ATR inhibition induces synthetic lethality and overcomes chemoresistance in TP53- or ATM-defective chronic lymphocytic leukemia cells von Kwok, Marwan, Davies, Nicholas, Agathanggelou, Angelo, Smith, Edward, Oldreive, Ceri, Petermann, Eva, Stewart, Grant, Brown, Jeff, Lau, Alan, Pratt, Guy, Parry, Helen, Taylor, Malcolm, Moss, Paul, Hillmen, Peter, Stankovic, Tatjana

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Role of the ras-association domain family 1 tumor suppressor gene in human cancers von AGATHANGGELOU, Angelo, COOPER, Wendy N, LATIF, Farida

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Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours von AGATHANGGELOU, Angelo, HONORIO, Sofia, HOSOE, Shigeto, LERMAN, Michael I, MINNA, John D, MAHER, Eamonn R, LATIF, Farida, MACARTNEY, Donia P, MARTINEZ, Alonso, DALLOL, Ashraf, RADER, Janet, FULLWOOD, Paul, CHAUHAN, Anita, WALKER, Rosemary, SHAW, Jacqueline A

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Dynamic changes in clonal cytogenetic architecture during progression of chronic lymphocytic leukemia in patients and patient-derived murine xenografts von Davies, Nicholas J, Kwok, Marwan, Gould, Clive, Oldreive, Ceri E, Mao, Jingwen, Parry, Helen, Smith, Edward, Agathanggelou, Angelo, Pratt, Guy, Taylor, Alexander Malcolm R, Moss, Paul, Griffiths, Mike, Stankovic, Tatjana

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Targeting the Ataxia Telangiectasia Mutated-null phenotype in chronic lymphocytic leukemia with pro-oxidants von Agathanggelou, Angelo, Weston, Victoria J, Perry, Tracey, Davies, Nicholas J, Skowronska, Anna, Payne, Daniel T, Fossey, John S, Oldreive, Ceri E, Wei, Wenbin, Pratt, Guy, Parry, Helen, Oscier, David, Coles, Steve J, Hole, Paul S, Darley, Richard L, McMahon, Michael, Hayes, John D, Moss, Paul, Stewart, Grant S, Taylor, A Malcolm R, Stankovic, Tatjana

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Involvement of the RASSF1A tumor suppressor gene in controlling cell migration von DALLOL, Ashraf, AGATHANGGELOU, Angelo, TOMMASI, Stella, PFEIFER, Gerd P, MAHER, Eamonn R, LATIF, Farida

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Synthetic lethality in chronic lymphocytic leukaemia with DNA damage response defects by targeting the ATR pathway von Kwok, Marwan, Dr, Davies, Nicholas, PhD, Agathanggelou, Angelo, PhD, Smith, Edward, BSc, Petermann, Eva, PhD, Yates, Eliot, BMedSc, Brown, Jeffrey, PhD, Lau, Alan, PhD, Stankovic, Tatjana, MD

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Detection of RASSF1A aberrant promoter hypermethylation in sputum from chronic smokers and ductal carcinoma in situ from breast cancer patients von HONORIO, Sofia, AGATHANGGELOU, Angelo, SCHUERMANN, Marcus, PANKOW, Wulf, VIACAVA, Paolo, MAHER, Eamonn R, LATIF, Farida

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Epigenetic inactivation of the candidate 3p21.3 suppressor gene BLU in human cancers von AGATHANGGELOU, Angelo, DALLOL, Ashraf, MAHER, Eamonn R, MINNA, John D, LATIF, Farida, ZÖCHBAUER-MÜLLER, Sabine, MORRISSEY, Catherine, HONORIO, Sofia, HESSON, Luke, MARTINSSON, Tommy, FONG, Kwun M, KUO, Michael J, PO WING YUEN

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Depletion of the Ras association domain family 1, isoform A-Associated novel microtubule-associated protein, C19ORF5/MAP1S, causes mitotic abnormalities von DALLOL, Ashraf, COOPER, Wendy N, M-MULLA, Fahd, AGATHANGGELOU, Angelo, MAHER, Eamonn R, LATIF, Farida

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T-cell number and subtype influence the disease course of primary chronic lymphocytic leukaemia xenografts in alymphoid mice von Oldreive, Ceri E, Skowronska, Anna, Davies, Nicholas J, Parry, Helen, Agathanggelou, Angelo, Krysov, Sergey, Packham, Graham, Rudzki, Zbigniew, Cronin, Laura, Vrzalikova, Katerina, Murray, Paul, Odintsova, Elena, Pratt, Guy, Taylor, A Malcolm R, Moss, Paul, Stankovic, Tatjana

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RASSF1A promoter region CpG island hypermethylation in phaeochromocytomas and neuroblastoma tumours von ASTUTI, Dewi, AGATHANGGELOU, Angelo, ENG, Charis, MAHER, Eamonn R, LATIF, Farida, HONORIO, Sofia, DALLOL, Ashraf, MARTINSSON, Tommy, KOGNER, Per, CUMMINS, Carole, NEUMANN, Hartmut P. H, VOUTILAINEN, Raimo, DAHIA, Patricia

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Targeting the p53 Pathway in CLL: State of the Art and Future Perspectives von Kwok, Marwan, Agathanggelou, Angelo, Davies, Nicholas, Stankovic, Tatjana

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CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions von Zimmermann, Michal, Murina, Olga, Reijns, Martin A. M., Agathanggelou, Angelo, Challis, Rachel, Tarnauskaitė, Žygimantė, Muir, Morwenna, Fluteau, Adeline, Aregger, Michael, McEwan, Andrea, Yuan, Wei, Clarke, Matthew, Lambros, Maryou B., Paneesha, Shankara, Moss, Paul, Chandrashekhar, Megha, Angers, Stephane, Moffat, Jason, Brunton, Valerie G., Hart, Traver, de Bono, Johann, Stankovic, Tatjana, Jackson, Andrew P., Durocher, Daniel

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Induction of a CD8+ T-cell response to the MAGE cancer testis antigen by combined treatment with azacitidine and sodium valproate in patients with acute myeloid leukemia and myelod... von Goodyear, Oliver, Agathanggelou, Angelo, Novitzky-Basso, Igor, Siddique, Shamyla, McSkeane, Tina, Ryan, Gordon, Vyas, Paresh, Cavenagh, Jamie, Stankovic, Tanja, Moss, Paul, Craddock, Charles

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Frequent epigenetic inactivation of the RASSF1A tumor suppressor gene in Hodgkin's lymphoma von MURRAY, Paul G, QIU, Guo-Hua, STARCZYNSKI, Jane, CROCKER, John, PARKES, Sheila E, AMBINDER, Richard F, YOUNG, Lawrence S, QIAN TAO, LI FU, WAITES, Elyse R, SRIVASTAVA, Gopesh, HEYS, Duncan, AGATHANGGELOU, Angelo, LATIF, Farida, GRUNDY, Richard G, MANN, Jillian R

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Correction: Kwok et al. Targeting the p53 Pathway in CLL: State of the Art and Future Perspectives. Cancers 2021, 13 , 4681 von Kwok, Marwan, Agathanggelou, Angelo, Davies, Nicholas, Stankovic, Tatjana

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Aniline-containing derivatives of parthenolide: Synthesis and anti-chronic lymphocytic leukaemia activity von Quy, Alex S., Li, Xingjian, Male, Louise, Stankovic, Tatjana, Agathanggelou, Angelo, Fossey, John S.

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TLR9 expression in chronic lymphocytic leukemia identifies a promigratory subpopulation and novel therapeutic target von Kennedy, Emma, Coulter, Eve, Halliwell, Emma, Profitos-Peleja, Nuria, Walsby, Elisabeth, Clark, Barnaby, Phillips, Elizabeth H., Burley, Thomas A., Mitchell, Simon, Devereux, Stephen, Fegan, Christopher D., Jones, Christopher I., Johnston, Rosalynd, Chevassut, Tim, Schulz, Ralph, Seiffert, Martina, Agathanggelou, Angelo, Oldreive, Ceri, Davies, Nicholas, Stankovic, Tatjana, Liloglou, Triantafillos, Pepper, Chris, Pepper, Andrea G.S.

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USP7 inhibition alters homologous recombination repair and targets CLL cells independently of ATM/p53 functional status von Agathanggelou, Angelo, Smith, Edward, Davies, Nicholas J., Kwok, Marwan, Zlatanou, Anastasia, Oldreive, Ceri E., Mao, Jingwen, Da Costa, David, Yadollahi, Sina, Perry, Tracey, Kearns, Pamela, Skowronska, Anna, Yates, Elliot, Parry, Helen, Hillmen, Peter, Reverdy, Celine, Delansorne, Remi, Paneesha, Shankara, Pratt, Guy, Moss, Paul, Taylor, A.Malcolm R., Stewart, Grant S., Stankovic, Tatjana

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