直鎖状ポリユビキチン鎖生成酵素LUBACの阻害剤開発: 疾患治療からLUBACの新たな機能解明まで von 坂本, 裕樹, 岩井, 一宏, 長野, 哲雄

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新たな炎症応答シグナル系, 直鎖状ユビキチン鎖とその生成異常による疾患 von 岩井一宏

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Roles of linear ubiquitinylation, a crucial regulator of NF-κB and cell death, in the immune system von Sasaki, Katsuhiro, Iwai, Kazuhiro

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Diverse roles of the ubiquitin system in NF-κB activation von Iwai, Kazuhiro

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Oxygen modulates iron homeostasis by switching iron sensing of NCOA4 von Kuno, Sota, Iwai, Kazuhiro

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Iron‐induced NCOA4 condensation regulates ferritin fate and iron homeostasis von Kuno, Sota, Fujita, Hiroaki, Tanaka, Yu‐ki, Ogra, Yasumitsu, Iwai, Kazuhiro

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Index markers of chronic fatigue syndrome with dysfunction of TCA and urea cycles von Yamano, Emi, Sugimoto, Masahiro, Hirayama, Akiyoshi, Kume, Satoshi, Yamato, Masanori, Jin, Guanghua, Tajima, Seiki, Goda, Nobuhito, Iwai, Kazuhiro, Fukuda, Sanae, Yamaguti, Kouzi, Kuratsune, Hirohiko, Soga, Tomoyoshi, Watanabe, Yasuyoshi, Kataoka, Yosky

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Role of linear ubiquitination in inflammatory responses and tissue homeostasis von Sasaki, Katsuhiro, Iwai, Kazuhiro

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Linear ubiquitination‐induced necrotic tumor remodeling elicits immune evasion von Sasaki, Katsuhiro, Hayamizu, Yoshie, Murakami, Ryuji, Toi, Masakazu, Iwai, Kazuhiro

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PRDX6 augments selenium utilization to limit iron toxicity and ferroptosis von Fujita, Hiroaki, Tanaka, Yu-ki, Ogata, Seiryo, Suzuki, Noriyuki, Kuno, Sota, Barayeu, Uladzimir, Akaike, Takaaki, Ogra, Yasumitsu, Iwai, Kazuhiro

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Iron-Induced Dissociation of the Aft1p Transcriptional Regulator from Target Gene Promoters Is an Initial Event in Iron-Dependent Gene Suppression von Ueta, Ryo, Fujiwara, Naoko, Iwai, Kazuhiro, Yamaguchi-Iwai, Yuko

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Structural insight into the recognition of the linear ubiquitin assembly complex by Shigella E3 ligase IpaH1.4/2.5 von Hiragi, Keito, Nishide, Akira, Takagi, Kenji, Iwai, Kazuhiro, Kim, Minsoo, Mizushima, Tsunehiro

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Cooperative Domain Formation by Homologous Motifs in HOIL-1L and SHARPIN Plays A Crucial Role in LUBAC Stabilization von Fujita, Hiroaki, Tokunaga, Akira, Shimizu, Satoshi, Whiting, Amanda L., Aguilar-Alonso, Francisco, Takagi, Kenji, Walinda, Erik, Sasaki, Yoshiteru, Shimokawa, Taketo, Mizushima, Tsunehiro, Ohki, Izuru, Ariyoshi, Mariko, Tochio, Hidehito, Bernal, Federico, Shirakawa, Masahiro, Iwai, Kazuhiro

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Differential involvement of LUBAC‐mediated linear ubiquitination in intestinal epithelial cells and macrophages during intestinal inflammation von Sakamoto, Yusuke, Sasaki, Katsuhiro, Omatsu, Mayuki, Hamada, Kensuke, Nakanishi, Yuki, Itatani, Yoshiro, Kawada, Kenji, Obama, Kazutaka, Seno, Hiroshi, Iwai, Kazuhiro

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Modulation of autoimmune pathogenesis by T cell-triggered inflammatory cell death von Sasaki, Katsuhiro, Himeno, Ai, Nakagawa, Tomoko, Sasaki, Yoshiteru, Kiyonari, Hiroshi, Iwai, Kazuhiro

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A de novo dominant-negative variant is associated with OTULIN-related autoinflammatory syndrome von Takeda, Yukiko, Ueki, Masahiro, Matsuhiro, Junpei, Walinda, Erik, Tanaka, Takayuki, Yamada, Masafumi, Fujita, Hiroaki, Takezaki, Shunichiro, Kobayashi, Ichiro, Tamaki, Sakura, Nagata, Sanae, Miyake, Noriko, Matsumoto, Naomichi, Osawa, Mitsujiro, Yasumi, Takahiro, Heike, Toshio, Ohtake, Fumiaki, Saito, Megumu K, Toguchida, Junya, Takita, Junko, Ariga, Tadashi, Iwai, Kazuhiro

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ES2-1 鉄代謝研究の現況 von 岩井一宏

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HOIL-1L deficiency induces cell cycle alteration which causes immaturity of skeletal muscle and cardiomyocytes von Akagi, Kentaro, Baba, Shiro, Fujita, Hiroaki, Fuseya, Yasuhiro, Yoshinaga, Daisuke, Kubota, Hirohito, Kume, Eitaro, Fukumura, Fumiaki, Matsuda, Koichi, Tanaka, Takayuki, Hirata, Takuya, Saito, Megumu K., Iwai, Kazuhiro, Takita, Junko

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Synergistic involvement of the NZF domains of the LUBAC accessory subunits HOIL-1L and SHARPIN in the regulation of LUBAC function von Toda, Yusuke, Fujita, Hiroaki, Mino, Koshiki, Koyama, Takuto, Matsuoka, Seiji, Kaizuka, Toshie, Agawa, Mari, Matsumoto, Shigeyuki, Idei, Akiko, Nishikori, Momoko, Okuno, Yasushi, Osada, Hiroyuki, Yoshida, Minoru, Takaori-Kondo, Akifumi, Iwai, Kazuhiro

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鉄代謝研究の進歩と鉄不応性貧血・感染防御への関わり von 菱川, 恭子, 岩井, 一宏

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