Predicting antibody binders and generating synthetic antibodies using deep learning von Lim, Yoong Wearn, Adler, Adam S, Johnson, David S

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An Integrated Genomic Screen Identifies LDHB as an Essential Gene for Triple-Negative Breast Cancer von MCCLELAND, Mark L, ADLER, Adam S, BELVIN, Marcia, HATZIVASSILIOU, Georgia, BLACKWOOD, Elizabeth M, CORSON, Laura, EVANGELISTA, Marie, JIPING ZHA, FIRESTEIN, Ron, YONGLEI SHANG, HUNSAKER, Thomas, TRUONG, Tom, PETERSON, David, TORRES, Eric, LI LI, HALEY, Benjamin, STEPHAN, Jean-Philippe

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Single-cell transcriptomics reveals the effect of PD-L1/TGF-β blockade on the tumor microenvironment von Lim, Yoong Wearn, Coles, Garry L, Sandhu, Savreet K, Johnson, David S, Adler, Adam S, Stone, Erica L

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Lactate Dehydrogenase B Is Required for the Growth of KRAS-Dependent Lung Adenocarcinomas von MCCLELAND, Mark L, ADLER, Adam S, JACKSON, Erica, FORREST, William F, FIRESTEIN, Ron, DEMING, Laura, COSINO, Ely, LEE, Leslie, BLACKWOOD, Elizabeth M, SOLON, Margaret, TAO, Janet, LI LI, SHAMES, David

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An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth von Adler, Adam S, McCleland, Mark L, Yee, Sharon, Yaylaoglu, Murat, Hussain, Sofia, Cosino, Ely, Quinones, Gabriel, Modrusan, Zora, Seshagiri, Somasekar, Torres, Eric, Chopra, Vivek S, Haley, Benjamin, Zhang, Zemin, Blackwood, Elizabeth M, Singh, Mallika, Junttila, Melissa, Stephan, Jean-Philippe, Liu, Jinfeng, Pau, Gregoire, Fearon, Eric R, Jiang, Zhaoshi, Firestein, Ron

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Sequencing the B Cell Receptor Repertoires of Antibody-Deficient Individuals With and Without Infection Susceptibility von Lim, Yoong Wearn, Ramirez, Neftali Jose, Asensio, Michael A., Chiang, Yao, Müller, Gabriele, Mrovecova, Pavla, Mitsuiki, Noriko, Krausz, Máté, Camacho-Ordonez, Nadezhda, Warnatz, Klaus, Adler, Adam S., Grimbacher, Bodo

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CDK8 maintains tumor dedifferentiation and embryonic stem cell pluripotency von Adler, Adam S, McCleland, Mark L, Truong, Tom, Lau, Shari, Modrusan, Zora, Soukup, Tim M, Roose-Girma, Merone, Blackwood, Elizabeth M, Firestein, Ron

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The histone demethylase UTX enables RB-dependent cell fate control von Wang, Jordon K, Tsai, Miao-Chih, Poulin, Gino, Adler, Adam S, Chen, Shuzhen, Liu, Helen, Shi, Yang, Chang, Howard Y

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Monoclonal antibody humanness score and its applications von Gao, Sean H, Huang, Kexin, Tu, Hua, Adler, Adam S

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Antibody repertoire analysis of mouse immunization protocols using microfluidics and molecular genomics von Asensio, Michael A, Lim, Yoong Wearn, Wayham, Nicholas, Stadtmiller, Kacy, Edgar, Robert C, Leong, Jackson, Leong, Renee, Mizrahi, Rena A, Adams, Matthew S, Simons, Jan Fredrik, Spindler, Matthew J, Johnson, David S, Adler, Adam S

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Genetic regulators of large-scale transcriptional signatures in cancer von Chang, Howard Y, Adler, Adam S, Lin, Meihong, Horlings, Hugo, Nuyten, Dimitry S A, van de Vijver, Marc J

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Affinity maturation of antibodies by combinatorial codon mutagenesis versus error-prone PCR von Simons, Jan Fredrik, Lim, Yoong Wearn, Carter, Kyle P, Wagner, Ellen K, Wayham, Nicholas, Adler, Adam S, Johnson, David S

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Global expression profiling in atopic eczema reveals reciprocal expression of inflammatory and lipid genes von Sääf, Annika M, Tengvall-Linder, Maria, Chang, Howard Y, Adler, Adam S, Wahlgren, Carl-Fredrik, Scheynius, Annika, Nordenskjöld, Magnus, Bradley, Maria

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The C2 Domain of the Rsp5 Ubiquitin Ligase Binds Membrane Phosphoinositides and Directs Ubiquitination of Endosomal Cargo von Dunn, Rebecca, Klos, Deborah A., Adler, Adam S., Hicke, Linda

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The transcription factor ZNF217 is a prognostic biomarker and therapeutic target during breast cancer progression von Littlepage, Laurie E, Adler, Adam S, Kouros-Mehr, Hosein, Huang, Guiqing, Chou, Jonathan, Krig, Sheryl R, Griffith, Obi L, Korkola, James E, Qu, Kun, Lawson, Devon A, Xue, Qing, Sternlicht, Mark D, Dijkgraaf, Gerrit J P, Yaswen, Paul, Rugo, Hope S, Sweeney, Colleen A, Collins, Colin C, Gray, Joe W, Chang, Howard Y, Werb, Zena

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A transcriptional program mediating entry into cellular quiescence von Liu, Helen, Adler, Adam S, Segal, Eran, Chang, Howard Y

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Systematic functional characterization of cis-regulatory motifs in human core promoters von Sinha, Saurabh, Adler, Adam S, Field, Yair, Chang, Howard Y, Segal, Eran

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MYC can induce DNA breaks in vivo and in vitro independent of reactive oxygen species von Ray, Suma, Atkuri, Kondala R, Deb-Basu, Debabrita, Adler, Adam S, Chang, Howard Y, Herzenberg, Leonore A, Felsher, Dean W

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CSN5 Isopeptidase Activity Links COP9 Signalosome Activation to Breast Cancer Progression von ADLER, Adam S, LITTLEPAGE, Laurie E, MEIHONG LIN, KAWAHARA, Tiara L. A, WONG, David J, WERB, Zena, CHANG, Howard Y

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GMP Manufacturing and IND-Enabling Studies of a Recombinant Hyperimmune Globulin Targeting SARS-CoV-2 von Mizrahi, Rena A, Lin, Wendy Y, Gras, Ashley, Niedecken, Ariel R, Wagner, Ellen K, Keating, Sheila M, Ikon, Nikita, Manickam, Vishal A, Asensio, Michael A, Leong, Jackson, Medina-Cucurella, Angelica V, Benzie, Emily, Carter, Kyle P, Chiang, Yao, Edgar, Robert C, Leong, Renee, Lim, Yoong Wearn, Simons, Jan Fredrik, Spindler, Matthew J, Stadtmiller, Kacy, Wayham, Nicholas, Büscher, Dirk, Terencio, Jose Vicente, Germanio, Clara Di, Chamow, Steven M, Olson, Charles, Pino, Paula A, Park, Jun-Gyu, Hicks, Amberlee, Ye, Chengjin, Garcia-Vilanova, Andreu, Martinez-Sobrido, Luis, Torrelles, Jordi B, Johnson, David S, Adler, Adam S

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