RTX proteins: a highly diverse family secreted by a common mechanism von Linhartová, Irena, Bumba, Ladislav, Mašín, Jiří, Basler, Marek, Osička, Radim, Kamanová, Jana, Procházková, Kateřina, Adkins, Irena, Hejnová-Holubová, Jana, Sadílková, Lenka, Morová, Jana, Šebo, Peter

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Physical modalities inducing immunogenic tumor cell death for cancer immunotherapy von Adkins, Irena, Fucikova, Jitka, Garg, Abhishek D, Agostinis, Patrizia, Špíšek, Radek

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High hydrostatic pressure in cancer immunotherapy and biomedicine von Adkins, Irena, Hradilova, Nada, Palata, Ondrej, Sadilkova, Lenka, Palova-Jelinkova, Lenka, Spisek, Radek

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Invasion of Dendritic Cells, Macrophages and Neutrophils by the Bordetella Adenylate Cyclase Toxin: A Subversive Move to Fool Host Immunity von Fedele, Giorgio, Schiavoni, Ilaria, Adkins, Irena, Klimova, Nela, Sebo, Peter

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Myeloid - derived suppressor cells in Type 1 diabetes are an expanded population exhibiting diverse T-cell suppressor mechanisms von Grohová, Anna, Dáňová, Klára, Adkins, Irena, Šumník, Zdeněk, Petruželková, Lenka, Obermannová, Barbora, Koloušková, Stanislava, Špíšek, Radek, Palová-Jelínková, Lenka

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Severe, but not mild heat-shock treatment induces immunogenic cell death in cancer cells von Adkins, Irena, Sadilkova, Lenka, Hradilova, Nada, Tomala, Jakub, Kovar, Marek, Spisek, Radek

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Generation of dendritic cell-based vaccine using high hydrostatic pressure for non-small cell lung cancer immunotherapy von Hradilova, Nada, Sadilkova, Lenka, Palata, Ondrej, Mysikova, Dagmar, Mrazkova, Hana, Lischke, Robert, Spisek, Radek, Adkins, Irena

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SOT101 induces NK cell cytotoxicity and potentiates antibody-dependent cell cytotoxicity and anti-tumor activity von Antosova, Zuzana, Podzimkova, Nada, Tomala, Jakub, Augustynkova, Katerina, Sajnerova, Katerina, Nedvedova, Eva, Sirova, Milada, de Martynoff, Guy, Bechard, David, Moebius, Ulrich, Kovar, Marek, Spisek, Radek, Adkins, Irena

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Radiotherapy in Combination With Cytokine Treatment von Palata, Ondrej, Hradilova Podzimkova, Nada, Nedvedova, Eva, Umprecht, Alexandra, Sadilkova, Lenka, Palova Jelinkova, Lenka, Spisek, Radek, Adkins, Irena

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815 Combination with IL-15Rβγ superagonist, Nanrilkefusp alfa, enhances CAR T and BOXR T cell anti-tumor activity von Kuiper, Emily, Whiteman, Kathleen, Garafola, Daniel, Koirala, Pratirodh, Smith, Shannon, Danova, Klara, Simonova, Ekaterina, Jelinkova, Lenka Palova, Adkins, Irena, Jensen-Smith, Amy

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713 Nanrilkefusp alfa, a high-affinity IL-15Rβγ agonist, promotes an innate and adaptive anti-tumour inflammatory environment as single agent or combined with anti-PD-1 in patients... von Danek, Petr, Simonova, Ekaterina, Podzimkova, Nada, Bechard, David, Sachse, Richard, Kiemle-Kallee, Joachim, Moebius, Ulrich, Spisek, Radek, Adkins, Irena, Steegmaier, Martin, Jelinkova, Lenka Palova

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Calcium influx rescues adenylate cyclase-hemolysin from rapid cell membrane removal and enables phagocyte permeabilization by toxin pores von Fiser, Radovan, Masin, Jiri, Bumba, Ladislav, Pospisilova, Eva, Fayolle, Catherine, Basler, Marek, Sadilkova, Lenka, Adkins, Irena, Kamanova, Jana, Cerny, Jan, Konopasek, Ivo, Osicka, Radim, Leclerc, Claude, Sebo, Peter

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Bordetella adenylate cyclase toxin differentially modulates toll-like receptor-stimulated activation, migration and T cell stimulatory capacity of dendritic cells von Adkins, Irena, Kamanova, Jana, Kocourkova, Aneta, Svedova, Martina, Tomala, Jakub, Janova, Hana, Masin, Jiri, Chladkova, Barbora, Bumba, Ladislav, Kovar, Marek, Ross, Padraig J, Tuckova, Ludmila, Spisek, Radek, Mills, Kingston H G, Sebo, Peter

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1087 SOT201 is a novel cis-acting immunocytokine targeting IL-15Rβγ to reinvigorate PD-1+tumor infiltrating lymphocytes and potentiate anti-tumor efficacy von Adkins, Irena, Antosova, Zuzana, Behalova, Katerina, Danek, Petr, Danova, Klara, Fabisik, Matej, Hladikova, Kamila, Kalynovska, Nataliia, Kosinova, Lucie, Marasek, Pavel, Mazhara, Vladyslav, Podzimkova, Nada, Praslicka, Jan, Sajnerova, Katerina, Sirova, Milada, Bechard, David, Moebius, Ulrich, Kovar, Marek, Jelinkova, Lenka Palova, Spisek, Radek, Steegmaier, Martin

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563 Pharmacodynamics and pharmacokinetics of SO-C101 in cynomolgus monkeys von Podzimkova, Nada, Adkins, Irena, Martynoff, Guy de, Bechard, David, Spisek, Radek, Moebius, Ulrich

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High hydrostatic pressure affects antigenic pool in tumor cells: Implication for dendritic cell-based cancer immunotherapy von Urbanova, Linda, Hradilova, Nada, Moserova, Irena, Vosahlikova, Sarka, Sadilkova, Lenka, Hensler, Michal, Spisek, Radek, Adkins, Irena

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Abstract 6686: SO-C101 displays strong anti-tumor effect in TC-1 and TRAMP-C2 tumor mice and in combination with PD-1 blockade prevents tumor development in a NK and CD8+ T cells d... von Adkins, Irena, Mikyskova, Romana, Hradilova, Nada, de Martynoff, Guy, Bechard, David, Moebius, Ulrich, Reinis, Milan, Spisek, Radek

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Cyclic AMP-Elevating Capacity of Adenylate Cyclase Toxin-Hemolysin Is Sufficient for Lung Infection but Not for Full Virulence of Bordetella pertussis von Skopova, Karolina, Tomalova, Barbora, Kanchev, Ivan, Rossmann, Pavel, Svedova, Martina, Adkins, Irena, Bibova, Ilona, Tomala, Jakub, Masin, Jiri, Guiso, Nicole, Osicka, Radim, Sedlacek, Radislav, Kovar, Marek, Sebo, Peter

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Interim safety and efficacy results from AURELIO-03: A phase 1 dose escalation study of the IL-2/IL-15 receptor βγ superagonist SOT101 as a single agent and in combination with pem... von Garralda, Elena, Naing, Aung, Galvao, Vladimir, LoRusso, Patricia, Grell, Peter, Cassier, Philippe Alexandre, Gomez-Roca, Carlos A., Korakis, Iphigenie, Bechard, David, Palova Jelinkova, Lenka, Adkins, Irena, Tillmanns, Sascha, Kiemle-Kallee, Joachim, Marabelle, Aurelien, Champiat, Stephane

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Detection of tumor antigens and tumor-antigen specific T cells in NSCLC patients: Correlation of the quality of T cell responses with NSCLC subtype von Palata, Ondrej, Podzimkova Hradilova, Nada, Mysiková, Dagmar, Kutna, Beata, Mrazkova, Hana, Lischke, Robert, Spisek, Radek, Adkins, Irena

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