Transmission and spreading of tauopathy in transgenic mouse brain von Crowther, R. Anthony, Clavaguera, Florence, Abramowski, Dorothee, Goedert, Michel, Bolmont, Tristan, Probst, Alphonse, Tolnay, Markus, Fraser, Graham, Staufenbiel, Matthias, Stalder, Anna K, Jucker, Mathias, Beibel, Martin, Frank, Stephan

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Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease von Busche, Marc Aurel, Eichhoff, Gerhard, Adelsberger, Helmuth, Abramowski, Dorothee, Wiederhold, Karl-Heinz, Haass, Christian, Staufenbiel, Matthias, Konnerth, Arthur, Garaschuk, Olga

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CRISPR Screens Provide a Comprehensive Assessment of Cancer Vulnerabilities but Generate False-Positive Hits for Highly Amplified Genomic Regions von Munoz, Diana M, Cassiani, Pamela J, Li, Li, Billy, Eric, Korn, Joshua M, Jones, Michael D, Golji, Javad, Ruddy, David A, Yu, Kristine, McAllister, Gregory, DeWeck, Antoine, Abramowski, Dorothee, Wan, Jessica, Shirley, Matthew D, Neshat, Sarah Y, Rakiec, Daniel, de Beaumont, Rosalie, Weber, Odile, Kauffmann, Audrey, McDonald, 3rd, E Robert, Keen, Nicholas, Hofmann, Francesco, Sellers, William R, Schmelzle, Tobias, Stegmeier, Frank, Schlabach, Michael R

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The dual orexin receptor antagonist almorexant induces sleep and decreases orexin-induced locomotion by blocking orexin 2 receptors von Mang, Géraldine M, Dürst, Thomas, Bürki, Hugo, Imobersteg, Stefan, Abramowski, Dorothee, Schuepbach, Edi, Hoyer, Daniel, Fendt, Markus, Gee, Christine E

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Dietary Cu Stabilizes Brain Superoxide Dismutase 1 Activity and Reduces Amyloid Aβ Production in APP23 Transgenic Mice von Bayer, Thomas A., Schäfer, Stephanie, Simons, Andreas, Kemmling, André, Kamer, Thomas, Tepest, Ralf, Eckert, Anne, Schüssel, Katrin, Eikenberg, Oliver, Sturchler-Pierrat, Christine, Abramowski, Dorothee, Staufenbiel, Matthias, Multhaup, Gerd

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Symptomatic effect of donepezil, rivastigmine, galantamine and memantine on cognitive deficits in the APP23 model von VAN DAM, Debby, ABRAMOWSKI, Dorothee, STAUFENBIEL, Matthias, DE DEYN, Peter Paul

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Mutant huntingtin gene-dose impacts on aggregate deposition, DARPP32 expression and neuroinflammation in HdhQ150 mice von Young, Douglas, Mayer, Franziska, Vidotto, Nella, Schweizer, Tatjana, Berth, Ramon, Abramowski, Dorothee, Shimshek, Derya R, van der Putten, P Herman, Schmid, Peter

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Two Amyloid Precursor Protein Transgenic Mouse Models with Alzheimer Disease-Like Pathology von Sturchler-Pierrat, Christine, Abramowski, Dorothee, Duke, Mairead, Wiederhold, Karl-Heinz, Mistl, Claudia, Rothacher, Sabin, Ledermann, Brigit, Bürki, Kurt, Frey, Peter, Paganetti, Paolo A., Waridel, Caroline, Calhoun, Michael E., Jucker, Mathias, Probst, Alphonse, Staufenbiel, Matthias, Sommer, Bernd

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Neuronal Overexpression of Mutant Amyloid Precursor Protein Results in Prominent Deposition of Cerebrovascular Amyloid von Calhoun, Michael E., Burgermeister, Patrick, Phinney, Amie L., Stalder, Martina, Tolnay, Markus, Wiederhold, Karl-Heinz, Abramowski, Dorothee, Sturchler-Pierrat, Christine, Sommer, Bernd, Staufenbiel, Matthias, Jucker, Mathias

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Transgenic expression of β1 antibody in brain neurons impairs age-dependent amyloid deposition in APP23 mice von Paganetti, Paolo, Reichwald, Julia, Bleckmann, Dorothee, Abramowski, Dorothee, Ammaturo, Domenico, Barske, Carmen, Danner, Simone, Molinari, Maurizio, Müller, Matthias, Papin, Stéphanie, Rabe, Sabine, Schmid, Peter, Staufenbiel, Matthias

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Profile of cholesterol-related sterols in aged amyloid precursor protein transgenic mouse brain von Lütjohann, Dieter, Brzezinka, Andreas, Barth, Esther, Abramowski, Dorothee, Staufenbiel, Matthias, von Bergmann, Klaus, Beyreuther, Konrad, Multhaup, Gerd, Bayer, Thomas A

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Fragments of HdhQ150 mutant huntingtin form a soluble oligomer pool that declines with aggregate deposition upon aging von Marcellin, David, Abramowski, Dorothee, Young, Douglas, Richter, Jens, Weiss, Andreas, Marcel, Audrey, Maassen, Julia, Kauffmann, Muriel, Bibel, Miriam, Shimshek, Derya R, Faull, Richard L M, Bates, Gillian P, Kuhn, Rainer R, Van der Putten, P Herman, Schmid, Peter, Lotz, Gregor P

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Noninvasive Magnetic Resonance Imaging Detection of Cerebral Amyloid Angiopathy-Related Microvascular Alterations Using Superparamagnetic Iron Oxide Particles in APP Transgenic Mou... von Beckmann, Nicolau, Gérard, Christelle, Abramowski, Dorothée, Cannet, Catherine, Staufenbiel, Matthias

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Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening von McDonald, E. Robert, de Weck, Antoine, Schlabach, Michael R., Billy, Eric, Mavrakis, Konstantinos J., Hoffman, Gregory R., Belur, Dhiren, Castelletti, Deborah, Frias, Elizabeth, Gampa, Kalyani, Golji, Javad, Kao, Iris, Li, Li, Megel, Philippe, Perkins, Thomas A., Ramadan, Nadire, Ruddy, David A., Silver, Serena J., Sovath, Sosathya, Stump, Mark, Weber, Odile, Widmer, Roland, Yu, Jianjun, Yu, Kristine, Yue, Yingzi, Abramowski, Dorothee, Ackley, Elizabeth, Barrett, Rosemary, Berger, Joel, Bernard, Julie L., Billig, Rebecca, Brachmann, Saskia M., Buxton, Frank, Caothien, Roger, Caushi, Justina X., Chung, Franklin S., Cortés-Cros, Marta, deBeaumont, Rosalie S., Delaunay, Clara, Desplat, Aurore, Duong, William, Dwoske, Donald A., Eldridge, Richard S., Farsidjani, Ali, Feng, Fei, Feng, JiaJia, Flemming, Daisy, Forrester, William, Galli, Giorgio G., Gao, Zhenhai, Gauter, François, Gibaja, Veronica, Haas, Kristy, Hattenberger, Marc, Hood, Tami, Hurov, Kristen E., Jagani, Zainab, Jenal, Mathias, Johnson, Jennifer A., Jones, Michael D., Kapoor, Avnish, Korn, Joshua, Liu, Jilin, Liu, Qiumei, Liu, Shumei, Liu, Yue, Loo, Alice T., Macchi, Kaitlin J., Martin, Typhaine, McAllister, Gregory, Meyer, Amandine, Mollé, Sandra, Pagliarini, Raymond A., Phadke, Tanushree, Repko, Brian, Schouwey, Tanja, Shanahan, Frances, Shen, Qiong, Stamm, Christelle, Stephan, Christine, Stucke, Volker M., Tiedt, Ralph, Varadarajan, Malini, Venkatesan, Kavitha, Vitari, Alberto C., Wallroth, Marco, Weiler, Jan, Zhang, Jing, Mickanin, Craig, Myer, Vic E., Porter, Jeffery A., Lai, Albert, Bitter, Hans, Lees, Emma, Keen, Nicholas, Kauffmann, Audrey, Stegmeier, Frank, Hofmann, Francesco, Schmelzle, Tobias, Sellers, William R.

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Single-step detection of mutant huntingtin in animal and human tissues: A bioassay for Huntington’s disease von Weiss, Andreas, Abramowski, Dorothée, Bibel, Miriam, Bodner, Ruth, Chopra, Vanita, DiFiglia, Marian, Fox, Jonathan, Kegel, Kimberly, Klein, Corinna, Grueninger, Stephan, Hersch, Steven, Housman, David, Régulier, Etienne, Rosas, H. Diana, Stefani, Muriel, Zeitlin, Scott, Bilbe, Graeme, Paganetti, Paolo

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Exogenous Induction of Cerebral β-Amyloidogenesis Is Governed by Agent and Host von Meyer-Luehmann, Melanie, Coomaraswamy, Janaky, Bolmont, Tristan, Kaeser, Stephan, Schaefer, Claudia, Kilger, Ellen, Neuenschwander, Anton, Abramowski, Dorothee, Frey, Peter, Jaton, Anneliese L, Vigouret, Jean-Marie, Paganetti, Paolo, Walsh, Dominic M, Mathews, Paul M, Ghiso, Jorge, Staufenbiel, Matthias, Walker, Lary C, Jucker, Mathias

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The Discovery of SWI/SNF Chromatin Remodeling Activity as a Novel and Targetable Dependency in Uveal Melanoma von Rago, Florencia, Elliott, GiNell, Li, Ailing, Sprouffske, Kathleen, Kerr, Grainne, Desplat, Aurore, Abramowski, Dorothee, Chen, Julie T., Farsidjani, Ali, Xiang, Kay X., Bushold, Geoffrey, Feng, Yun, Shirley, Matthew D., Bric, Anka, Vattay, Anthony, Moebitz, Henrik, Nakajima, Katsumasa, Adair, Christopher D., Mathieu, Simon, Ntaganda, Rukundo, Smith, Troy, Papillon, Julien P. N., Kauffmann, Audrey, Ruddy, David A., Bhang, Hyo-eun C., Castelletti, Deborah, Jagani, Zainab

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Dispersible amyloid β-protein oligomers, protofibrils, and fibrils represent diffusible but not soluble aggregates: their role in neurodegeneration in amyloid precursor protein (AP... von Rijal Upadhaya, Ajeet, Capetillo-Zarate, Estibaliz, Kosterin, Irina, Abramowski, Dorothee, Kumar, Sathish, Yamaguchi, Haruyasu, Walter, Jochen, Fändrich, Marcus, Staufenbiel, Matthias, Thal, Dietmar Rudolf

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Aβ is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis von Jucker, Mathias, Herzig, Martin C, Winkler, David T, Burgermeister, Patrick, Pfeifer, Michelle, Kohler, Esther, Schmidt, Stephen D, Danner, Simone, Abramowski, Dorothee, Stürchler-Pierrat, Christine, Bürki, Kurt, van Duinen, Sjoerd G, Maat-Schieman, Marion L C, Staufenbiel, Matthias, Mathews, Paul M

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Early-onset axonal pathology in a novel P301S-Tau transgenic mouse model of frontotemporal lobar degeneration von van Eersel, Janet, Stevens, Claire H., Przybyla, Magdalena, Gladbach, Amadeus, Stefanoska, Kristie, Chan, Chesed Kai-Xin, Ong, Wei-Yi, Hodges, John R., Sutherland, Greg T., Kril, Jillian J., Abramowski, Dorothee, Staufenbiel, Matthias, Halliday, Glenda M., Ittner, Lars M.

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