Cytotoxic and Apoptotic Effects of C-Myc Inhibition by 10058-F4 on Acute Promyelocytic Leukemia Cells von M Sayyadi, A Safaroghli-Azar, D Bashash

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Anti-Cancer Effect of Aprepitant on Nb4 Leukemic Cells von E Razani, S Bayati, A Safaroghli Azar, D Bashash, AH Ghafari

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Apoptotic Effect of Phosphatidylinositol 3-Kinase Inhibition on Acute Lymphoblastic Leukemia Cells Using Buparlisib von MR Sadri, A Safaroghli Azar, AR Kazemi, M Hamidpour, M Allahbakhshian Frasani, D Bashash

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Apoptotic effect of Kyprolis on multiple myeloma KMM-1 cellsthrough p73-mediated induction of G1 cell cycle arrest von Kazemi A, Sadri M.R, Safaroghli-Azar A, Pourbagheri-Sigaroodi A, Allahbakhshian-Farsani M, Vazifeh Shiran N, Bashash D

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The PI3K/Akt signaling axis in Alzheimer’s disease: a valuable target to stimulate or suppress? von Razani, Elham, Pourbagheri-Sigaroodi, Atieh, Safaroghli-Azar, Ava, Zoghi, Anahita, Shanaki-Bavarsad, Mahsa, Bashash, Davood

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Suppression of c‐Myc using 10058‐F4 exerts caspase‐3‐dependent apoptosis and intensifies the antileukemic effect of vincristine in pre‐B acute lymphoblastic leukemia cells... von Sheikh‐Zeineddini, Negar, Bashash, Davood, Safaroghli‐Azar, Ava, Riyahi, Niknam, Shabestari, Rima Manafi, Janzamin, Ehsan, Safa, Majid

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The PI3K/Akt/mTORC signaling axis in head and neck squamous cell carcinoma: Possibilities for therapeutic interventions either as single agents or in combination with conventional... von Akbari Dilmaghani, Nader, Safaroghli‐Azar, Ava, Pourbagheri‐Sigaroodi, Atieh, Bashash, Davood

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Small molecule inhibitor of c-Myc 10058-F4 inhibits proliferation and induces apoptosis in acute leukemia cells, irrespective of PTEN status von Bashash, Davood, Sayyadi, Mohamad, Safaroghli-Azar, Ava, Sheikh-Zeineddini, Negar, Riyahi, Niknam, Momeny, Majid

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Pan-HDAC inhibitor panobinostat, as a single agent or in combination with PI3K inhibitor, induces apoptosis in APL cells: An emerging approach to overcome MSC-induced resistance von Mosleh, Mohammad, Safaroghli-Azar, Ava, Bashash, Davood

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Melatonin, an inhibitory agent in breast cancer von Nooshinfar, Elaheh, Safaroghli-Azar, Ava, Bashash, Davood, Akbari, Mohammad Esmaeil

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C-Myc inhibition sensitizes pre-B ALL cells to the anti-tumor effect of vincristine by altering apoptosis and autophagy: Proposing a probable mechanism of action for 10058-F4 von Sheikh‐Zeineddini, Negar, Safaroghli-azar, Ava, Salari, Sina, Bashash, Davood

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Anti‐leukemic effect of PI3K inhibition on chronic myeloid leukemia (CML) cells: shedding new light on the mitigating effect of c‐Myc and autophagy on BKM120 cytotoxicity von Shiri Heris, Reza, Safaroghli‐Azar, Ava, Yousefi, Amir‐Mohammad, Hamidpour, Mohsen, Bashash, Davood

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Phosphoinositide 3-kinase (PI3K) classes: From cell signaling to endocytic recycling and autophagy von Safaroghli-Azar, Ava, Sanaei, Mohammad-Javad, Pourbagheri-Sigaroodi, Atieh, Bashash, Davood

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Platelets in the perspective of COVID-19; pathophysiology of thrombocytopenia and its implication as prognostic and therapeutic opportunity von Delshad, Mahda, Safaroghli-Azar, Ava, Pourbagheri-Sigaroodi, Atieh, Poopak, Behzad, Shokouhi, Shervin, Bashash, Davood

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The contributory role of lymphocyte subsets, pathophysiology of lymphopenia and its implication as prognostic and therapeutic opportunity in COVID-19 von Delshad, Mahda, Tavakolinia, Naeimeh, Pourbagheri-Sigaroodi, Atieh, Safaroghli-Azar, Ava, Bagheri, Nader, Bashash, Davood

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Inhibitor of pan class-I PI3K induces differentially apoptotic pathways in acute leukemia cells: Shedding new light on NVP-BKM120 mechanism of action von Bashash, Davood, Safaroghli-Azar, Ava, Delshad, Mahda, Bayati, Samaneh, Nooshinfar, Elaheh, Ghaffari, Seyed H.

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The PI3K/Akt/mTOR signaling pathway in gastric cancer; from oncogenic variations to the possibilities for pharmacologic interventions von Baghery Saghchy Khorasani, Ayda, Pourbagheri-Sigaroodi, Atieh, Pirsalehi, Ali, Safaroghli-azar, Ava, Zali, Mohammad Reza, Bashash, Davood

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Kinase inhibitors: Opportunities for small molecule anticancer immunotherapies von Safaroghli-Azar, Ava, Emadi, Fatemeh, Lenjisa, Jimma, Mekonnen, Laychiluh, Wang, Shudong

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Inhibition of PI3K pathway using BKM120 intensified the chemo-sensitivity of breast cancer cells to arsenic trioxide (ATO) von Alipour, Faranak, Riyahi, Niknam, Safaroghli-Azar, Ava, Sari, Soyar, Zandi, Zahra, Bashash, Davood

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Anticancer effect of pan-PI3K inhibitor on multiple myeloma cells: Shedding new light on the mechanisms involved in BKM120 resistance von Safaroghli-Azar, Ava, Bashash, Davood, Kazemi, Alireza, Pourbagheri-Sigaroodi, Atieh, Momeny, Majid

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