Super-Enhancers in the Control of Cell Identity and Disease von Hnisz, Denes, Abraham, Brian J., Lee, Tong Ihn, Lau, Ashley, Saint-André, Violaine, Sigova, Alla A., Hoke, Heather A., Young, Richard A.

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Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes von Whyte, Warren A., Orlando, David A., Hnisz, Denes, Abraham, Brian J., Lin, Charles Y., Kagey, Michael H., Rahl, Peter B., Lee, Tong Ihn, Young, Richard A.

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Convergence of Developmental and Oncogenic Signaling Pathways at Transcriptional Super-Enhancers von Hnisz, Denes, Schuijers, Jurian, Lin, Charles Y., Weintraub, Abraham S., Abraham, Brian J., Lee, Tong Ihn, Bradner, James E., Young, Richard A.

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Control of Cell Identity Genes Occurs in Insulated Neighborhoods in Mammalian Chromosomes von Dowen, Jill M., Fan, Zi Peng, Hnisz, Denes, Ren, Gang, Abraham, Brian J., Zhang, Lyndon N., Weintraub, Abraham S., Schuijers, Jurian, Lee, Tong Ihn, Zhao, Keji, Young, Richard A.

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YY1 Is a Structural Regulator of Enhancer-Promoter Loops von Weintraub, Abraham S., Li, Charles H., Zamudio, Alicia V., Sigova, Alla A., Hannett, Nancy M., Day, Daniel S., Abraham, Brian J., Cohen, Malkiel A., Nabet, Behnam, Buckley, Dennis L., Guo, Yang Eric, Hnisz, Denes, Jaenisch, Rudolf, Bradner, James E., Gray, Nathanael S., Young, Richard A.

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Pol II phosphorylation regulates a switch between transcriptional and splicing condensates von Guo, Yang Eric, Manteiga, John C., Henninger, Jonathan E., Sabari, Benjamin R., Dall’Agnese, Alessandra, Hannett, Nancy M., Spille, Jan-Hendrik, Afeyan, Lena K., Zamudio, Alicia V., Shrinivas, Krishna, Abraham, Brian J., Boija, Ann, Decker, Tim-Michael, Rimel, Jenna K., Fant, Charli B., Lee, Tong Ihn, Cisse, Ibrahim I., Sharp, Phillip A., Taatjes, Dylan J., Young, Richard A.

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Models of human core transcriptional regulatory circuitries von Saint-André, Violaine, Federation, Alexander J, Lin, Charles Y, Abraham, Brian J, Reddy, Jessica, Lee, Tong Ihn, Bradner, James E, Young, Richard A

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Coactivator condensation at super-enhancers links phase separation and gene control von Sabari, Benjamin R, Dall'Agnese, Alessandra, Boija, Ann, Klein, Isaac A, Coffey, Eliot L, Shrinivas, Krishna, Abraham, Brian J, Hannett, Nancy M, Zamudio, Alicia V, Manteiga, John C, Li, Charles H, Guo, Yang E, Day, Daniel S, Schuijers, Jurian, Vasile, Eliza, Malik, Sohail, Hnisz, Denes, Lee, Tong Ihn, Cisse, Ibrahim I, Roeder, Robert G, Sharp, Phillip A, Chakraborty, Arup K, Young, Richard A

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Genome-wide Analyses of Transcription Factor GATA3-Mediated Gene Regulation in Distinct T Cell Types von Wei, Gang, Abraham, Brian J., Yagi, Ryoji, Jothi, Raja, Cui, Kairong, Sharma, Suveena, Narlikar, Leelavati, Northrup, Daniel L., Tang, Qingsong, Paul, William E., Zhu, Jinfang, Zhao, Keji

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Transcription factor trapping by RNA in gene regulatory elements von Sigova, Alla A., Abraham, Brian J., Ji, Xiong, Molinie, Benoit, Hannett, Nancy M., Guo, Yang Eric, Jangi, Mohini, Giallourakis, Cosmas C., Sharp, Phillip A., Young, Richard A.

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CDK7-Dependent Transcriptional Addiction in Triple-Negative Breast Cancer von Wang, Yubao, Zhang, Tinghu, Kwiatkowski, Nicholas, Abraham, Brian J., Lee, Tong Ihn, Xie, Shaozhen, Yuzugullu, Haluk, Von, Thanh, Li, Heyuan, Lin, Ziao, Stover, Daniel G., Lim, Elgene, Wang, Zhigang C., Iglehart, J. Dirk, Young, Richard A., Gray, Nathanael S., Zhao, Jean J.

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An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element von Mansour, Marc R., Abraham, Brian J., Anders, Lars, Berezovskaya, Alla, Gutierrez, Alejandro, Durbin, Adam D., Etchin, Julia, Lawton, Lee, Sallan, Stephen E., Silverman, Lewis B., Loh, Mignon L., Hunger, Stephen P., Sanda, Takaomi, Young, Richard A., Look, A. Thomas

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SEAseq: a portable and cloud-based chromatin occupancy analysis suite von Adetunji, Modupeore O, Abraham, Brian J

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A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer von Betancur, Paola A., Abraham, Brian J., Yiu, Ying Y., Willingham, Stephen B., Khameneh, Farnaz, Zarnegar, Mark, Kuo, Angera H., McKenna, Kelly, Kojima, Yoko, Leeper, Nicholas J., Ho, Po, Gip, Phung, Swigut, Tomek, Sherwood, Richard I., Clarke, Michael F., Somlo, George, Young, Richard A., Weissman, Irving L.

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Targeting Transcriptional Addictions in Small Cell Lung Cancer with a Covalent CDK7 Inhibitor von Christensen, Camilla L., Kwiatkowski, Nicholas, Abraham, Brian J., Carretero, Julian, Al-Shahrour, Fatima, Zhang, Tinghu, Chipumuro, Edmond, Herter-Sprie, Grit S., Akbay, Esra A., Altabef, Abigail, Zhang, Jianming, Shimamura, Takeshi, Capelletti, Marzia, Reibel, Jakob B., Cavanaugh, Jillian D., Gao, Peng, Liu, Yan, Michaelsen, Signe R., Poulsen, Hans S., Aref, Amir R., Barbie, David A., Bradner, James E., George, Rani E., Gray, Nathanael S., Young, Richard A., Wong, Kwok-Kin

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MYC Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification von Zimmerman, Mark W, Liu, Yu, He, Shuning, Durbin, Adam D, Abraham, Brian J, Easton, John, Shao, Ying, Xu, Beisi, Zhu, Shizhen, Zhang, Xiaoling, Li, Zhaodong, Weichert-Leahey, Nina, Young, Richard A, Zhang, Jinghui, Look, A Thomas

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The Developmental Potential of iPSCs Is Greatly Influenced by Reprogramming Factor Selection von Buganim, Yosef, Markoulaki, Styliani, van Wietmarschen, Niek, Hoke, Heather, Wu, Tao, Ganz, Kibibi, Akhtar-Zaidi, Batool, He, Yupeng, Abraham, Brian J., Porubsky, David, Kulenkampff, Elisabeth, Faddah, Dina A., Shi, Linyu, Gao, Qing, Sarkar, Sovan, Cohen, Malkiel, Goldmann, Johanna, Nery, Joseph R., Schultz, Matthew D., Ecker, Joseph R., Xiao, Andrew, Young, Richard A., Lansdorp, Peter M., Jaenisch, Rudolf

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Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism von Oldridge, Derek A., Wood, Andrew C., Weichert-Leahey, Nina, Crimmins, Ian, Sussman, Robyn, Winter, Cynthia, McDaniel, Lee D., Diamond, Maura, Hart, Lori S., Zhu, Shizhen, Durbin, Adam D., Abraham, Brian J., Anders, Lars, Tian, Lifeng, Zhang, Shile, Wei, Jun S., Khan, Javed, Bramlett, Kelli, Rahman, Nazneen, Capasso, Mario, Iolascon, Achille, Gerhard, Daniela S., Guidry Auvil, Jaime M., Young, Richard A., Hakonarson, Hakon, Diskin, Sharon J., Thomas Look, A., Maris, John M.

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Chromatin proteomic profiling reveals novel proteins associated with histone-marked genomic regions von Ji, Xiong, Dadon, Daniel B., Abraham, Brian J., Lee, Tong Ihn, Jaenisch, Rudolf, Bradner, James E., Young, Richard A.

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Small genomic insertions form enhancers that misregulate oncogenes von Abraham, Brian J., Hnisz, Denes, Weintraub, Abraham S., Kwiatkowski, Nicholas, Li, Charles H., Li, Zhaodong, Weichert-Leahey, Nina, Rahman, Sunniyat, Liu, Yu, Etchin, Julia, Li, Benshang, Shen, Shuhong, Lee, Tong Ihn, Zhang, Jinghui, Look, A. Thomas, Mansour, Marc R., Young, Richard A.

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