A reversible phospho-switch mediated by ULK1 regulates the activity of autophagy protease ATG4B von Pengo, N., Agrotis, A., Prak, K., Jones, J., Ketteler, R.

Volltext

Redundancy of human ATG4 protease isoforms in autophagy and LC3/GABARAP processing revealed in cells von Agrotis, Alexander, Pengo, Niccolo, Burden, Jemima J., Ketteler, Robin

Volltext

Human ATG4 autophagy proteases counteract attachment of ubiquitin-like LC3/GABARAP proteins to other cellular proteins von Agrotis, Alexander, von Chamier, Lucas, Oliver, Harriet, Kiso, Koshiro, Singh, Tanya, Ketteler, Robin

Volltext

A new age in functional genomics using CRISPR/Cas9 in arrayed library screening von Agrotis, Alexander, Ketteler, Robin

Volltext

On ATG4B as Drug Target for Treatment of Solid Tumours-The Knowns and the Unknowns von Agrotis, Alexander, Ketteler, Robin

Volltext

Protective Role for Toll-Like Receptor-9 in the Development of Atherosclerosis in Apolipoprotein E–Deficient Mice von Koulis, Christine, Chen, Yung-Chih, Hausding, Christian, Ahrens, Ingo, Kyaw, Tin Soe, Tay, Christopher, Allen, Terri, Jandeleit-Dahm, Karin, Sweet, Matthew J, Akira, Shizuo, Bobik, Alexander, Peter, Karlheinz, Agrotis, Alex

Volltext

Understanding the role of transforming growth factor-β1 in intimal thickening after vascular injury von KHAN, R, AGROTIS, A, BOBIK, A

Volltext

Conventional B2 B cell depletion ameliorates whereas its adoptive transfer aggravates atherosclerosis von Kyaw, Tin, Tay, Christopher, Khan, Abdul, Dumouchel, Vanessa, Cao, Anh, To, Kelly, Kehry, Merilyn, Dunn, Robert, Agrotis, Alex, Tipping, Peter, Bobik, Alex, Toh, Ban-Hock

Volltext

A Novel Mouse Model of Atherosclerotic Plaque Instability for Drug Testing and Mechanistic/Therapeutic Discoveries Using Gene and MicroRNA Expression Profiling von Chen, Yung-Chih, Bui, Anh Viet, Diesch, Jeannine, Manasseh, Richard, Hausding, Christian, Rivera, Jennifer, Haviv, Izhak, Agrotis, Alex, Htun, Nay Min, Jowett, Jeremy, Hagemeyer, Christoph Eugen, Hannan, Ross D, Bobik, Alex, Peter, Karlheinz

Volltext

Actin remodelling controls proteasome homeostasis upon stress von Williams, Thomas David, Cacioppo, Roberta, Agrotis, Alexander, Black, Ailsa, Zhou, Houjiang, Rousseau, Adrien

Volltext

Foxp3+ Tregs are recruited to the retina to repair pathological angiogenesis von Deliyanti, Devy, Talia, Dean M., Zhu, Tong, Maxwell, Mhairi J., Agrotis, Alex, Jerome, Jack R., Hargreaves, Emily M., Gerondakis, Steven, Hibbs, Margaret L., Mackay, Fabienne, Wilkinson-Berka, Jennifer L.

Volltext

B1a B Lymphocytes Are Atheroprotective by Secreting Natural IgM That Increases IgM Deposits and Reduces Necrotic Cores in Atherosclerotic Lesions von Kyaw, Tin, Tay, Christopher, Krishnamurthi, Surendran, Kanellakis, Peter, Agrotis, Alex, Tipping, Peter, Bobik, Alex, Toh, Ban-Hock

Volltext

ATG5 is dispensable for ATG8ylation of cellular proteins von Ketteler, Robin, Kiso, Koshiro, von Chamier, Lucas, Agrotis, Alexander

Volltext

High-Mobility Group Box Protein 1 Neutralization Reduces Development of Diet-Induced Atherosclerosis in Apolipoprotein E–Deficient Mice von Kanellakis, Peter, Agrotis, Alex, Soe Kyaw, Tin, Koulis, Christine, Ahrens, Ingo, Mori, Shuji, Takahashi, Hideo K, Liu, Keyue, Peter, Karlheinz, Nishibori, Masahiro, Bobik, Alex

Volltext

Higher throughput drug screening for rare respiratory diseases: readthrough therapy in primary ciliary dyskinesia von Lee, Dani Do Hyang, Cardinale, Daniela, Nigro, Ersilia, Butler, Colin R, Rutman, Andrew, Fassad, Mahmoud R, Hirst, Robert A, Moulding, Dale, Agrotis, Alexander, Forsythe, Elisabeth, Peckham, Daniel, Robson, Evie, Smith, Claire M, Somavarapu, Satyanarayana, Beales, Philip L, Hart, Stephen L, Janes, Sam M, Mitchison, Hannah M, Ketteler, Robin, Hynds, Robert E, O'Callaghan, Christopher

Volltext

Cytokine Therapy With Interleukin-2/Anti-Interleukin-2 Monoclonal Antibody Complexes Expands CD4+CD25+Foxp3+ Regulatory T Cells and Attenuates Development and Progression of Athero... von TAM NGUYEN DINH, TIN SOE KYAW, KANELLAKIS, Peter, TO, Kelly, TIPPING, Peter, TOH, Ban-Hock, BOBIK, Alexander, AGROTIS, Alex

Volltext

Diagnostic performance of ADC and ADCratio in MRI-based prostate cancer assessment: A systematic review and meta-analysis von Agrotis, Georgios, Pooch, Eduardo, Abdelatty, Mohamed, Benson, Sean, Vassiou, Aikaterini, Vlychou, Marianna, Beets-Tan, Regina G. H., Schoots, Ivo G.

Volltext

Increased Expression of the DNA-Binding Cytokine HMGB1 in Human Atherosclerotic Lesions: Role of Activated Macrophages and Cytokines von Kalinina, N, Agrotis, A, Antropova, Y, DiVitto, G, Kanellakis, P, Kostolias, G, Ilyinskaya, O, Tararak, E, Bobik, A

Volltext

The cooperative IGS RT-GIMs: a reliable estimation of the global ionospheric electron content distribution in real time von Liu, Qi, Hernández-Pajares, Manuel, Yang, Heng, Monte-Moreno, Enric, Roma-Dollase, David, García-Rigo, Alberto, Li, Zishen, Wang, Ningbo, Laurichesse, Denis, Blot, Alexis, Zhao, Qile, Zhang, Qiang, Hauschild, André, Agrotis, Loukis, Schmitz, Martin, Wübbena, Gerhard, Stürze, Andrea, Krankowski, Andrzej, Schaer, Stefan, Feltens, Joachim, Komjathy, Attila, Ghoddousi-Fard, Reza

Volltext

Inhibition of the Nuclear Receptor RORγ and Interleukin-17A Suppresses Neovascular Retinopathy: Involvement of Immunocompetent Microglia von Talia, Dean M, Deliyanti, Devy, Agrotis, Alex, Wilkinson-Berka, Jennifer L

Volltext