Carriage of the PNPLA3 rs738409 C >G polymorphism confers an increased risk of non-alcoholic fatty liver disease associated hepatocellular carcinoma von Liu, Y.-L, Patman, G.L, Leathart, J.B.S, Piguet, A.-C, Burt, A.D, Dufour, J.-F, Day, C.P, Daly, A.K, Reeves, H.L, Anstee, Q.M

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Pathogenesis of FOLFOX induced sinusoidal obstruction syndrome in a murine chemotherapy model von Robinson, S.M, Mann, J, Vasilaki, A, Mathers, J, Burt, A.D, Oakley, F, White, S.A, Mann, D.A

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Autonomic function is impaired across the spectrum of NAFLD von Houghton, D, Zalewski, P, Cassidy, S, Thoma, C, Hallsworth, K, Avery, L, Lukowska, A.B, Hardy, T, Burt, A.D, Masson, S, Day, C, McPherson, S, Anstee, Q.M, Newton, J.L, Trenell, M.I

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597 METHAPYRILENE TREATMENT IS A REFINED ALTERNATIVE TO BILE DUCT LIGATION AS A MODEL OF REPRODUCIBLE AND REVERSIBLE PERIPORTAL FIBROSIS IN THE RAT von Probert, P.M.E, Ebrahimkhani, M.R, Oakley, F, Burt, A.D, Mann, D.A, Wright, M.C

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1078 ENHANCED LIVER FIBROSIS TEST ACCURATELY IDENTIFIES LIVER FIBROSIS AND PREDICTS CLINICAL OUTCOMES IN ALCOHOLIC LIVER DISEASE von Trembling, P.M, Parkes, J, Tanwar, S, Burt, A.D, Rosenberg, W.M

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1362 CLINICAL BUT NOT HISTOLOGICAL FACTORS PREDICT LONG-TERM PROGNOSIS IN PATIENTS WITH BIOPSY PROVEN ADVANCED ALCOHOLIC LIVER DISEASE von Masson, S, Emmerson, I, Henderson, E, Fletcher, E, Burt, A.D, Day, C.P, Stewart, S.F

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1282 MILD STEATOSIS AND IMPAIRED GLUCOSE TOLERANCE ARE ASSOCIATED WITH LIVER CANCER DEVELOPMENT, WHILE PROGRESSION TO NASH INCREASES NUMBER/SIZE IN AN ANIMAL MODEL OF NAFLD von Patman, G.L, Televantou, D, Whitehead, A, Day, C.P, Oakley, F, Mann, D.A, Burt, A.D, Anstee, Q.M, Reeves, H.L

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1290 SULFATASE-2 (SULF2) EXPRESSED IN HEPATOCYTES AND STROMAL CELLS CONTRIBUTES TO THE DEVELOPMENT OF STEATOSIS, THE PROGRESSION OF NAFLD TO FIBROSIS AND THE ADVANCEMENT OF CANCER von Patman, G.L, Televantou, D, Whitehead, A, Piguet, A.-C, Dufour, J.F, Day, C.P, Burt, A.D, Mann, D.A, Reeves, H.L

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118 PROTECTIVE ADAPTATION TO LIVER FIBROSIS IN A SINGLE GENERATION BY HERITABLE EPIGENETIC MODIFICATIONS von Zeybel, M, Oakley, F, Burt, A.D, Mann, D.A, Mann, J

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Determinants of progression to cirrhosis or fibrosis in pure alcoholic fatty liver von Teli, M.R, Day, C.P, James, O.F.W, Burt, A.D, Bennett, M.K

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1308 A ROLE FOR DNA REPAIR PROTEIN KINASE (DNA-PK) IN THE PROGRESSION OF SIMPLE STEATOSIS TO STEATOHEPATITIS (NASH)? von Whitehead, A, Patman, G.L, Cornell, L, Televantou, D, Curtin, N, Day, C.P, Burt, A.D, Piguet, A.-C, Dufour, J.F, Anstee, Q.M, Reeves, H.L

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1100 PROLONGED GLUCOCORTICOID EXPOSURE RESULTS IN THE APPEARANCE OF HEPATOCYTES IN THE ADULT PANCREAS von Wallace, K, Shaw, J, White, S.A, Wright, S, Burt, A.D, Wright, M.C

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Results of a Two-Center Study Comparing Hepatic Fibrosis Progression in HCV-positive Liver Transplant Patients Receiving Cyclosporine or Tacrolimus von van der Laan, L.J.W, Hudson, M, McPherson, S, Zondervan, P.E, Thomas, R.C, Kwekkeboom, J, Lindsay, A.S, Burt, A.D, Kazemier, G, Tilanus, H.W, Bassendine, M.F, Metselaar, H.J

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900 RECOMBINANT LYSOSOMAL ACID LIPASE NORMALIZES LIVER WEIGHT, TRANSAMINASES AND HISTOPATHOLOGICAL ABNORMALITIES IN AN MODEL OF CHOLESTERYL ESTER STORAGE DISEASE von Leavitt, M, Burt, A.D, Hu, W, Canty, D, Gray, M, Bray, A, Harvey, A, Day, C.P, Ouinn, A.G

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53 ATTENUATED INFLAMMATORY RESPONSE IN FIBROTIC LIVERS OF MICE LACKING THE C-REL SUBUNIT OF NF-KB von Elsharkawy, A.M, Gieling, R.G, Oakley, F, Kendall, T, Burt, A.D, Mann, D.A

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Biliary Epithelial Senescence and Plasticity in Acute Cellular Rejection von Brain, J. G., Robertson, H., Thompson, E., Humphreys, E. H., Gardner, A., Booth, T. A., Jones, D. E. J., Afford, S. C., von Zglinicki, T., Burt, A. D., Kirby, J. A.

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Mutations in CHD7 in patients with CHARGE syndrome cause T-B + natural killer cell + severe combined immune deficiency and may cause Omenn-like syndrome von Gennery, A.R, Slatter, M.A, Rice, J, Hoefsloot, L.H, Barge, D, McLean-Tooke, A, Montgomery, T, Goodship, J.A, Burt, A.D, Flood, T.J, Abinun, M, Cant, A.J, Johnson, D

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Hepatitis and liver dysfunction with rifampicin therapy for pruritus in primary biliary cirrhosis von Prince, M I, Burt, A D, Jones, D E J

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THU-349 - Autonomic function is impaired across the spectrum of NAFLD von Houghton, D., Zalewski, P., Cassidy, S., Thoma, C., Hallsworth, K., Avery, L., Lukowska, A.B., Hardy, T., Burt, A.D., Masson, S., Day, C., McPherson, S., Anstee, Q.M., Newton, J.L., Trenell, M.I.

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Chronic Allograft Nephropathy: Intraepithelial Signals Generated by Transforming Growth Factor‐β and Bone Morphogenetic Protein‐7 von Tyler, J. R., Robertson, H., Booth, T. A., Burt, A. D., Kirby, J. A.

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