PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 3: Comparative assessement of prediction methods of human clearance von Ring, Barbara J., Chien, Jenny Y., Adkison, Kimberly K., Jones, Hannah M., Rowland, Malcolm, Jones, Rhys Do, Yates, James W.T., Ku, M. Sherry, Gibson, Christopher R., He, Handan, Vuppugalla, Ragini, Marathe, Punit, Fischer, Volker, Dutta, Sandeep, Sinha, Vikash K., Björnsson, Thorir, Lavé, Thierry, Poulin, Patrick

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PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: Prediction of plasma concentration–time profiles in human by using the physiologically‐based pharmaco... von Poulin, Patrick, Jones, Rhys D.O., Jones, Hannah M., Gibson, Christopher R., Rowland, Malcolm, Chien, Jenny Y., Ring, Barbara J., Adkison, Kimberly K., Ku, M. Sherry, He, Handan, Vuppugalla, Ragini, Marathe, Punit, Fischer, Volker, Dutta, Sandeep, Sinha, Vikash K., Björnsson, Thorir, Lavé, Thierry, Yates, James W.T.

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PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 4: Prediction of plasma concentration–time profiles in human from in vivo preclinical data by using the... von Vuppugalla, Ragini, Marathe, Punit, He, Handan, Jones, Rhys D.O., Yates, James W.T., Jones, Hannah M., Gibson, Christopher R., Chien, Jenny Y., Ring, Barbara J., Adkison, Kimberly K., Ku, M. Sherry, Fischer, Volker, Dutta, Sandeep, Sinha, Vikash K., Björnsson, Thorir, Lavé, Thierry, Poulin, Patrick

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Oral Sulfasalazine as a Clinical BCRP Probe Substrate: Pharmacokinetic Effects of Genetic Variation (C421A) and Pantoprazole Coadministration von Adkison, Kimberly K., Vaidya, Soniya S., Lee, Daniel Y., Koo, Seok Hwee, Li, Linghui, Mehta, Amar A., Gross, Annette S., Polli, Joseph W., Humphreys, Joan E., Lou, Yu, Lee, Edmund J.D.

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Pharmacokinetic and pharmacokinetic/pharmacodynamic characterization of the dolutegravir/rilpivirine two‐drug regimen in SWORD‐1/‐2 phase 3 studies von Mehta, Rashmi, Lagishetty, Chakradhar V., Angelis, Konstantinos, Aylott, Alicia, Kahl, Lesley, Blair, Libby, Matthews, Jessica, Wynne, Brian, Crauwels, Herta, Underwood, Mark, Adkison, Kimberly K.

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Principles and applicability of CSF sampling for the assessment of CNS drug delivery and pharmacodynamics von Shen, Danny D., Artru, Alan A., Adkison, Kimberly K.

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PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 2: Comparative assessment of prediction methods of human volume of distribution von Jones, Rhys Do, Jones, Hannah M., Rowland, Malcolm, Gibson, Christopher R., Yates, James W.T., Chien, Jenny Y., Ring, Barbara J., Adkison, Kimberly K., Ku, M. Sherry, He, Handan, Vuppugalla, Ragini, Marathe, Punit, Fischer, Volker, Dutta, Sandeep, Sinha, Vikash K., Björnsson, Thorir, Lavé, Thierry, Poulin, Patrick

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Pharmacokinetics and Short-Term Safety of 873140, a Novel CCR5 Antagonist, in Healthy Adult Subjects von Adkison, Kimberly K, Shachoy-Clark, Anne, Fang, Lei, Lou, Yu, O'Mara, Kathy, Berrey, M. Michelle, Piscitelli, Stephen C

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PhRMA CPCDC Initiative on Predictive Models of Human Pharmacokinetics, Part 1: Goals, Properties of the Phrma Dataset, and Comparison with Literature Datasets von Poulin, Patrick, Jones, Hannah M., Jones, Rhys Do, Yates, James W.T., Gibson, Christopher R., Chien, Jenny Y., Ring, Barbara J., Adkison, Kimberly K., He, Handan, Vuppugalla, Ragini, Marathe, Punit, Fischer, Volker, Dutta, Sandeep, Sinha, Vikash K., Björnsson, Thorir, Lavé, Thierry, Sherry Ku, M.

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Pharmacokinetics of hepatitis C virus NS5A inhibitor JNJ-56914845 (GSK2336805) in subjects with hepatic impairment von Adkison, Kimberly K., Gan, Jianjun, Elko-Simms, Lucinda, Gardner, Stephen, Dumont, Etienne, Jones, Lori S., Saunders, Joanne, Marbury, Thomas, Smith, William, Berg, Jolene, Galloway, Christopher, Stump, Patrick J.

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The ABCG2 C421A polymorphism does not affect oral nitrofurantoin pharmacokinetics in healthy Chinese male subjects von Adkison, Kimberly K., Vaidya, Soniya S., Lee, Daniel Y., Koo, Seok Hwee, Li, Linghui, Mehta, Amar A., Gross, Annette S., Polli, Joseph W., Lou, Yu, Lee, Edmund J. D.

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Effects of omeprazole and ritonavir on absorption and elimination of the hepatitis C virus NS5A inhibitor GSK2336805 in healthy adults von Adkison, Kimberly K., Jones, Lori S., Lou, Yu, Gan, Jianjun, Wilfret, David A.

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Synthesis and evaluation of potent and selective β3 adrenergic receptor agonists containing heterobiaryl carboxylic acids von Shearer, Barry G., Chao, Esther Y., Uehling, David E., Deaton, David N., Cowan, Conrad, Sherman, Bryan W., Milliken, Tula, Faison, Walter, Brown, Kathleen, Adkison, Kimberly K., Lee, Frank

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In Vitro and Clinical Investigation of the Relationship Between CCR5 Receptor Occupancy and Anti-HIV Activity of Aplaviroc von Demarest, James F., Sparks, Sara S., Schell, Kathleen, Shibayama, Shiro, McDanal, Charlene B., Fang, Lei, Adkison, Kimberly K., Shachoy-Clark, Anne, Piscitelli, Stephen C.

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Steady-State Brain Concentrations of Antihistamines in Rats von Doan, Kelly Mahar, Wring, Stephen A., Shampine, Larry J., Jordan, Kelly H., Bishop, James P., Kratz, John, Yang, Eric, Serabjit-Singh, Cosette J., Adkison, Kimberly K., Polli, Joseph W.

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Evaluation of the Drug Interaction Potential of Aplaviroc, a Novel Human Immunodeficiency Virus Entry Inhibitor, Using a Modified Cooperstown 5 + 1 Cocktail von Johnson, Brendan M., Song, Ivy H., Adkison, Kimberly K., Borland, Julie, Fang, Lei, Lou, Yu, Berrey, M. Michelle, Nafziger, Anne N., Piscitelli, Stephen C., Bertino Jr, Joseph S.

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Steady-state brain concentrations of antihistamines in rats: interplay of membrane permeability, P-glycoprotein efflux and plasma protein binding von Mahar Doan, Kelly M, Wring, Stephen A, Shampine, Larry J, Jordan, Kelly H, Bishop, James P, Kratz, John, Yang, Eric, Serabjit-Singh, Cosette J, Adkison, Kimberly K, Polli, Joseph W

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The effects of ritonavir and lopinavir/ritonavir on the pharmacokinetics of a novel CCR5 antagonist, aplaviroc, in healthy subjects von Adkison, Kimberly K., Shachoy‐Clark, Anne, Fang, Lei, Lou, Yu, Otto, Vicky R., Berrey, M. Michelle, Piscitelli, Stephen C.

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Monitoring liver safety in drug development: The GSK experience von Hunt, Christine M., Papay, Julie I., Edwards, Rita I., Theodore, Dickens, Alpers, David H., Dollery, Colin, DeBruin, Tjerk W., Adkison, Kimberly K., Stirnadel, Heide A., Gibbs, Trevor G.

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Cassette dosing: rapid in vivo assessment of pharmacokinetics von Frick, Lloyd W, Adkison, Kimberly K, Wells-Knecht, Kevin J, Woollard, Patrick, Higton, David M

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