Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors von Prabhu, Varun V, Lulla, Amriti R, Madhukar, Neel S, Ralff, Marie D, Zhao, Dan, Kline, Christina Leah B, Van den Heuvel, A Pieter J, Lev, Avital, Garnett, Mathew J, McDermott, Ultan, Benes, Cyril H, Batchelor, Tracy T, Chi, Andrew S, Elemento, Olivier, Allen, Joshua E, El-Deiry, Wafik S

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Direct control of caveolin-1 expression by FOXO transcription factors von van den Heuvel, A Pieter J, Schulze, Almut, Burgering, Boudewijn M T

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Analysis of glutamine dependency in non-small cell lung cancer: GLS1 splice variant GAC is essential for cancer cell growth von van den Heuvel, A. Pieter J., Jing, Junping, Wooster, Richard F., Bachman, Kurtis E.

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Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53 von Zhang, Shengliang, Zhou, Lanlan, Hong, Bo, van den Heuvel, A Pieter J, Prabhu, Varun V, Warfel, Noel A, Kline, Christina Leah B, Dicker, David T, Kopelovich, Levy, El-Deiry, Wafik S

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Novel common integration sites targeted by mouse mammary tumor virus insertion in mammary tumors have oncogenic activity von Kim, Hyoung H, van den Heuvel, A Pieter J, Schmidt, John W, Ross, Susan R

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Prodigiosin Rescues Deficient p53 Signaling and Antitumor Effects via Upregulating p73 and Disrupting Its Interaction with Mutant p53 von BO HONG, PRABHU, Varun V, SHENGLIANG ZHANG, VAN DEN HEUVEL, A. Pieter J, DICKER, David T, KOPELOVICH, Levy, EL-DEIRY, Wafik S

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Genetic and Pharmacological Screens Converge in Identifying FLIP, BCL2, and IAP Proteins as Key Regulators of Sensitivity to the TRAIL-Inducing Anticancer Agent ONC201/TIC10 von Allen, Joshua E, Prabhu, Varun V, Talekar, Mala, van den Heuvel, A Pieter J, Lim, Bora, Dicker, David T, Fritz, Jennifer L, Beck, Adam, El-Deiry, Wafik S

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Binding of protein kinase B to the plakin family member periplakin von van den Heuvel, A Pieter J, de Vries-Smits, Alida M M, van Weeren, Pascale C, Dijkers, Pascale F, de Bruyn, Kim M T, Riedl, Jürgen A, Burgering, Boudewijn M T

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ONC201 kills solid tumor cells by triggering an integrated stress response dependent on ATF4 activation by specific eIF2α kinases von Kline, C Leah B, Van den Heuvel, A Pieter J, Allen, Joshua E, Prabhu, Varun V, Dicker, David T, El-Deiry, Wafik S

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Single agent and synergistic combinatorial efficacy of first-in-class small molecule imipridone ONC201 in hematological malignancies von Prabhu, Varun V, Talekar, Mala K, Lulla, Amriti R, Kline, C Leah B, Zhou, Lanlan, Hall, Junior, Van den Heuvel, A Pieter J, Dicker, David T, Babar, Jawad, Grupp, Stephan A, Garnett, Mathew J, McDermott, Ultan, Benes, Cyril H, Pu, Jeffrey J, Claxton, David F, Khan, Nadia, Oster, Wolfgang, Allen, Joshua E, El-Deiry, Wafik S

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Single Agent and Synergistic Combinatorial Efficacy of First-in-Class Small Molecule Imipridone ONC201 in Hematological Malignancies In Vitro and In Vivo through Apoptosis Via the... von Prabhu, Varun Vijay, Talekar, Mala Kiran, Lulla, Amriti R, Kline, C. Leah B, Zhou, Lanlan, Hall, Junior, Van den Heuvel, A. Pieter J, Dicker, David T, Grupp, Stephan A, Garnett, Mathew, McDermott, Ultan, Benes, Cyril H, Pu, Jeffrey J, Claxton, David F, Oster, Wolfgang, Allen, Joshua E., El-Deiry, Wafik S.

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Abstract 2497: ONC201 targets cancer stem cells in colorectal, prostate and glioblastoma multiforme tumors via modulation of stem cell-related gene expression von Prabhu, Varun Vijay, Allen, Joshua E., Zhao, Dan, Lulla, Amriti R., Kline, Christina Leah B., van den Heuvel, A. Pieter J., Lev, Avital, Batchelor, Tracy T., Dicker, David T., Chi, Andrew S., El-Deiry, Wafik S.

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Small molecule NSC59984 restores p53 pathway signaling and anti-tumor effects against colorectal cancer via p73 activation and degradation of mutant p53 von Zhang, Shengliang, Zhou, Lanlan, Hong, Bo, van den Heuvel, A. Pieter J., Prabhu, Varun V., Warfel, Noel A., Kline, Christina Leah B., Dicker, David T., Kopelovich, Levy, El-Deiry, Wafik S.

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Prodigiosin rescues deficient p53 signaling and anti-tumor effects via up-regulating p73 and disrupting its interaction with mutant p53 von Hong, Bo, Prabhu, Varun V., Zhang, Shengliang, van den Heuvel, A. Pieter J., Dicker, David T., Kopelovich, Levy, El-Deiry, Wafik S.

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Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors von Prabhu, Varun V, Lulla, Amriti R, Madhukar, Neel S, Ralff, Marie D, Zhao, Dan, Kline, Christina Leah B, Van den Heuvel, A. Pieter J, Lev, Avital, Garnett, Mathew J, McDermott, Ultan, Benes, Cyril H, Batchelor, Tracy T, Chi, Andrew S, Elemento, Olivier, Allen, Joshua E, El-Deiry, Wafik S

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Single agent and synergistic combinatorial efficacy of first-in-class small molecule imipridone ONC201 in hematological malignancies von Varun V. Prabhu, Talekar, Mala K., Amriti R. Lulla, C. Leah B. Kline, Lanlan Zhou, Junior Hall, A. Pieter J. Van Den Heuvel, Dicker, David T., Babar, Jawad, Grupp, Stephan A., Garnett, Mathew J., McDermott, Ultan, Benes, Cyril H., Pu, Jeffrey J., Claxton, David F., Khan, Nadia, Oster, Wolfgang, Allen, Joshua E., El-Deiry, Wafik S.

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Single agent and synergistic combinatorial efficacy of first-in-class small molecule imipridone ONC201 in hematological malignancies von Prabhu, Varun V., Talekar, Mala K., Lulla, Amriti R., Kline, C. Leah B., Zhou, Lanlan, Hall, Junior, Van den Heuvel, A. Pieter J., Dicker, David T., Babar, Jawad, Grupp, Stephan A., Garnett, Mathew J., McDermott, Ultan, Benes, Cyril H., Pu, Jeffrey J., Claxton, David F., Khan, Nadia, Oster, Wolfgang, Allen, Joshua E., El-Deiry, Wafik S.

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Thrombus Aspiration during Primary Percutaneous Coronary Intervention von Svilaas, Tone, Vlaar, Pieter J, van der Horst, Iwan C, Diercks, Gilles F.H, de Smet, Bart J.G.L, van den Heuvel, Ad F.M, Anthonio, Rutger L, Jessurun, Gillian A, Tan, Eng-Shiong, Suurmeijer, Albert J.H, Zijlstra, Felix

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Cardiac death and reinfarction after 1 year in the Thrombus Aspiration during Percutaneous coronary intervention in Acute myocardial infarction Study (TAPAS): a 1-year follow-up st... von Vlaar, Pieter J, MSc, Svilaas, Tone, MD, van der Horst, Iwan C, MD, Diercks, Gilles FH, MD, Fokkema, Marieke L, de Smet, Bart JGL, MD, van den Heuvel, Ad FM, MD, Anthonio, Rutger L, MD, Jessurun, Gillian A, MD, Tan, Eng-Shiong, MD, Suurmeijer, Albert JH, MD, Zijlstra, Felix, MD

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Reduced dopamine transporter binding predates impulse control disorders in Parkinson's disease von Vriend, Chris, Nordbeck, Anna H., Booij, Jan, van der Werf, Ysbrand D., Pattij, Tommy, Voorn, Pieter, Raijmakers, Pieter, Foncke, Elisabeth M.J., van de Giessen, Elsmarieke, Berendse, Henk W., van den Heuvel, Odile A.

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