The Intriguing Sigma-1 and Sigma-2 Receptors and Their Potential Therapeutic Roles 2.0 von Abate, Carmen, Maurice, Tangui

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σ2 Receptor and Its Role in Cancer with Focus on a MultiTarget Directed Ligand (MTDL) Approach von Abatematteo, Francesca Serena, Niso, Mauro, Lacivita, Enza, Abate, Carmen

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Live imaging reveals a new role for the sigma-1 (σ1) receptor in allowing microglia to leave brain injuries von Moritz, Christian, Berardi, Francesco, Abate, Carmen, Peri, Francesca

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Multi-Target Directed Ligands (MTDLs) Binding the σ1 Receptor as Promising Therapeutics: State of the Art and Perspectives von Abatematteo, Francesca Serena, Niso, Mauro, Contino, Marialessandra, Leopoldo, Marcello, Abate, Carmen

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PB28, the Sigma-1 and Sigma-2 Receptors Modulator With Potent Anti-SARS-CoV-2 Activity: A Review About Its Pharmacological Properties and Structure Affinity Relationships von Abate, Carmen, Niso, Mauro, Abatematteo, Francesca Serena, Contino, Marialessandra, Colabufo, Nicola Antonio, Berardi, Francesco

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MRP1-Collateral Sensitizers as a Novel Therapeutic Approach in Resistant Cancer Therapy: An In Vitro and In Vivo Study in Lung Resistant Tumor von Riganti, Chiara, Giampietro, Roberta, Kopecka, Joanna, Costamagna, Costanzo, Abatematteo, Francesca Serena, Contino, Marialessandra, Abate, Carmen

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Design and Synthesis of Arylpiperazine Serotonergic/Dopaminergic Ligands with Neuroprotective Properties von Mastromarino, Margherita, Niso, Mauro, Abate, Carmen, Proschak, Ewgenij, Dubiel, Mariam, Stark, Holger, Castro, Marián, Lacivita, Enza, Leopoldo, Marcello

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A conformational rearrangement of the SARS-CoV-2 host protein sigma-1 is required for antiviral activity: insights from a combined in-silico/in-vitro approach von Abatematteo, Francesca Serena, Delre, Pietro, Mercurio, Ivan, Rezelj, Veronica V., Siliqi, Dritan, Beaucourt, Stephanie, Lattanzi, Gianluca, Colabufo, Nicola Antonio, Leopoldo, Marcello, Saviano, Michele, Vignuzzi, Marco, Mangiatordi, Giuseppe Felice, Abate, Carmen

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New Pharmacological Strategies against Pancreatic Adenocarcinoma: The Multifunctional Thiosemicarbazone FA4 von Anobile, Dario P, Niso, Mauro, Puerta, Adrian, Fraga Rodrigues, Stephanie M, Abatematteo, Francesca S, Avan, Amir, Abate, Carmen, Riganti, Chiara, Giovannetti, Elisa

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Sigma-2 receptor/TMEM97 agonist PB221 as an alternative drug for brain tumor von Liu, Chia-Chi, Yu, Ching-Fang, Wang, Shu-Chi, Li, Hsueh-Yin, Lin, Chiu-Min, Wang, Hsia-Han, Abate, Carmen, Chiang, Chi-Shiun

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Sigma-2 Receptor Ligand Binding Modulates Association between TSPO and TMEM97 von Thejer, Bashar M, Infantino, Vittoria, Santarsiero, Anna, Pappalardo, Ilaria, Abatematteo, Francesca S, Teakel, Sarah, Van Oosterum, Ashleigh, Mach, Robert H, Denora, Nunzio, Lee, Byung Chul, Resta, Nicoletta, Bagnulo, Rosanna, Niso, Mauro, Contino, Marialessandra, Montsch, Bianca, Heffeter, Petra, Abate, Carmen, Cahill, Michael A

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NO1, a New Sigma 2 Receptor/TMEM97 Fluorescent Ligand, Downregulates SOCE and Promotes Apoptosis in the Triple Negative Breast Cancer Cell Lines von Cantonero, Carlos, Javier Camello, Pedro, Abate, Carmen, Berardi, Francesco, Maria Salido, Gines, Antonio Rosado, Juan, Redondo, Pedro C.

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Sigma-2 Receptor Agonists as Possible Antitumor Agents in Resistant Tumors: Hints for Collateral Sensitivity von Niso, Mauro, Abate, Carmen, Contino, Marialessandra, Ferorelli, Savina, Azzariti, Amalia, Perrone, Roberto, Colabufo, Nicola Antonio, Berardi, Francesco

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Lysosomal membrane permeabilization is an early event in Sigma-2 receptor ligand mediated cell death in pancreatic cancer von Hornick, John R, Vangveravong, Suwanna, Spitzer, Dirk, Abate, Carmen, Berardi, Francesco, Goedegebuure, Peter, Mach, Robert H, Hawkins, William G

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Sigma-2 receptor: past, present and perspectives on multiple therapeutic exploitations von Abate, Carmen, Niso, Mauro, Berardi, Francesco

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Is the σ2 Receptor a Histone Binding Protein? von Colabufo, Nicola Antonio, Berardi, Francesco, Abate, Carmen, Contino, Marialessandra, Niso, Mauro, Perrone, Roberto

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Elements in support of the ‘non-identity’ of the PGRMC1 protein with the σ2 receptor von Abate, Carmen, Niso, Mauro, Infantino, Vittoria, Menga, Alessio, Berardi, Francesco

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Synthesis and pharmacological evaluation of 11C-labeled piperazine derivative as a PET probe for sigma-2 receptor imaging von Selivanova, Svetlana V., Toscano, Annamaria, Abate, Carmen, Berardi, Francesco, Müller, Adrienne, Krämer, Stefanie D., Schibli, Roger, Ametamey, Simon M.

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Perspectives of Cannabinoid Type 2 Receptor (CB2R) Ligands in Neurodegenerative Disorders: Structure-Affinity Relationship (SAfiR) and Structure-Activity Relationship (SAR) Studies von Spinelli, Francesco, Capparelli, Elena, Abate, Carmen, Colabufo, Nicola A, Contino, Marialessandra

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PB183, a sigma receptor ligand, as a potential PET probe for the imaging of prostate adenocarcinoma von Colabufo, Nicola Antonio, Abate, Carmen, Contino, Marialessandra, Inglese, Carmela, Niso, Mauro, Berardi, Francesco, Perrone, Roberto

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