Total Synthesis of the Strychnos Alkaloid (+)-Minfiensine: Tandem Enantioselective Intramolecular Heck−Iminium Ion Cyclization von Dounay, Amy B, Humphreys, Philip G, Overman, Larry E, Wrobleski, Aaron D

Volltext

Sequential Catalytic Asymmetric Heck−Iminium Ion Cyclization:  Enantioselective Total Synthesis of the Strychnos Alkaloid Minfiensine von Dounay, Amy B, Overman, Larry E, Wrobleski, Aaron D

Volltext

Regioselective Single and Double Conjugate Additions to Substituted Cyclohexa-2,5-dienone Monoacetals von Grecian, Scott, Wrobleski, Aaron D, Aubé, Jeffrey

Volltext

Discovery of 1‑(3,3-Dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)­pyrido[2,3‑d]pyrimidin-6-yl)phenyl)urea (LY3009120) as a Pan-RAF Inhibitor with Minimal Paradoxi... von Henry, James R, Kaufman, Michael D, Peng, Sheng-Bin, Ahn, Yu Mi, Caldwell, Timothy M, Vogeti, Lakshminarayana, Telikepalli, Hanumaiah, Lu, Wei-Ping, Hood, Molly M, Rutkoski, Thomas J, Smith, Bryan D, Vogeti, Subha, Miller, David, Wise, Scott C, Chun, Lawrence, Zhang, Xiaoyi, Zhang, Youyan, Kays, Lisa, Hipskind, Philip A, Wrobleski, Aaron D, Lobb, Karen L, Clay, Julia M, Cohen, Jeffrey D, Walgren, Jennie L, McCann, Denis, Patel, Phenil, Clawson, David K, Guo, Sherry, Manglicmot, Danalyn, Groshong, Chris, Logan, Cheyenne, Starling, James J, Flynn, Daniel L

Volltext

Facile C−N Cleavage in a Series of Bridged Lactams von Lei, Yao, Wrobleski, Aaron D, Golden, Jennifer E, Powell, Douglas R, Aubé, Jeffrey

Volltext

Double Diastereoselective Intramolecular Cyclopropanation to P-Chiral [3.1.0]-Bicyclic Phosphonates von Moore, Joel D, Sprott, Kevin T, Wrobleski, Aaron D, Hanson, Paul R

Volltext

Sequential Catalytic Asymmetric Heck-Iminium Ion Cyclization:  Enantioselective Total Synthesis of the Strychnos Alkaloid Minfiensine  [J. Am. Chem. Soc. 2005, 127, 10186−10187].... von Dounay, Amy B, Overman, Larry E, Wrobleski, Aaron D

Volltext

Abstract 353: A novel molecule with profound tumor killing activity von Liu, Ling, Wrobleski, Aaron D., Yin, Yin, Zeng, Wei, Chen, Xianming, Stokell, David J., Peng, Sheng-bin, Datta-Mannan, Amita, Donoho, Gregory P., Iversen, Philip W., Hipskind, Philip, Feng, Yiqing

Volltext

Sequential catalytic asymmetric heck-lminium ion cyclization : Enantioselective total synthesis of the Strychnos alkaloid minfiensine von DOUNAY, Amy B, OVERMAN, Larry E, WROBLESKI, Aaron D

Volltext

Composés inhibiteurs de la voie de signalisation de notch von GILL, John C, HIPSKIND, Philip Arthur, EDGE, Albert, VAN ES, Helmuth Hendrikus Gerardus, CLAY, Julia Marie, PATEL, Bharvin Kumar, WROBLESKI, Aaron D, ZHAO, Gaiying

Volltext bestellen

Intramolecular cyclopropanation reactions en route to novel P-heterocycles von Hanson, Paul R., Sprott, Kevin T., Wrobleski, Aaron D.

Volltext

NOTCH PATHWAY SIGNALING INHIBITOR COMPOUNDS von HELMUTH HENDRIKUS GERARDUS VAN ES, ALBERT EDGE, BHARVIN KUMAR PATEL, AARON D. WROBLESKI, GAIYING ZHAO, JOHN C. GILL, PHILIP ARTHUR HIPSKIND, JULIA MARIE CLAY

Volltext bestellen

NOTCH PATHWAY SIGNALING INHIBITOR COMPOUNDS von GILL, John C, HIPSKIND, Philip Arthur, EDGE, Albert, VAN ES, Helmuth Hendrikus Gerardus, CLAY, Julia Marie, PATEL, Bharvin Kumar, WROBLESKI, Aaron D, ZHAO, Gaiying

Volltext bestellen

NOTCH PATHWAY SIGNALING INHIBITOR COMPOUNDS von GILL, John C, HIPSKIND, Philip Arthur, EDGE, Albert, VAN ES, Helmuth Hendrikus Gerardus, CLAY, Julia Marie, PATEL, Bharvin Kumar, WROBLESKI, Aaron D, ZHAO, Gaiying

Volltext bestellen

NOTCH PATHWAY SIGNALING INHIBITOR COMPOUNDS von GILL, John C, HIPSKIND, Philip Arthur, EDGE, Albert, VAN ES, Helmuth Hendrikus Gerardus, CLAY, Julia Marie, PATEL, Bharvin Kumar, WROBLESKI, Aaron D, ZHAO, Gaiying

Volltext bestellen

NOTCH PATHWAY SIGNALING INHIBITOR COMPOUNDS von HIPSKIND, PHILIP ARTHUR, PATEL, BHARVIN KUMAR, WROBLESKI, AARON D, ZHAO, GAIYING, CLAY, JULIA MARIE, EDGE, ALBERT, GILL, JOHN C, VAN ES, HELMUTH HENDRIKUS GERARDUS

Volltext bestellen

NOTCH PATHWAY SIGNALING INHIBITOR COMPOUNDS von HIPSKIND, PHILIP ARTHUR, PATEL, BHARVIN KUMAR, WROBLESKI, AARON D, ZHAO, GAIYING, CLAY, JULIA MARIE, EDGE, ALBERT, GILL, JOHN C, VAN ES, HELMUTH HENDRIKUS GERARDUS

Volltext bestellen

Notch pathway signaling inhibitor compounds von Gill, John C, Van Es, Helmuth Hendrikus Gerardus, Edge, Albert, Zhao, Gaiying, Hipskind, Philip Arthur, Wrobleski, Aaron D, Clay, Julia Marie, Patel, Bharvin Kumar

Volltext bestellen

NOTCH PATHWAY SIGNALING INHIBITOR COMPOUNDS von Gill, John C, Van Es, Helmuth Hendrikus Gerardus, Edge, Albert, Zhao, Gaiying, Hipskind, Philip Arthur, Wrobleski, Aaron D, Clay, Julia Marie, Patel, Bharvin Kumar

Volltext bestellen

NOTCH PATHWAY SIGNALING INHIBITOR COMPOUNDS von HIPSKIND, PHILIP ARTHUR, PATEL, BHARVIN KUMAR, WROBLESKI, AARON D, ZHAO, GAIYING, CLAY, JULIA MARIE, EDGE, ALBERT, GILL, JOHN C, VAN ES, HELMUTH HENDRIKUS GERARDUS

Volltext bestellen