Early identification of promiscuous attributes of aldose reductase inhibitors using a DMSO-perturbation assay von Tomohara, Keisuke, Hasegawa, Naoto, Adachi, Isao, Horino, Yoshikazu, Nose, Takeru

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Direct chemical derivatization of natural plant extract: straightforward synthesis of natural plant-like hydantoin von Tomohara, Keisuke, Ito, Tomohiro, Hasegawa, Naoto, Kato, Atsushi, Adachi, Isao

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Protective Effects of Dietary Chamomile Tea on Diabetic Complications von Kato, Atsushi, Minoshima, Yuka, Yamamoto, Jo, Adachi, Isao, Watson, Alison A, Nash, Robert J

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Multivalency To Inhibit and Discriminate Hexosaminidases von Alvarez‐Dorta, Dimitri, King, Dustin T., Legigan, Thibaut, Ide, Daisuke, Adachi, Isao, Deniaud, David, Désiré, Jérôme, Kato, Atsushi, Vocadlo, David, Gouin, Sébastien G., Blériot, Yves

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Strategy for Designing Selective Lysosomal Acid α-Glucosidase Inhibitors: Binding Orientation and Influence on Selectivity von Kato, Atsushi, Nakagome, Izumi, Hata, Mizuki, Nash, Robert J, Fleet, George W J, Natori, Yoshihiro, Yoshimura, Yuichi, Adachi, Isao, Hirono, Shuichi

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Docking study and biological evaluation of pyrrolidine-based iminosugars as pharmacological chaperones for Gaucher disease von Kato, Atsushi, Nakagome, Izumi, Sato, Kasumi, Yamamoto, Arisa, Adachi, Isao, Nash, Robert J, Fleet, George W. J, Natori, Yoshihiro, Watanabe, Yasuka, Imahori, Tatsushi, Yoshimura, Yuichi, Takahata, Hiroki, Hirono, Shuichi

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Design of a New α-1- C -Alkyl-DAB Derivative Acting as a Pharmacological Chaperone for β-Glucocerebrosidase Using Ligand Docking and Molecular Dynamics Simulation von Nakagome, Izumi, Kato, Atsushi, Yamaotsu, Noriyuki, Yoshida, Tomoki, Ozawa, Shin-Ichiro, Adachi, Isao, Hirono, Shuichi

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Laboratory and practical synthesis of Suvorexant, a selective dual orexin receptor antagonist von Minehira, Daisuke, Takahara, Satoyuki, Adachi, Isao, Toyooka, Naoki

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Ginnalin B induces differentiation markers and modulates the proliferation/differentiation balance via the upregulation of NOTCH1 in human epidermal keratinocytes von Kato, Atsushi, Koyama, Junna, Shinzawa, Kenta, Imaeda, Shuki, Adachi, Isao, Nash, Robert J., Fleet, George W.J., Shintani, Megumi, Takeuchi, Chihiro, Ishikawa, Fumihiro

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Interpreting the behavior of concentration–response curves of hyaluronidase inhibitors under DMSO-perturbed assay conditions von Tomohara, Keisuke, Ito, Tomohiro, Onikata, Saika, Furusawa, Kota, Kato, Atsushi, Adachi, Isao

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3‑Fluoroazetidinecarboxylic Acids and trans,trans-3,4-Difluoroproline as Peptide Scaffolds: Inhibition of Pancreatic Cancer Cell Growth by a Fluoroazetidine Iminosugar von Liu, Zilei, Jenkinson, Sarah F, Vermaas, Tom, Adachi, Isao, Wormald, Mark R, Hata, Yukako, Kurashima, Yukiko, Kaji, Akira, Yu, Chu-Yi, Kato, Atsushi, Fleet, George W. J

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Hepatitis E virus outbreak in monkey facility, Japan von Yamamoto, Hiroshi, Suzuki, Juri, Matsuda, Atsushi, Ishida, Takafumi, Ami, Yasushi, Suzaki, Yuriko, Adachi, Isao, Wakita, Takaji, Takeda, Naokazu, Li, Tian-Cheng

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Looking-Glass Synergistic Pharmacological Chaperones: DGJ and L-DGJ from the Enantiomers of Tagatose von Jenkinson, Sarah F, Fleet, George W. J, Nash, Robert J, Koike, Yuriko, Adachi, Isao, Yoshihara, Akihide, Morimoto, Kenji, Izumori, Ken, Kato, Atsushi

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Synthesis of 1,2-trans-2-Acetamido-2-deoxyhomoiminosugars von Blériot, Yves, Tran, Anh Tuan, Prencipe, Giuseppe, Jagadeesh, Yerri, Auberger, Nicolas, Zhu, Sha, Gauthier, Charles, Zhang, Yongmin, Désiré, Jérôme, Adachi, Isao, Kato, Atsushi, Sollogoub, Matthieu

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Fluorinated and Conformationally Fixed Derivatives of l‑HomoDMDP: Synthesis and Glycosidase Inhibition von Li, Yi-Xian, Shimada, Yousuke, Adachi, Isao, Kato, Atsushi, Jia, Yue-Mei, Fleet, George W. J, Xiao, Min, Yu, Chu-Yi

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Protective Effects of Dietary 1,5-Anhydro‑d‑glucitol as a Blood Glucose Regulator in Diabetes and Metabolic Syndrome von Kato, Atsushi, Kunimatsu, Takahito, Yamashita, Yukiko, Adachi, Isao, Takeshita, Kei, Ishikawa, Fumihiro

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Iteamine, the first alkaloid isolated from Itea virginica L. inflorescence von Ayers, Benjamin J., Hollinshead, Jacqueline, Saville, Alexander W., Nakagawa, Shinpei, Adachi, Isao, Kato, Atsushi, Izumori, Ken, Bartholomew, Barbara, Fleet, George W.J., Nash, Robert J.

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Synthesis of new tricyclic thiolactams as potent antitumor agent for pancreatic cancer von Okada, Takuya, Minehira, Daisuke, Takada, Minetatsu, Urata, Hirokazu, Kato, Atsushi, Adachi, Isao, Kurashima, Yukiko, Kaji, Satoshi, Ogura, Tsutomu, Chiba, Shigeki, Esumi, Hiroyasu, Toyooka, Naoki

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Glycosidase Inhibition by All 10 Stereoisomeric 2,5-Dideoxy-2,5-iminohexitols Prepared from the Enantiomers of Glucuronolactone von Ayers, Benjamin J, Ngo, Nigel, Jenkinson, Sarah F, Martínez, R. Fernando, Shimada, Yousuke, Adachi, Isao, Weymouth-Wilson, Alexander C, Kato, Atsushi, Fleet, George W. J

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Inhibition of P-glycoprotein-mediated transport by terpenoids contained in herbal medicines and natural products von Yoshida, Naoko, Koizumi, Mariya, Adachi, Isao, Kawakami, Junichi

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