Rapamycin extends murine lifespan but has limited effects on aging von Neff, Frauke, Flores-Dominguez, Diana, Ryan, Devon P, Horsch, Marion, Schröder, Susanne, Adler, Thure, Afonso, Luciana Caminha, Aguilar-Pimentel, Juan Antonio, Becker, Lore, Garrett, Lillian, Hans, Wolfgang, Hettich, Moritz M, Holtmeier, Richard, Hölter, Sabine M, Moreth, Kristin, Prehn, Cornelia, Puk, Oliver, Rácz, Ildikó, Rathkolb, Birgit, Rozman, Jan, Naton, Beatrix, Ordemann, Rainer, Adamski, Jerzy, Beckers, Johannes, Bekeredjian, Raffi, Busch, Dirk H, Ehninger, Gerhard, Graw, Jochen, Höfler, Heinz, Klingenspor, Martin, Klopstock, Thomas, Ollert, Markus, Stypmann, Jörg, Wolf, Eckhard, Wurst, Wolfgang, Zimmer, Andreas, Fuchs, Helmut, Gailus-Durner, Valérie, Hrabe de Angelis, Martin, Ehninger, Dan

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Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice von Xie, Kan, Ryan, Devon P., Pearson, Brandon L., Henzel, Kristin S., Neff, Frauke, Vidal, Ramon O., Hennion, Magali, Lehmann, Isabelle, Schleif, Melvin, Schröder, Susanne, Adler, Thure, Rathkolb, Birgit, Rozman, Jan, Schütz, Anna-Lena, Prehn, Cornelia, Mickael, Michel E., Weiergräber, Marco, Adamski, Jerzy, Busch, Dirk H., Ehninger, Gerhard, Matynia, Anna, Jackson, Walker S., Wolf, Eckhard, Fuchs, Helmut, Gailus-Durner, Valerie, Bonn, Stefan, de Angelis, Martin Hrabě, Ehninger, Dan

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Increased estrogen to androgen ratio enhances immunoglobulin levels and impairs B cell function in male mice von Aguilar-Pimentel, Juan Antonio, Cho, Yi-Li, Gerlini, Raffaele, Calzada-Wack, Julia, Wimmer, Maria, Mayer-Kuckuk, Philipp, Adler, Thure, Schmidt-Weber, Carsten B., Busch, Dirk H., Fuchs, Helmut, Gailus-Durner, Valérie, Ollert, Markus, Hrabě de Angelis, Martin, Ohlsson, Claes, Poutanen, Matti, Teperino, Raffaele, Strauss, Leena

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Early pulmonary response is critical for extra-pulmonary carbon nanoparticle mediated effects: comparison of inhalation versus intra-arterial infusion exposures in mice von Ganguly, Koustav, Ettehadieh, Dariusch, Upadhyay, Swapna, Takenaka, Shinji, Adler, Thure, Karg, Erwin, Krombach, Fritz, Kreyling, Wolfgang G, Schulz, Holger, Schmid, Otmar, Stoeger, Tobias

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Expression Pattern of G Protein-Coupled Receptor 30 in LacZ Reporter Mice von Isensee, Jörg, Meoli, Luca, Zazzu, Valeria, Nabzdyk, Christoph, Witt, Henning, Soewarto, Dian, Effertz, Karin, Fuchs, Helmut, Gailus-Durner, Valérie, Busch, Dirk, Adler, Thure, de Angelis, Martin Hrabé, Irgang, Markus, Otto, Christiane, Noppinger, Patricia Ruiz

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A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes von Kollmus, Heike, Fuchs, Helmut, Lengger, Christoph, Haselimashhadi, Hamed, Bogue, Molly A., Östereicher, Manuela A., Horsch, Marion, Adler, Thure, Aguilar-Pimentel, Juan Antonio, Amarie, Oana Veronica, Becker, Lore, Beckers, Johannes, Calzada-Wack, Julia, Garrett, Lillian, Hans, Wolfgang, Hölter, Sabine M., Klein-Rodewald, Tanja, Maier, Holger, Mayer-Kuckuk, Philipp, Miller, Gregor, Moreth, Kristin, Neff, Frauke, Rathkolb, Birgit, Rácz, Ildikó, Rozman, Jan, Spielmann, Nadine, Treise, Irina, Busch, Dirk, Graw, Jochen, Klopstock, Thomas, Wolf, Eckhard, Wurst, Wolfgang, Yildirim, Ali Önder, Mason, Jeremy, Torres, Arturo, Balling, Rudi, Mehaan, Terry, Gailus-Durner, Valerie, Schughart, Klaus, Hrabě de Angelis, Martin

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The Role of Fibroblast Growth Factor-Binding Protein 1 in Skin Carcinogenesis and Inflammation von Schmidt, Marcel Oliver, Garman, Khalid Ammar, Lee, Yong Gu, Zuo, Chong, Beck, Patrick James, Tan, Mingjun, Aguilar-Pimentel, Juan Antonio, Ollert, Markus, Schmidt-Weber, Carsten, Fuchs, Helmut, Gailus-Durner, Valerie, Hrabe de Angelis, Martin, Becker, Lore, Vernaleken, Alexandra, Klopstock, Thomas, Adler, Thure, Treise, Irina, Horsch, Marion, Moreth, Kristin, Brommage, Robert, Hans, Wolfgang, Östereicher, Manuela, Steinkamp, Ralph, Lengger, Christoph, Maier, Holger, Stoeger, Claudia, Leuchtenberger, Stefanie, Busch, Dirk H., Beckers, Johannes, Bekeredjian, Raffi, Garrett, Lillian, Hölter, Sabine M., Zimprich, Annemarie, Amarie, Oana, Wurst, Wolfgang, Graw, Jochen, Rozman, Jan, Calzada-Wack, Julia, da Silva-Buttkus, Patricia, Neff, Frauke, Klingenspor, Martin, Racz, Ildiko, Zimmer, Andreas, Rathkolb, Birgit, Wolf, Eckhard, Tassi, Elena, Riegel, Anna Tate, Wellstein, Anton

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Requirement of the RNA-editing Enzyme ADAR2 for Normal Physiology in Mice von Horsch, Marion, Seeburg, Peter H., Adler, Thure, Aguilar-Pimentel, Juan Antonio, Becker, Lore, Calzada-Wack, Julia, Garrett, Lilian, Götz, Alexander, Hans, Wolfgang, Higuchi, Miyoko, Hölter, Sabine M., Naton, Beatrix, Prehn, Cornelia, Puk, Oliver, Rácz, Ildikó, Rathkolb, Birgit, Rozman, Jan, Schrewe, Anja, Adamski, Jerzy, Busch, Dirk H., Esposito, Irene, Graw, Jochen, Ivandic, Boris, Klingenspor, Martin, Klopstock, Thomas, Mempel, Martin, Ollert, Markus, Schulz, Holger, Wolf, Eckhard, Wurst, Wolfgang, Zimmer, Andreas, Gailus-Durner, Valérie, Fuchs, Helmut, de Angelis, Martin Hrabě, Beckers, Johannes

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Defective immuno- and thymoproteasome assembly causes severe immunodeficiency von Treise, Irina, Huber, Eva M., Klein-Rodewald, Tanja, Heinemeyer, Wolfgang, Grassmann, Simon A., Basler, Michael, Adler, Thure, Rathkolb, Birgit, Helming, Laura, Andres, Christian, Klaften, Matthias, Landbrecht, Christina, Wieland, Thomas, Strom, Tim M., McCoy, Kathy D., Macpherson, Andrew J., Wolf, Eckhard, Groettrup, Marcus, Ollert, Markus, Neff, Frauke, Gailus-Durner, Valerie, Fuchs, Helmut, Hrabě de Angelis, Martin, Groll, Michael, Busch, Dirk H.

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Large-scale phenotyping of an accurate genetic mouse model of JNCL identifies novel early pathology outside the central nervous system von Staropoli, John F, Haliw, Larissa, Biswas, Sunita, Garrett, Lillian, Hölter, Sabine M, Becker, Lore, Skosyrski, Sergej, Da Silva-Buttkus, Patricia, Calzada-Wack, Julia, Neff, Frauke, Rathkolb, Birgit, Rozman, Jan, Schrewe, Anja, Adler, Thure, Puk, Oliver, Sun, Minxuan, Favor, Jack, Racz, Ildikó, Bekeredjian, Raffi, Busch, Dirk H, Graw, Jochen, Klingenspor, Martin, Klopstock, Thomas, Wolf, Eckhard, Wurst, Wolfgang, Zimmer, Andreas, Lopez, Edith, Harati, Hayat, Hill, Eric, Krause, Daniela S, Guide, Jolene, Dragileva, Ella, Gale, Evan, Wheeler, Vanessa C, Boustany, Rose-Mary, Brown, Diane E, Breton, Sylvie, Ruether, Klaus, Gailus-Durner, Valérie, Fuchs, Helmut, de Angelis, Martin Hrabě, Cotman, Susan L

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CIP2A Promotes T-Cell Activation and Immune Response to Listeria monocytogenes Infection von Côme, Christophe, Cvrljevic, Anna, Khan, Mohd Moin, Treise, Irina, Adler, Thure, Aguilar-Pimentel, Juan Antonio, Au-Yeung, Byron, Sittig, Eleonora, Laajala, Teemu Daniel, Chen, Yiling, Oeder, Sebastian, Calzada-Wack, Julia, Horsch, Marion, Aittokallio, Tero, Busch, Dirk H, Ollert, Markus W, Neff, Frauke, Beckers, Johannes, Gailus-Durner, Valerie, Fuchs, Helmut, Hrabě de Angelis, Martin, Chen, Zhi, Lahesmaa, Riitta, Westermarck, Jukka

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High Mobility Group N Proteins Modulate the Fidelity of the Cellular Transcriptional Profile in a Tissue- and Variant-specific Manner von Kugler, Jamie E., Horsch, Marion, Huang, Di, Furusawa, Takashi, Rochman, Mark, Garrett, Lillian, Becker, Lore, Bohla, Alexander, Hölter, Sabine M., Prehn, Cornelia, Rathkolb, Birgit, Racz, Ildikó, Aguilar-Pimentel, Juan Antonio, Adler, Thure, Adamski, Jerzy, Beckers, Johannes, Busch, Dirk H., Eickelberg, Oliver, Klopstock, Thomas, Ollert, Markus, Stöger, Tobias, Wolf, Eckhard, Wurst, Wolfgang, Yildirim, Ali Önder, Zimmer, Andreas, Gailus-Durner, Valérie, Fuchs, Helmut, Hrabě de Angelis, Martin, Garfinkel, Benny, Orly, Joseph, Ovcharenko, Ivan, Bustin, Michael

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Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression von Kaklamanos, Aimilios, Rozman, Jan, Roulis, Manolis, Karagianni, Niki, Armaka, Maria, Wu, Moya, Brachthäuser, Laura, Calzada-Wack, Julia, Horsch, Marion, Beckers, Johannes, Rathkolb, Birgit, Adler, Thure, Neff, Frauke, Wolf, Eckhard, Gailus-Durner, Valerie, Fuchs, Helmut, de Angelis, Martin Hrabe, Kollias, George

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Pleiotropic functions for transcription factor zscan10 von Kraus, Petra, V, Sivakamasundari, Yu, Hong Bing, Xing, Xing, Lim, Siew Lan, Adler, Thure, Pimentel, Juan Antonio Aguilar, Becker, Lore, Bohla, Alexander, Garrett, Lillian, Hans, Wolfgang, Hölter, Sabine M, Janas, Eva, Moreth, Kristin, Prehn, Cornelia, Puk, Oliver, Rathkolb, Birgit, Rozman, Jan, Adamski, Jerzy, Bekeredjian, Raffi, Busch, Dirk H, Graw, Jochen, Klingenspor, Martin, Klopstock, Thomas, Neff, Frauke, Ollert, Markus, Stoeger, Tobias, Yildrim, Ali Önder, Eickelberg, Oliver, Wolf, Eckhard, Wurst, Wolfgang, Fuchs, Helmut, Gailus-Durner, Valérie, de Angelis, Martin Hrabě, Lufkin, Thomas, Stanton, Lawrence W

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New C3H Kit N824K/WT cancer mouse model develops late-onset malignant mammary tumors with high penetrance von Klein-Rodewald, Tanja, Micklich, Kateryna, Sanz-Moreno, Adrián, Tost, Monica, Calzada-Wack, Julia, Adler, Thure, Klaften, Matthias, Sabrautzki, Sibylle, Aigner, Bernhard, Kraiger, Markus, Gailus-Durner, Valerie, Fuchs, Helmut, Gründer, Albert, Pahl, Heike, Wolf, Eckhard, Hrabe de Angelis, Martin, Rathkolb, Birgit

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Generation and Standardized, Systemic Phenotypic Analysis of Pou3f3L423P Mutant Mice von Kumar, Sudhir, Rathkolb, Birgit, Kemter, Elisabeth, Sabrautzki, Sibylle, Michel, Dian, Adler, Thure, Becker, Lore, Beckers, Johannes, Busch, Dirk H, Garrett, Lillian, Hans, Wolfgang, Hölter, Sabine M, Horsch, Marion, Klingenspor, Martin, Klopstock, Thomas, Rácz, Ildikó, Rozman, Jan, Vargas Panesso, Ingrid Liliana, Vernaleken, Alexandra, Zimmer, Andreas, Fuchs, Helmut, Gailus-Durner, Valérie, Hrabě de Angelis, Martin, Wolf, Eckhard, Aigner, Bernhard

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The endocytic adaptor Eps15 controls marginal zone B cell numbers von Pozzi, Benedetta, Amodio, Stefania, Lucano, Caterina, Sciullo, Anna, Ronzoni, Simona, Castelletti, Daniela, Adler, Thure, Treise, Irina, Betsholtz, Ingrid Holmberg, Rathkolb, Birgit, Busch, Dirk H, Wolf, Eckhard, Fuchs, Helmut, Gailus-Durner, Valérie, de Angelis, Martin Hrabě, Betsholtz, Christer, Casola, Stefano, Di Fiore, Pier Paolo, Offenhäuser, Nina

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In vivo functional requirement of the mouse Ifitm1 gene for germ cell development, interferon mediated immune response and somitogenesis von Klymiuk, Ingeborg, Kenner, Lukas, Adler, Thure, Busch, Dirk H, Boersma, Auke, Irmler, Martin, Fridrich, Barbara, Gailus-Durner, Valérie, Fuchs, Helmut, Leitner, Nicole, Müller, Mathias, Kühn, Ralf, Schlederer, Michaela, Treise, Irina, de Angelis, Martin Hrabě, Beckers, Johannes

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Immune modulation by Fas ligand reverse signaling: lymphocyte proliferation is attenuated by the intracellular Fas ligand domain von Lückerath, Katharina, Kirkin, Vladimir, Melzer, Inga Maria, Thalheimer, Frederic B., Siele, Dagmar, Milani, Wiebke, Adler, Thure, Aguilar-Pimentel, Antonio, Horsch, Marion, Michel, Geert, Beckers, Johannes, Busch, Dirk H., Ollert, Markus, Gailus-Durner, Valerie, Fuchs, Helmut, Hrabĕ de Angelis, Martin, Staal, Frank J.T., Rajalingam, Krishnaraj, Hueber, Anne-Odile, Strobl, Lothar J., Zimber-Strobl, Ursula, Zörnig, Martin

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Correction of Bleeding Symptoms in von Willebrand Factor–Deficient Mice by Liver-Expressed von Willebrand Factor Mutants von Marx, Isabelle, Lenting, Peter J, Adler, Thure, Pendu, Ronan, Christophe, Olivier D, Denis, Cécile V

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