed, Xiao, Weihong, Jiang, Bo, Rocco, James W, Teknos, Theodoros N, Kumar, Bhavna, Wangsa, Danny, He, Dandan, Ried, Thomas, Symer, David E, Gillison, Maura L

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HPV integration hijacks and multimerizes a cellular enhancer to generate a viral-cellular super-enhancer that drives high viral oncogene expression von Warburton, Alix, Redmond, Catherine J, Dooley, Katharine E, Fu, Haiqing, Gillison, Maura L, Akagi, Keiko, Symer, David E, Aladjem, Mirit I, McBride, Alison A

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Chromatin states shape insertion profiles of the piggyBac, Tol2 and Sleeping Beauty transposons and murine leukemia virus von Yoshida, Junko, Akagi, Keiko, Misawa, Ryo, Kokubu, Chikara, Takeda, Junji, Horie, Kyoji

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Synthetic viability by BRCA2 and PARP1/ARTD1 deficiencies von Ding, Xia, Chaudhuri, Arnab Ray, Callen, Elsa, Pang, Yan, Biswas, Kajal, Klarmann, Kimberly D., Martin, Betty K., Burkett, Sandra, Cleveland, Linda, Stauffer, Stacey, Sullivan, Teresa, Dewan, Aashish, Marks, Hanna, Tubbs, Anthony T., Wong, Nancy, Buehler, Eugen, Akagi, Keiko, Martin, Scott E., Keller, Jonathan R., Nussenzweig, André, Sharan, Shyam K.

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A germline mutation in SRRM2, a splicing factor gene, is implicated in papillary thyroid carcinoma predisposition von Tomsic, Jerneja, He, Huiling, Akagi, Keiko, Liyanarachchi, Sandya, Pan, Qun, Bertani, Blake, Nagy, Rebecca, Symer, David E., Blencowe, Benjamin J., Chapelle, Albert de la

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Mutations in U4atac snRNA, a Component of the Minor Spliceosome, in the Developmental Disorder MOPD I von He, Huiling, Liyanarachchi, Sandya, Akagi, Keiko, Nagy, Rebecca, Li, Jingfeng, Dietrich, Rosemary C., Li, Wei, Sebastian, Nikhil, Wen, Bernard, Xin, Baozhong, Singh, Jarnail, Yan, Pearlly, Alder, Hansjuerg, Haan, Eric, Wieczorek, Dagmar, Albrecht, Beate, Puffenberger, Erik, Wang, Heng, Westman, Judith A., Padgett, Richard A., Symer, David E., de la Chapelle, Albert

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Multiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513 in thyroid cancer von He, Huiling, Li, Wei, Liyanarachchi, Sandya, Srinivas, Mukund, Wang, Yanqiang, Akagi, Keiko, Wang, Yao, Wu, Dayong, Wang, Qianben, Jin, Victor, Symer, David E., Shen, Rulong, Phay, John, Nagy, Rebecca, de la Chapelle, Albert

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Merkel Cell Polyomavirus Exhibits Dominant Control of the Tumor Genome and Transcriptome in Virus-Associated Merkel Cell Carcinoma von Starrett, Gabriel J, Marcelus, Christina, Cantalupo, Paul G, Katz, Joshua P, Cheng, Jingwei, Akagi, Keiko, Thakuria, Manisha, Rabinowits, Guilherme, Wang, Linda C, Symer, David E, Pipas, James M, Harris, Reuben S, DeCaprio, James A

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Hematopoiesis and leukemogenesis in mice expressing oncogenic NrasG12D from the endogenous locus von Li, Qing, Haigis, Kevin M., McDaniel, Andrew, Harding-Theobald, Emily, Kogan, Scott C., Akagi, Keiko, Wong, Jasmine C.Y., Braun, Benjamin S., Wolff, Linda, Jacks, Tyler, Shannon, Kevin

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An antisense promoter in mouse L1 retrotransposon open reading frame-1 initiates expression of diverse fusion transcripts and limits retrotransposition von Li, Jingfeng, Kannan, Manoj, Trivett, Anna L, Liao, Hongling, Wu, Xiaolin, Akagi, Keiko, Symer, David E

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Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras von Coakley, Kristen M, Shannon, Kevin, Li, Qing, Warner, Kegan, Przybranowski, Sally, Akagi, Keiko, Krisman, Kimberly, Kogan, Scott C, Parada, Luis, Diaz-Flores, Ernesto, Gorman, Matthew, Roose, Jeroen P, Kim, Doris, Bonifas, Jeannette M, Crone, Michael, Jenkins, Nancy A, Wolff, Linda, Lauchle, Jennifer O, Copeland, Neal G, Sebolt-Leopold, Judith, Tran, Mary, Le, Doan T

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Mouse endogenous retroviruses can trigger premature transcriptional termination at a distance von Li, Jingfeng, Akagi, Keiko, Hu, Yongjun, Trivett, Anna L, Hlynialuk, Christopher J W, Swing, Deborah A, Volfovsky, Natalia, Morgan, Tamara C, Golubeva, Yelena, Stephens, Robert M, Smith, David E, Symer, David E

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Sleeping Beauty-Mediated Somatic Mutagenesis Implicates CSF1 in the Formation of High-Grade Astrocytomas von BENDER, Aaron M, COLLIER, Lara S, LARGAESPADA, David A, JENKINS, Robert B, RODRIGUEZ, Fausto J, TIEU, Christina, LARSON, Jon D, HALDER, Chandralekha, MAHLUM, Eric, KOLLMEYER, Thomas M, AKAGI, Keiko, SARKAR, Gobinda

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Identification of PDE4D as a Proliferation Promoting Factor in Prostate Cancer Using a Sleeping Beauty Transposon-Based Somatic Mutagenesis Screen von RAHRMANN, Eric P, COLLIER, Lara S, WEI HUANG, LARGAESPADA, David A, MARKER, Paul C, KNUTSON, Todd P, DOYAL, Meghan E, KUSLAK, Sheri L, GREEN, Laura E, MALINOWSKI, Rita L, ROETHE, Laura, AKAGI, Keiko, WAKNITZ, Michelle

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Recurrent retroviral vector integration at the Mds1/Evi1 locus in nonhuman primate hematopoietic cells von Calmels, Boris, Ferguson, Cole, Laukkanen, Mikko O., Adler, Rima, Faulhaber, Marion, Kim, Hyeoung-Joon, Sellers, Stephanie, Hematti, Peiman, Schmidt, Manfred, von Kalle, Christof, Akagi, Keiko, Donahue, Robert E., Dunbar, Cynthia E.

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Ultra-rare mutation in long-range enhancer predisposes to thyroid carcinoma with high penetrance von He, Huiling, Li, Wei, Wu, Dayong, Nagy, Rebecca, Liyanarachchi, Sandya, Akagi, Keiko, Jendrzejewski, Jaroslaw, Jiao, Hong, Hoag, Kevin, Wen, Bernard, Srinivas, Mukund, Waidyaratne, Gavisha, Wang, Rui, Wojcicka, Anna, Lattimer, Ilene R, Stachlewska, Elzbieta, Czetwertynska, Malgorzata, Dlugosinska, Joanna, Gierlikowski, Wojciech, Ploski, Rafal, Krawczyk, Marek, Jazdzewski, Krystian, Kere, Juha, Symer, David E, Jin, Victor, Wang, Qianben, de la Chapelle, Albert

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Murine leukemias with retroviral insertions at Lmo2 are predictive of the leukemias induced in SCID-X1 patients following retroviral gene therapy von Davé, Utpal P, Akagi, Keiko, Tripathi, Rati, Cleveland, Susan M, Thompson, Mary A, Yi, Ming, Stephens, Robert, Downing, James R, Jenkins, Nancy A, Copeland, Neal G

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Region-specific saturation germline mutagenesis in mice using the Sleeping Beauty transposon system von Takeda, Junji, Keng, Vincent W, Yae, Kojiro, Hayakawa, Tomoko, Mizuno, Sumi, Uno, Yoshihiro, Yusa, Kosuke, Kokubu, Chikara, Kinoshita, Taroh, Akagi, Keiko, Jenkins, Nancy A, Copeland, Neal G, Horie, Kyoji

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