Welcome statement—npj Microgravity von Nickerson, Cheryl A

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Challenges and Opportunities for Bioactive Compound and Antibiotic Discovery in Deep Space von Simpson, Anna C.

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Spaceflight associated neuro-ocular syndrome (SANS) and the neuro-ophthalmologic effects of microgravity: a review and an update von Lee, Andrew G., Mader, Thomas H., Gibson, C. Robert, Tarver, William, Rabiei, Pejman, Riascos, Roy F., Galdamez, Laura A., Brunstetter, Tyson

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A systematic review and meta-analysis of bone loss in space travelers von Stavnichuk, Mariya, Mikolajewicz, Nicholas, Corlett, Tatsuya, Morris, Martin, Komarova, Svetlana V.

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A review of alterations to the brain during spaceflight and the potential relevance to crew in long-duration space exploration von Roy-O’Reilly, Meaghan, Mulavara, Ajitkumar, Williams, Thomas

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Update on the effects of microgravity on the musculoskeletal system von Juhl, Otto J., Buettmann, Evan G., Friedman, Michael A., DeNapoli, Rachel C., Hoppock, Gabriel A., Donahue, Henry J.

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How does spaceflight affect the acquired immune system? von Akiyama, Taishin, Horie, Kenta, Hinoi, Eiichi, Hiraiwa, Manami, Kato, Akihisa, Maekawa, Yoichi, Takahashi, Akihisa, Furukawa, Satoshi

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Neil Armstrong’s digital twin: An integrative approach for movement analysis in simulated space missions von Reimeir, Benjamin, Wargel, Anna, Riedl, Franziska, Maach, Sara, Weidner, Robert, Grömer, Gernot, Federolf, Peter

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Key points for the development of antioxidant cocktails to prevent cellular stress and damage caused by reactive oxygen species (ROS) during manned space missions von Gómez, Xavier, Sanon, Serena, Zambrano, Kevin, Asquel, Samira, Bassantes, Mariuxi, Morales, Julián E., Otáñez, Gabriela, Pomaquero, Core, Villarroel, Sarah, Zurita, Alejandro, Calvache, Carlos, Celi, Kathlyn, Contreras, Terry, Corrales, Dylan, Naciph, María Belén, Peña, José, Caicedo, Andrés

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Latent virus reactivation in astronauts on the international space station von Mehta, Satish K., Laudenslager, Mark L., Stowe, Raymond P., Crucian, Brian E., Feiveson, Alan H., Sams, Clarence F., Pierson, Duane L.

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Alterations in adaptive immunity persist during long-duration spaceflight von Crucian, Brian, Stowe, Raymond P, Mehta, Satish, Quiriarte, Heather, Pierson, Duane, Sams, Clarence

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The effects of real and simulated microgravity on cellular mitochondrial function von Nguyen, Hong Phuong, Tran, Phuong Hoa, Kim, Kyu-Sung, Yang, Su-Geun

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Red risks for a journey to the red planet: The highest priority human health risks for a mission to Mars von Patel, Zarana S., Brunstetter, Tyson J., Tarver, William J., Whitmire, Alexandra M., Zwart, Sara R., Smith, Scott M., Huff, Janice L.

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Macrophages in microgravity: the impact of space on immune cells von Ludtka, Christopher, Silberman, Justin, Moore, Erika, Allen, Josephine B.

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Trabecular bone organoids: a micron-scale ‘humanised’ prototype designed to study the effects of microgravity and degeneration von Iordachescu, Alexandra, Hughes, Erik A. B., Joseph, Stephan, Hill, Eric J., Grover, Liam M., Metcalfe, Anthony D.

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Interplay of space radiation and microgravity in DNA damage and DNA damage response von Moreno-Villanueva, María, Wong, Michael, Lu, Tao, Zhang, Ye, Wu, Honglu

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Effects of exercise countermeasures on multisystem function in long duration spaceflight astronauts von Scott, Jessica M., Feiveson, Alan H., English, Kirk L., Spector, Elisabeth R., Sibonga, Jean D., Dillon, E. Lichar, Ploutz-Snyder, Lori, Everett, Meghan E.

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Towards sustainable human space exploration—priorities for radiation research to quantify and mitigate radiation risks von Fogtman, Anna, Baatout, Sarah, Baselet, Bjorn, Berger, Thomas, Hellweg, Christine E., Jiggens, Piers, La Tessa, Chiara, Narici, Livio, Nieminen, Petteri, Sabatier, Laure, Santin, Giovanni, Schneider, Uwe, Straube, Ulrich, Tabury, Kevin, Tinganelli, Walter, Walsh, Linda, Durante, Marco

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Brain structural plasticity with spaceflight von Koppelmans, Vincent, Bloomberg, Jacob J, Mulavara, Ajitkumar P, Seidler, Rachael D

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High intensity training during spaceflight: results from the NASA Sprint Study von English, Kirk L., Downs, Meghan, Goetchius, Elizabeth, Buxton, Roxanne, Ryder, Jeffrey W., Ploutz-Snyder, Robert, Guilliams, Mark, Scott, Jessica M., Ploutz-Snyder, Lori L.

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