Extended exposure to low doses of azacitidine induces differentiation of leukemic stem cells through activation of myeloperoxidase von Jeyaraju, Danny V, Alapa, Maryam, Polonskaia, Ann, Risueño, Alberto, Subramanyam, Prakash, Anand, Amit, Ghosh, Kaushik, Kyriakopoulos, Charalampos, Hemerich, Daiane, Hurren, Rose, Wang, Xiaoming, Gronda, Marcela, Ahsan, Aarif, Chiu, Hsiling, Thomas, Geethu, Lind, Evan F, Menezes, Daniel L, Schimmer, Aaron D, Hagner, Patrick R, Gandhi, Anita, Thakurta, Anjan G

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KRAS Protein Stability Is Regulated through SMURF2: UBCH5 Complex-Mediated β-TrCP1 Degradation von Shukla, Shirish, Allam, Uday Sankar, Ahsan, Aarif, Chen, Guoan, Krishnamurthy, Pranathi Meda, Marsh, Katherine, Rumschlag, Matthew, Shankar, Sunita, Whitehead, Christopher, Schipper, Matthew, Basrur, Venkatesha, Southworth, Daniel R, Chinnaiyan, Arul M, Rehemtulla, Alnawaz, Beer, David G, Lawrence, Theodore S, Nyati, Mukesh K, Ray, Dipankar

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Membrane Transition Temperature Determines Cisplatin Response von Raghunathan, Krishnan, Ahsan, Aarif, Ray, Dipankar, Nyati, Mukesh K, Veatch, Sarah L

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Wild-type EGFR Is Stabilized by Direct Interaction with HSP90 in Cancer Cells and Tumors von Ahsan, Aarif, Ramanand, Susmita G, Whitehead, Christopher, Hiniker, Susan M, Rehemtulla, Alnawaz, Pratt, William B, Jolly, Shruti, Gouveia, Christopher, Truong, Kristy, Waes, Carter Van, Ray, Dipankar, Lawrence, Theodore S, Nyati, Mukesh K

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P693: LUSPATERCEPT RESTORES EFFECTIVE ERYTHROPOIESIS AND PROVIDES SUPERIOR AND SUSTAINED CLINICAL BENEFIT VS EPOETIN ALFA: BIOMARKER ANALYSIS FROM THE PHASE 3 COMMANDS STUDY von Platzbecker, Uwe, Hayati, Sheida, Ahsan, Aarif, Verma, Amit, Aluri, Srinivas, Rose, Shelonitda, Gandhi, Anita, Nvs Suragani, Rajasekhar, Vodala, Sadanand

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Efficacy of an EGFR-Specific Peptide against EGFR-Dependent Cancer Cell Lines and Tumor Xenografts von Ahsan, Aarif, Ramanand, Susmita G, Bergin, Ingrid L, Zhao, Lilli, Whitehead, Christopher E, Rehemtulla, Alnawaz, Ray, Dipankar, Pratt, William B, Lawrence, Theodore S, Nyati, Mukesh K

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Role of Epidermal Growth Factor Receptor Degradation in Cisplatin-Induced Cytotoxicity in Head and Neck Cancer von AHSAN, Aarif, HINIKER, Susan M, RAMANAND, Susmita G, NYATI, Shyam, HEGDE, Ashok, HELMAN, Abigail, MENAWAT, Radhika, BHOJANI, Mahaveer S, LAWRENCE, Theodore S, NYATI, Mukesh K

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P697: DISTINCT SPLICING ALTERATIONS ASSOCIATED WITH CLINICAL RESPONSE TO LUSPATERCEPT IN PATIENTS WITH LOWER‑RISK MYELODYSPLASTIC SYNDROMES FROM THE MEDALIST STUDY von Aluri, Srinivas, Ahsan, Aarif, Hayati, Sheida, Ugidos, Manuel, Shah, Punit, Lizotte, Kate, Chakraborty, Samarpana, Pradhan, Kith, Sahu, Srabani, Maqbool, Shahina, Shastri, Aditi, Dongre, Ashok, Platzbecker, Uwe, Gandhi, Anita, Nvs Suragani, Rajasekhar, Vodala, Sadanand, Verma, Amit

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Regulation of EGFR Protein Stability by the HECT-type Ubiquitin Ligase SMURF2 von Ray, Dipankar, Ahsan, Aarif, Helman, Abigail, Chen, Guoan, Hegde, Ashok, Gurjar, Susmita Ramanand, Zhao, Lili, Kiyokawa, Hiroaki, Beer, David G, Lawrence, Theodore S, Nyati, Mukesh K

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Heterozygotes of NOS3 Polymorphisms Contribute to Reduced Nitrogen Oxides in High-Altitude Pulmonary Edema von Ahsan, Aarif, Mohd, Ghulam, Norboo, Tsering, Baig, Masroor A., Pasha, M. A. Qadar

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Endothelial nitric oxide synthase gene variants contribute to oxidative stress in COPD von Arif, Ehtesham, Ahsan, Aarif, Vibhuti, Arpana, Rajput, Charu, Deepak, Desh, Athar, Mohammad, Singh, Bhawani, Pasha, M.A. Qadar

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Abstract 450: A targeted capture panel to identify translocations, copy number abnormalities, and mutations in multiple myeloma von Walker, Brian Andrew, Ahsan, Aarif, Sudha, Parvathi, Kausar, Tasneem, Rane, Sushmita, Flynt, Erin, Thakurta, Anjan

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Ionotropic receptors mediate olfactory learning and memory in Drosophila von Ali, Md Zeeshan, Anushree, Ahsan, Aarif, Ola, Mohammad Shamsul, Haque, Rizwanul, Ahsan, Jawaid

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RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer von Wang, Wei, Marinis, Jill M., Beal, Allison M., Savadkar, Shivraj, Wu, Yue, Khan, Mohammed, Taunk, Pardeep S., Wu, Nan, Su, Wenyu, Wu, Jingjing, Ahsan, Aarif, Kurz, Emma, Chen, Ting, Yaboh, Inedouye, Li, Fei, Gutierrez, Johana, Diskin, Brian, Hundeyin, Mautin, Reilly, Michael, Lich, John D., Harris, Philip A., Mahajan, Mukesh K., Thorpe, James H., Nassau, Pamela, Mosley, Julie E., Leinwand, Joshua, Kochen Rossi, Juan A., Mishra, Ankita, Aykut, Berk, Glacken, Michael, Ochi, Atsuo, Verma, Narendra, Kim, Jacqueline I., Vasudevaraja, Varshini, Adeegbe, Dennis, Almonte, Christina, Bagdatlioglu, Ece, Cohen, Deirdre J., Wong, Kwok-Kin, Bertin, John, Miller, George

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Bivalent BCMA Binding and Low Affinity CD3 T-Cell Engagement By Abbv-383 Drives Sustained Activation with Reduced T-Cell Exhaustion in Preclinical Models of Multiple Myeloma von Sharon, David, Robinson, Valerie, Hecquet, Claudie, Calabrese, Kelly, Cosgrove, Cormac, Mantis, Christine, Bueno, Orlando, Ahsan, Aarif, Chervin, Adam, Epling-Burnette, PK, Ross, Jeremy A

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Luspatercept Modulates Inflammation in the Bone Marrow, Restores Effective Erythropoiesis/Hematopoiesis, and Provides Sustained Clinical Benefit Versus Epoetin Alfa (EA): Biomarker... von Hayati, Sheida, Zeidan, Amer M., Garcia-Manero, Guillermo, Platzbecker, Uwe, Ahsan, Aarif, Verma, Amit K., Aluri, Srinivas, Guerrero, Manuel Ugidos, Gandhi, Anita K., Suragani, Rajasekhar N.V.S., Vodala, Sadanand

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Investigations into the Mechanisms and Clinical Implications of Modulation of Hepcidin Levels By Luspatercept in TD MDS and TD b-Thalassemia von Ahsan, Aarif, Fang, Wei, Ugidos, Manuel, Jeyaraju, Danny V, Fenaux, Pierre, Platzbecker, Uwe, Hermine, Olivier, Porter, John B., Suragani, Rajasekhar N.V.S., Vodala, Sadanand, Gandhi, Anita K.

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Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression von Sreekumar, Arun, Poisson, Laila M., Rajendiran, Thekkelnaycke M., Khan, Amjad P., Cao, Qi, Yu, Jindan, Laxman, Bharathi, Mehra, Rohit, Lonigro, Robert J., Li, Yong, Nyati, Mukesh K., Ahsan, Aarif, Kalyana-Sundaram, Shanker, Han, Bo, Cao, Xuhong, Byun, Jaeman, Omenn, Gilbert S., Ghosh, Debashis, Pennathur, Subramaniam, Alexander, Danny C., Berger, Alvin, Shuster, Jeffrey R., Wei, John T., Varambally, Sooryanarayana, Beecher, Christopher, Chinnaiyan, Arul M.

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Phenylacetaldehyde induced olfactory conditioning in Drosophila melanogaster (Diptera: Drosophilidae) larvae von Ali, Md Zeeshan, Anushree, Anushree, Bilgrami, Anwar L, Ahsan, Aarif, Ola, Mohammad Shamsul, Haque, Rizwanul, Ahsan, Jawaid

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Phenylacetaldehyde induced olfactory conditioning in Drosophila melanogaster von Ali, Md Zeeshan, Anushree, Anushree, Bilgrami, Anwar L, Ahsan, Aarif, Ola, Mohammad Shamsul, Haque, Rizwanul, Ahsan, Jawaid

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