Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ) von Degtjarik, Oksana, Golovenko, Dmitrij, Diskin-Posner, Yael, Abrahmsén, Lars, Rozenberg, Haim, Shakked, Zippora

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Inhibiting the system xC−/glutathione axis selectively targets cancers with mutant-p53 accumulation von Liu, David S., Duong, Cuong P., Haupt, Sue, Montgomery, Karen G., House, Colin M., Azar, Walid J., Pearson, Helen B., Fisher, Oliver M., Read, Matthew, Guerra, Glen R., Haupt, Ygal, Cullinane, Carleen, Wiman, Klas G., Abrahmsen, Lars, Phillips, Wayne A., Clemons, Nicholas J.

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Structural basis for high-affinity HER2 receptor binding by an engineered protein von Eigenbrot, Charles, Ultsch, Mark, Dubnovitsky, Anatoly, Abrahmsén, Lars, Härd, Torleif, Bax, Adriaan

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Extending Half-life by Indirect Targeting of the Neonatal Fc Receptor (FcRn) Using a Minimal Albumin Binding Domain von Andersen, Jan Terje, Pehrson, Rikard, Tolmachev, Vladimir, Daba, Muluneh Bekele, Abrahmsén, Lars, Ekblad, Caroline

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Targeting of Mutant p53 and the Cellular Redox Balance by APR-246 as a Strategy for Efficient Cancer Therapy von Bykov, Vladimir J N, Zhang, Qiang, Zhang, Meiqiongzi, Ceder, Sophia, Abrahmsen, Lars, Wiman, Klas G

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A thiol‐bound drug reservoir enhances APR‐246‐induced mutant p53 tumor cell death von Ceder, Sophia, Eriksson, Sofi E, Cheteh, Emarndeena H, Dawar, Swati, Corrales Benitez, Mariana, Bykov, Vladimir J N, Fujihara, Kenji M, Grandin, Mélodie, Li, Xiaodun, Ramm, Susanne, Behrenbruch, Corina, Simpson, Kaylene J, Hollande, Frédéric, Abrahmsen, Lars, Clemons, Nicholas J, Wiman, Klas G

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Engineering of a femtomolar affinity binding protein to human serum albumin von Jonsson, Andreas, Dogan, Jakob, Herne, Nina, Abrahmsén, Lars, Nygren, Per-Åke

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HEHEHE-Tagged Affibody Molecule May Be Purified by IMAC, Is Conveniently Labeled with [99mTc(CO)3]+, and Shows Improved Biodistribution with Reduced Hepatic Radioactivity Accumulat... von Tolmachev, Vladimir, Hofström, Camilla, Malmberg, Jennie, Ahlgren, Sara, Hosseinimehr, Seyed Jalal, Sandström, Mattias, Abrahmsén, Lars, Orlova, Anna, Gräslund, Torbjörn

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Design of an Optimized Scaffold for Affibody Molecules von Feldwisch, Joachim, Tolmachev, Vladimir, Lendel, Christofer, Herne, Nina, Sjöberg, Anna, Larsson, Barbro, Rosik, Daniel, Lindqvist, Eva, Fant, Gunilla, Höidén-Guthenberg, Ingmarie, Galli, Joakim, Jonasson, Per, Abrahmsén, Lars

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Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells von Ceder, Sophia, Eriksson, Sofi E., Liang, Ying Yu, Cheteh, Emarndeena H., Zhang, Si Min, Fujihara, Kenji M., Bianchi, Julie, Bykov, Vladimir J. N., Abrahmsen, Lars, Clemons, Nicholas J., Nordlund, Pär, Rudd, Sean G., Wiman, Klas G.

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Targeting of HER2 -Expressing Tumors Using 111 In-ABY-025, a Second-Generation Affibody Molecule with a Fundamentally Reengineered Scaffold von Ahlgren, Sara, Orlova, Anna, Wållberg, Helena, Hansson, Monika, Sandström, Mattias, Lewsley, Richard, Wennborg, Anders, Abrahmsén, Lars, Tolmachev, Vladimir, Feldwisch, Joachim

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Correction: Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells von Ceder, Sophia, Eriksson, Sofi E., Liang, Ying Yu, Cheteh, Emarndeena H., Zhang, Si Min, Fujihara, Kenji M., Bianchi, Julie, Bykov, Vladimir J. N., Abrahmsen, Lars, Clemons, Nicholas J., Nordlund, Pär, Rudd, Sean G., Wiman, Klas G.

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Affibody molecules: potential for in vivo imaging of molecular targets for cancer therapy von Tolmachev, Vladimir, Orlova, Anna, Nilsson, Fredrik Y, Feldwisch, Joachim, Wennborg, Anders, Abrahmsén, Lars

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High-affinity binding to staphylococcal protein A by an engineered dimeric Affibody molecule von Lindborg, Malin, Dubnovitsky, Anatoly, Olesen, Kenneth, Björkman, Tomas, Abrahmsén, Lars, Feldwisch, Joachim, Härd, Torleif

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Early Implementation of QbD in Biopharmaceutical Development: A Practical Example von Abrahmsén, Lars, Höidén-Guthenberg, Ingmarie, Ekblad, Caroline, Michael, Rebecca, Gallagher, Thomas R. A., Gómez de la Cuesta, Ramón, Smith, Noel, Obrezanova, Olga, Arnell, Andreas, Zurdo, Jesús, Stallwood, Yvette

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A GLP-1 receptor agonist conjugated to an albumin-binding domain for extended half-life von Lindgren, Joel, Refai, Essam, Zaitsev, Sergei V., Abrahmsén, Lars, Berggren, Per-Olof, Karlström, Amelie Eriksson

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Picropodophyllin causes mitotic arrest and catastrophe by depolymerizing microtubules via insulin-like growth factor-1 receptor-independent mechanism von Waraky, Ahmed, Akopyan, Karen, Parrow, Vendela, Strömberg, Thomas, Axelson, Magnus, Abrahmsén, Lars, Lindqvist, Arne, Larsson, Olle, Aleem, Eiman

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A Native Chemical Ligation Approach for Combinatorial Assembly of Affibody Molecules von Lindgren, Joel, Ekblad, Caroline, Abrahmsén, Lars, Eriksson Karlström, Amelie

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Synthetic affibody molecules : A novel class of affinity ligands for molecular imaging of HER2-expressing malignant tumors von ORLOVA, Anna, TOLMACHEV, Vladimir, PEHRSON, Rikard, LINDBORG, Malin, TRAN, Thuy, SANDSTRÖM, Mattias, NILSSON, Fredrik Y, WENNBORG, Anders, ABRAHMSEN, Lars, FELDWISCH, Joachim

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Evaluation of a Maleimido Derivative of CHX-A′′ DTPA for Site-Specific Labeling of Affibody Molecules von Tolmachev, Vladimir, Xu, Heng, Wållberg, Helena, Ahlgren, Sara, Hjertman, Magnus, Sjöberg, Anna, Sandström, Mattias, Abrahmsén, Lars, Brechbiel, Martin W, Orlova, Anna

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