Influence of Affinity and Antigen Internalization on the Uptake and Penetration of Anti-HER2 Antibodies in Solid Tumors von RUDNICK, Stephen I, JIANLONG LOU, SHALLER, Calvin C, YONG TANG, KLEIN-SZANTO, Andres J. P, WEINER, Louis M, MARKS, James D, ADAMS, Gregory P

Volltext

Impact of intrinsic affinity on functional binding and biological activity of EGFR antibodies von Zhou, Yu, Goenaga, Anne-Laure, Harms, Brian D, Zou, Hao, Lou, Jianlong, Conrad, Fraser, Adams, Gregory P, Schoeberl, Birgit, Nielsen, Ulrik B, Marks, James D

Volltext

Broadening of neutralization activity to directly block a dominant antibody-driven SARS-coronavirus evolution pathway von Sui, Jianhua, Aird, Daniel R, Tamin, Azaibi, Murakami, Akikazu, Yan, Meiying, Yammanuru, Anuradha, Jing, Huaiqi, Kan, Biao, Liu, Xin, Zhu, Quan, Yuan, Qing-An, Adams, Gregory P, Bellini, William J, Xu, Jianguo, Anderson, Larry J, Marasco, Wayne A

Volltext

DeBouganin Diabody Fusion Protein Overcomes Drug Resistance to ADCs Comprised of Anti-Microtubule Agents von Chooniedass, Shilpa, Dillon, Rachelle L, Premsukh, Arjune, Hudson, Peter J, Adams, Gregory P, MacDonald, Glen C, Cizeau, Jeannick

Volltext

Monoclonal antibody therapy of cancer von Weiner, Louis M, Adams, Gregory P

Volltext

Monoclonal Antibody Therapy for Cancer von Mehren, Margaret von, Adams, Gregory P, Weiner, Louis M

Volltext

Targeting C4-demethylating genes in the cholesterol pathway sensitizes cancer cells to EGF receptor inhibitors via increased EGF receptor degradation von Sukhanova, Anna, Gorin, Andrey, Serebriiskii, Ilya G, Gabitova, Linara, Zheng, Hui, Restifo, Diana, Egleston, Brian L, Cunningham, David, Bagnyukova, Tetyana, Liu, Hanqing, Nikonova, Anna, Adams, Gregory P, Zhou, Yan, Yang, Dong-Hua, Mehra, Ranee, Burtness, Barbara, Cai, Kathy Q, Klein-Szanto, Andres, Kratz, Lisa E, Kelley, Richard I, Weiner, Louis M, Herman, Gail E, Golemis, Erica A, Astsaturov, Igor

Volltext

Anti-CD70 immunocytokines for exploitation of interferon-γ-induced RIP1-dependent necrosis in renal cell carcinoma von Chen, Peirong, Nogusa, Shoko, Thapa, Roshan J, Shaller, Calvin, Simmons, Heidi, Peri, Suraj, Adams, Gregory P, Balachandran, Siddharth

Volltext

Avidity-Mediated Enhancement of In vivo Tumor Targeting by Single-Chain Fv Dimers von ADAMS, Gregory P, TAI, Mei-Sheng, MCCARTNEY, John E, MARKS, James D, STAFFORD, Walter F, HOUSTON, L. L, HUSTON, James S, WEINER, Louis M

Volltext

Effective Treatment of Established Human Breast Tumor Xenografts in Immunodeficient Mice with a Single Dose of the α-Emitting Radioisotope Astatine-211 Conjugated to Anti-HER2/neu... von ROBINSON, Matthew K, SHALLER, Calvin, GARMESTANI, Kayhan, PLASCJAK, Paul S, HODGE, Kathryn M, YUAN, Qing-An, MARKS, James D, WALDMANN, Thomas A, BRECHBIE, Martin W, ADAMS, Gregory P

Volltext

Cellular studies of binding, internalization and retention of a radiolabeled EGFR-binding affibody molecule von Nordberg, Erika, Friedman, Mikaela, Göstring, Lovisa, Adams, Gregory P, Brismar, Hjalmar, Nilsson, Fredrik Y, Ståhl, Stefan, Glimelius, Bengt, Carlsson, Jörgen

Volltext

Ultrasmall Folate Receptor Alpha Targeted Enzymatically Cleavable Silica Nanoparticle Drug Conjugates Augment Penetration and Therapeutic Efficacy in Models of Cancer von Wu, Fei, Chen, Pei-Ming, Gardinier, Thomas C., Turker, Melik Z., Venkatesan, Aranapakam M., Patel, Vaibhav, Khor, Tin, Bradbury, Michelle S., Wiesner, Ulrich B., Adams, Gregory P., Germano, Geno, Chen, Feng, Ma, Kai

Volltext

Affinity and avidity in antibody-based tumor targeting von Rudnick, Stephen I, Adams, Gregory P

Volltext

CAR T Cells Targeting MISIIR for the Treatment of Ovarian Cancer and Other Gynecologic Malignancies von Rodriguez-Garcia, Alba, Sharma, Prannda, Poussin, Mathilde, Boesteanu, Alina C., Minutolo, Nicholas G., Gitto, Sarah B., Omran, Dalia K., Robinson, Matthew K., Adams, Gregory P., Simpkins, Fiona, Powell, Daniel J.

Volltext

Interferon-γ-induced necrosis: an antitumor biotherapeutic perspective von Balachandran, Siddharth, Adams, Gregory P

Volltext

A single treatment of yttrium-90-labeled CHX-A-c6.5 diabody inhibits the growth of established human tumor xenografts in immunodeficient mice von ADAMS, Gregory P, SHALLER, Calvin C, DADACHOVA, Ekaterina, SIMMONS, Heidi H, HORAK, Eva M, TESFAYE, Abohawariat, KLEIN-SZANTO, Andres J. P, MARKS, James D, BRECHBIEL, Martin W, WEINER, Louis M

Volltext

A rapid method to regenerate piezoelectric microcantilever sensors (PEMS) von Loo, LiNa, Wu, Wei, Shih, Wan Y, Shih, Wei-Heng, Borghaei, Hossein, Pourrezaei, Kambiz, Adams, Gregory P

Volltext

T Cell Activation by Antibody-Like Immunoreceptors: Increase in Affinity of the Single-Chain Fragment Domain above Threshold Does Not Increase T Cell Activation against Antigen-Pos... von Chmielewski, Markus, Hombach, Andreas, Heuser, Claudia, Adams, Gregory P, Abken, Hinrich

Volltext

Impact of Single-chain Fv Antibody Fragment Affinity on Nanoparticle Targeting of Epidermal Growth Factor Receptor-expressing Tumor Cells von Zhou, Yu, Drummond, Daryl C., Zou, Hao, Hayes, Mark E., Adams, Gregory P., Kirpotin, Dmitri B., Marks, James D.

Volltext

Expression of single-chain Fv-Fc fusions in Pichia pastoris von Powers, David B., Amersdorfer, Peter, Poul, Marie-Alix, Nielsen, Ulrik B., Shalaby, M.Refaat, Adams, Gregory P., Weiner, Louis M., Marks, James D.

Volltext