Dose optimization of β-lactam antibiotics in children: from population pharmacokinetics to individualized therapy von Ngougni Pokem, Perrin, Vanneste, Dorian, Schouwenburg, Stef, Abdulla, Alan, Gijsen, Matthias, Dhont, Evelyn, van der Linden, Dimitri, Spriet, Isabel, De Cock, Pieter, Koch, Birgit, Van Bambeke, Francoise, Wijnant, Gert-Jan

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Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily von Marchitti, Satori A, Brocker, Chad, Stagos, Dimitrios, Vasiliou, Vasilis

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The Simcyp® Population-based ADME Simulator von Jamei, Masoud, Marciniak, Steve, Feng, Kairui, Barnett, Adrian, Tucker, Geoffrey, Rostami-Hodjegan, Amin

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Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and induction von Martignoni, Marcella, Groothuis, Geny MM, de Kanter, Ruben

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Pharmacokinetics during therapeutic hypothermia in neonates: from pathophysiology to translational knowledge and physiologically-based pharmacokinetic (PBPK) modeling von Leys, Karen, Stroe, Marina-Stefania, Annaert, Pieter, Van Cruchten, Steven, Carpentier, Sebastien, Allegaert, Karel, Smits, Anne

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Current and future physiologically based pharmacokinetic (PBPK) modeling approaches to optimize pharmacotherapy in preterm neonates von Allegaert, Karel, Abbasi, Mohammad Yaseen, Annaert, Pieter, Olafuyi, Olusola

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Pharmacokinetic modelling and Bayesian estimation-assisted decision tools to optimize vancomycin dosage in neonates: only one piece of the puzzle von Allegaert, Karel, Flint, Robert, Smits, Anne

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Antisense oligonucleotide pharmacokinetics and metabolism von Geary, Richard S

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Safety of medicines during breastfeeding - from case report to modeling: a contribution from the ConcePTION project von Cardoso, Evelina, Guidi, Monia, Nauwelaerts, Nina, Nordeng, Hedvig, Teil, Marie, Allegaert, Karel, Smits, Anne, Gandia, Peggy, Edginton, Andrea, Ito, Shinya, Annaert, Pieter, Panchaud, Alice

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The Caco-2 cell monolayer: usefulness and limitations von Sun, Huadong, Chow, Edwin CY, Liu, Shanjun, Du, Yimin, Pang, K Sandy

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An update on pharmacogenetic factors influencing the metabolism and toxicity of artemisinin-based combination therapy in the treatment of malaria von Pernaute-Lau, L, Camara, M, De Sousa, TN, Morris, U, Ferreira, MU, Gil, JP

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Pharmacokinetic drug evaluation of letermovir prophylaxis for cytomegalovirus in hematopoietic stem cell transplantation von Deleenheer, Barbara, Spriet, Isabel, Maertens, Johan

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Genetic polymorphisms of uptake (OATP1B1, 1B3) and efflux (MRP2, BCRP) transporters: implications for inter-individual differences in the pharmacokinetics and pharmacodynamics of s... von Ieiri, Ichiro, Higuchi, Shun, Sugiyama, Yuichi

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Toxicity of MRI and CT contrast agents von Hasebroock, Kendra M, Serkova, Natalie J

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Pharmacokinetic considerations for pediatric patients receiving analgesia in the intensive care unit; targeting postoperative, ECMO and hypothermia patients von Zeilmaker, Gerdien A, Pokorna, Paula, Mian, Paola, Wildschut, Enno D, Knibbe, Catherijne A.J, Krekels, Elke H.J, Allegaert, Karel, Tibboel, Dick

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Neuroinflammation and microglia: considerations and approaches for neurotoxicity assessment von Harry, Gaylia Jean, Kraft, Andrew D

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The role of CYP26 enzymes in retinoic acid clearance von Thatcher, Jayne E, Isoherranen, Nina

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Development of inhibitors of ATP-binding cassette drug transporters - present status and challenges von Shukla, Suneet, Wu, Chung-Pu, Ambudkar, Suresh V

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The effect of chronic renal failure on drug metabolism and transport von Dreisbach, Albert W, Lertora, Juan JL

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Physicochemical drug properties associated with in vivo toxicological outcomes: a review von Price, David A, Blagg, Julian, Jones, Lyn, Greene, Nigel, Wager, Travis

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